Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anaísa V. Ferreira"'
Autor:
Anaísa V. Ferreira, Juan Carlos Alarcon-Barrera, Jorge Domínguez-Andrés, Özlem Bulut, Gizem Kilic, Priya A. Debisarun, Rutger J. Röring, Hatice N. Özhan, Eva Terschlüsen, Athanasios Ziogas, Sarantos Kostidis, Yassene Mohammed, Vasiliki Matzaraki, George Renieris, Evangelos J. Giamarellos-Bourboulis, Mihai G. Netea, Martin Giera
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Infections and vaccines can induce enhanced long-term responses in innate immune cells, establishing an innate immunological memory termed trained immunity. Here, we show that monocytes with a trained immunity phenotype, due to exposure to t
Externí odkaz:
https://doaj.org/article/8d55ada0d53e44d18afec045e805fbf3
Autor:
Anaísa V. Ferreira, Sarantos Kostidis, Laszlo A. Groh, Valerie A.C.M. Koeken, Mariolina Bruno, Ilayda Baydemir, Gizem Kilic, Özlem Bulut, Theano Andriopoulou, Victoria Spanou, Kalliopi D. Synodinou, Theologia Gkavogianni, Simone J.C.F.M. Moorlag, L. Charlotte de Bree, Vera P. Mourits, Vasiliki Matzaraki, Werner J.H. Koopman, Frank L. van de Veerdonk, Georgios Renieris, Martin Giera, Evangelos J. Giamarellos-Bourboulis, Boris Novakovic, Jorge Domínguez-Andrés
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112658- (2023)
Summary: Itaconate is an immunomodulatory metabolite produced by immune cells under microbial stimulation and certain pro-inflammatory conditions and triggers antioxidant and anti-inflammatory responses. We show that dimethyl itaconate, a derivative
Externí odkaz:
https://doaj.org/article/6e7649ccdf4846afb0796f373689a5d6
Autor:
Jorge Domínguez-Andrés, Rob J.W. Arts, Siroon Bekkering, Harsh Bahrar, Bastiaan A. Blok, L. Charlotte J. de Bree, Mariolina Bruno, Özlem Bulut, Priya A. Debisarun, Helga Dijkstra, Jéssica Cristina dos Santos, Anaísa V. Ferreira, Daniela Flores-Gomez, Laszlo A. Groh, Inge Grondman, Leonie Helder, Cor Jacobs, Liesbeth Jacobs, Trees Jansen, Gizem Kilic, Viola Klück, Valerie A.C.M. Koeken, Heidi Lemmers, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jelmer H. van Puffelen, Katrin Rabold, Rutger J. Röring, Diletta Rosati, Helin Tercan, Julia van Tuijl, Jessica Quintin, Reinout van Crevel, Niels P. Riksen, Leo A.B. Joosten, Mihai G. Netea
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100365- (2021)
Summary: A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed “trained immunity.” We outline he
Externí odkaz:
https://doaj.org/article/e0ee4ea53a9e4be785098507068f1cd9
Autor:
Mihai G. Netea, Jorge Domínguez-Andrés, Rienke F Uijen, Anaísa V Ferreira, Marien I. de Jonge, Ozlem Bulut
Publikováno v:
Journal of Leukocyte Biology, 111, 1, pp. 9-17
Journal of Leukocyte Biology, 111, 9-17
Journal of Leukocyte Biology, 111, 9-17
Contains fulltext : 248219.pdf (Publisher’s version ) (Open Access) Trained immunity is a de facto memory of innate immune cells, resulting in a long-term increase in innate host defense mechanisms after infection. The long-term heterologous protec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f09b04b45d4446d0b687d75a088a508c
Autor:
Trees Jansen, Rab K. Prinjha, Anaísa V Ferreira, Rebecca C. Furze, Nicholas Smithers, Mihai G. Netea, Jorge Domínguez-Andrés
Publikováno v:
European Journal of Immunology, 49, 2044-2050
European Journal of Immunology, 49, 11, pp. 2044-2050
European Journal of Immunology
European Journal of Immunology, 49, 11, pp. 2044-2050
European Journal of Immunology
Changes in the epigenetic landscape of immune cells are a crucial component of gene activation during the induction of inflammatory responses, therefore it has been hypothesized that epigenetic modulation could be employed to restore homeostasis in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4375b4e76740131d3d10ff08c1165f10
https://doi.org/10.1002/eji.201848081
https://doi.org/10.1002/eji.201848081
Autor:
Anaísa V Ferreira, William Jones-Warner, Mariska Kerstholt, Leo A. B. Joosten, Shafaque Rahman, Michelle A. E. Brouwer, Marije Oosting, Guido J. E. J. Hooiveld, Mihai G. Netea
Publikováno v:
Ticks and Tick-borne Diseases, 12, 2
Ticks and Tick-borne Diseases, 12
Ticks and Tick-borne Diseases 12 (2021) 2
Ticks and Tick-borne Diseases, 12(2)
Ticks and Tick-borne Diseases, 12
Ticks and Tick-borne Diseases 12 (2021) 2
Ticks and Tick-borne Diseases, 12(2)
Antigen presentation is a crucial innate immune cell function that instructs adaptive immune cells. Loss of this pathway severely impairs the development of adaptive immune responses. To investigate whether B. burgdorferi sensu lato. spirochetes modu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272145e55de29bc3d9e335003aebdf1b
https://hdl.handle.net/2066/231361
https://hdl.handle.net/2066/231361
Autor:
Anaísa V Ferreira, Trees Jansen, Nicholas Smithers, Jorge Domínguez-Andrés, Rab K. Prinjha, Rebecca C. Furze, Mihai G. Netea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9332fc7fdf0453d173b14ba0ff032f41
https://doi.org/10.1002/eji.201848081/v2/response1
https://doi.org/10.1002/eji.201848081/v2/response1
Publikováno v:
Aging (Albany, N.Y.), 11, 3898-3899
Aging (Albany, N.Y.), 11, 12, pp. 3898-3899
Aging (Albany NY)
Aging (Albany, N.Y.), 11, 12, pp. 3898-3899
Aging (Albany NY)
Contains fulltext : 206784.pdf (Publisher’s version ) (Open Access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da10a8d9680538db74d5c0da865a664b
http://hdl.handle.net/2066/206784
http://hdl.handle.net/2066/206784
Autor:
Anaisa V. Ferreira, Valerie A. C. M. Koeken, Vasiliki Matzaraki, Sarantos Kostidis, Juan Carlos Alarcon-Barrera, L. Charlotte J. de Bree, Simone J. C. F. M. Moorlag, Vera P. Mourits, Boris Novakovic, Martin A. Giera, Mihai G. Netea, Jorge Domínguez-Andrés
Publikováno v:
Cells, Vol 10, Iss 5, p 971 (2021)
The innate immune system displays heterologous memory characteristics, which are characterized by stronger responses to a secondary challenge. This phenomenon termed trained immunity relies on epigenetic and metabolic rewiring of innate immune cells.
Externí odkaz:
https://doaj.org/article/d36d52f9a9ed45fbbd5ac61494727205
Autor:
Vera P Mourits, Jelmer H vanPuffelen, Boris Novakovic, Mariolina Bruno, Anaísa V Ferreira, Rob JW Arts, Laszlo Groh, Tania O Crișan, Jelle Zwaag, Elisa Jentho, Matthijs Kox, Peter Pickkers, Frank L van deVeerdonk, Sebastian Weis, Egbert Oosterwijk, Sita H Vermeulen, Mihai G Netea, Leo AB Joosten
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Abstract Objectives Histone methyltransferase G9a, also known as Euchromatic Histone Lysine Methyltransferase 2 (EHMT2), mediates H3K9 methylation which is associated with transcriptional repression. It possesses immunomodulatory effects and is overe
Externí odkaz:
https://doaj.org/article/6241b566bf084db2b5a557cb91065978