Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ana, Velic"'
Autor:
Priscila Pereira Sena, Jonasz Jeremiasz Weber, Sercan Bayezit, Rafael Saup, Rana Dilara Incebacak Eltemur, Xiaoling Li, Ana Velic, Jaqueline Jung, Boris Macek, Huu Phuc Nguyen, Olaf Riess, Thorsten Schmidt
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Lysine residues are one of the main sites for posttranslational modifications of proteins, and lysine ubiquitination of the Machado-Joseph disease protein ataxin-3 is implicated in its cellular function and polyglutamine expansion-dependent toxicity.
Externí odkaz:
https://doaj.org/article/ab398446675b41ffa6299a6e3522a89b
Autor:
Katharina Thomas, Lisa Zondler, Nadine Ludwig, Marina Kardell, Corinna Lüneburg, Katharina Henke, Sina Mersmann, Andreas Margraf, Tilmann Spieker, Tobias Tekath, Ana Velic, Richard Holtmeier, Juliane Hermann, Vera Jankowski, Melanie Meersch, Dietmar Vestweber, Martin Westphal, Johannes Roth, Michael A. Schäfers, John A. Kellum, Clifford A. Lowell, Jan Rossaint, Alexander Zarbock
Publikováno v:
JCI Insight, Vol 7, Iss 21 (2022)
Acute kidney injury (AKI) represents a common complication in critically ill patients that is associated with increased morbidity and mortality. In a murine AKI model induced by ischemia/reperfusion injury (IRI), we show that glutamine significantly
Externí odkaz:
https://doaj.org/article/30ea337b9c5d4c7ea8eab77560c841db
Autor:
Stefanie Dietz, Julian Schwarz, Ana Velic, Irene González-Menéndez, Leticia Quintanilla-Martinez, Nicolas Casadei, Alexander Marmé, Christian F. Poets, Christian Gille, Natascha Köstlin-Gille
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
During pregnancy, maternal immune system has to balance tightly between protection against pathogens and tolerance towards a semi-allogeneic organism. Dysfunction of this immune adaptation can lead to severe complications such as pregnancy loss, pree
Externí odkaz:
https://doaj.org/article/8cfd1af81a2d4baaa9ee618e44cfae93
Autor:
Tatjana Michel, Sonia Golombek, Heidrun Steinle, Ludmilla Hann, Ana Velic, Boris Macek, Stefanie Krajewski, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-11 (2019)
Abstract The application of synthetic modified messenger RNA (mRNA) is a promising approach for the treatment of a variety of diseases and vaccination. In the past few years, different modifications of synthetic mRNA were applied to render the mRNA m
Externí odkaz:
https://doaj.org/article/f2ac91389bdb445bbf44ad8f54392b17
Autor:
Markus W. Löffler, Christopher Mohr, Leon Bichmann, Lena Katharina Freudenmann, Mathias Walzer, Christopher M. Schroeder, Nico Trautwein, Franz J. Hilke, Raphael S. Zinser, Lena Mühlenbruch, Daniel J. Kowalewski, Heiko Schuster, Marc Sturm, Jakob Matthes, Olaf Riess, Stefan Czemmel, Sven Nahnsen, Ingmar Königsrainer, Karolin Thiel, Silvio Nadalin, Stefan Beckert, Hans Bösmüller, Falko Fend, Ana Velic, Boris Maček, Sebastian P. Haen, Luigi Buonaguro, Oliver Kohlbacher, Stefan Stevanović, Alfred Königsrainer, HEPAVAC Consortium, Hans-Georg Rammensee
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-16 (2019)
Abstract Background Although mutated HLA ligands are considered ideal cancer-specific immunotherapy targets, evidence for their presentation is lacking in hepatocellular carcinomas (HCCs). Employing a unique multi-omics approach comprising a neoepito
Externí odkaz:
https://doaj.org/article/09823055f7a9475c93077f42081ab4b7
Autor:
Stefan Hauser, Stefanie Schuster, Elena Heuten, Philip Höflinger, Jakob Admard, Yvonne Schelling, Ana Velic, Boris Macek, Stephan Ossowski, Ludger Schöls
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Disease modeling requires appropriate cellular models that best mimic the underlying pathophysiology. Human origin and an adequate expression of the disease protein are pre-requisites that support information from a model to be meaningful. In this st
Externí odkaz:
https://doaj.org/article/011df73636fb446083c5cb75672489e2
Autor:
Tobias Sinnberg, Elena Makino, Marcel A. Krueger, Ana Velic, Boris Macek, Ulrich Rothbauer, Nicola Groll, Oliver Pötz, Stefan Czemmel, Heike Niessner, Friedegund Meier, Kristian Ikenberg, Claus Garbe, Birgit Schittek
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 132-149 (2016)
Acquired resistance to second generation BRAF inhibitors (BRAFis), like vemurafenib is limiting the benefits of long term targeted therapy for patients with malignant melanomas that harbor BRAF V600 mutations. Since many resistance mechanisms have be
Externí odkaz:
https://doaj.org/article/2e1b05dd00f64c71ac1a7708866ee974
Autor:
Hartmut Stoll, Michael Ost, Anurag Singh, Roman Mehling, Davide Neri, Iris Schäfer, Ana Velic, Boris Macek, Dorothee Kretschmer, Christopher Weidenmaier, Andreas Hector, Rupert Handgretinger, Friedrich Götz, Andreas Peschel, Dominik Hartl, Nikolaus Rieber
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Staphylococcus aureus is one of the major human bacterial pathogens causing a broad spectrum of serious infections. Myeloid-derived suppressor cells (MDSC) represent an innate immune cell subset capable of regulating host-pathogen interactions, yet t
Externí odkaz:
https://doaj.org/article/2463ab7f472b421ca7d69dfa8c87d48a
Autor:
Fabio Lino Gratani, Petra Horvatek, Tobias Geiger, Marina Borisova, Christoph Mayer, Iwan Grin, Samuel Wagner, Wieland Steinchen, Gert Bange, Ana Velic, Boris Maček, Christiane Wolz
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007514 (2018)
The stringent response is characterized by (p)ppGpp synthesis resulting in repression of translation and reprogramming of the transcriptome. In Staphylococcus aureus, (p)ppGpp is synthesized by the long RSH (RelA/SpoT homolog) enzyme, RelSau or by on
Externí odkaz:
https://doaj.org/article/ae16293203d94614b64136f0d696a328
Autor:
Tobias Sinnberg, Christa Lichtensteiger, Omar Hasan Ali, Oltin T. Pop, Ann-Kristin Jochum, Lorenz Risch, Silvio D. Brugger, Ana Velic, David Bomze, Philipp Kohler, Pietro Vernazza, Werner C. Albrich, Christian R. Kahlert, Marie-Therese Abdou, Nina Wyss, Kathrin Hofmeister, Heike Niessner, Carl Zinner, Mara Gilardi, Alexandar Tzankov, Martin Röcken, Alex Dulovic, Srikanth Mairpady Shambat, Natalia Ruetalo, Philipp K. Buehler, Thomas C. Scheier, Wolfram Jochum, Lukas Kern, Samuel Henz, Tino Schneider, Gabriela M. Kuster, Maurin Lampart, Martin Siegemund, Roland Bingisser, Michael Schindler, Nicole Schneiderhan-Marra, Hubert Kalbacher, Kathy D. McCoy, Werner Spengler, Martin H. Brutsche, Boris Maček, Raphael Twerenbold, Josef M. Penninger, Matthias S. Matter, Lukas Flatz
Publikováno v:
American journal of respiratory and critical care medicine. 207(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2b8063a8544fa992994cd04fbfe676
https://pubmed.ncbi.nlm.nih.gov/35976979
https://pubmed.ncbi.nlm.nih.gov/35976979