Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ana, Sampedro"'
Autor:
Pablo Hervella, Maria Luz Alonso-Alonso, Ana Sampedro-Viana, Manuel Rodríguez-Yáñez, Iria López-Dequidt, José M. Pumar, Alberto Ouro, Daniel Romaus-Sanjurjo, Francisco Campos, Tomás Sobrino, José Castillo, Yago Leira, Ramón Iglesias-Rey
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Cerebral small vessel disease is the most common cause of lacunar strokes (LS). Understanding LS pathogenesis is vital for predicting disease severity, prognosis, and developing therapies. Objectives: To research molecular profiles that d
Externí odkaz:
https://doaj.org/article/0cf9474c500747d7b5e39283f032998b
Autor:
Ana Sampedro-Viana, Sabela Fernández-Rodicio, José Castillo, Pablo Hervella, María Luz Alonso-Alonso, Ramón Iglesias-Rey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9792 (2024)
The blood–brain barrier (BBB) is essential for protection and plays a crucial role in chronic neurological disorders like small-vessel disease and Alzheimer’s disease. Its complexity poses significant challenges for effective diagnostics and trea
Externí odkaz:
https://doaj.org/article/cdff4bbacb934e9a9c4ad053d4a9fbbf
Autor:
Pablo Hervella, Ana Sampedro-Viana, Sabela Fernández-Rodicio, Manuel Rodríguez-Yáñez, Iria López-Dequidt, José M. Pumar, Antonio J. Mosqueira, Marcos Bazarra-Barreiros, María Teresa Abengoza-Bello, Sara Ortega-Espina, Alberto Ouro, María Pérez-Mato, Francisco Campos, Tomás Sobrino, José Castillo, Maria Luz Alonso-Alonso, Ramón Iglesias-Rey
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6554 (2024)
Glutamate grabbers, such as glutamate oxaloacetate transaminase (GOT), have been proposed to prevent excitotoxicity secondary to high glutamate levels in stroke patients. However, the efficacy of blood glutamate grabbing by GOT could be dependent on
Externí odkaz:
https://doaj.org/article/2edfd97f31e44cc4a2a4245a735c3156
Autor:
Sabela Fernández-Rodicio, Gonzalo Ferro-Costas, Ana Sampedro-Viana, Marcos Bazarra-Barreiros, Alba Ferreirós, Esteban López-Arias, María Pérez-Mato, Alberto Ouro, José M. Pumar, Antonio J. Mosqueira, María Luz Alonso-Alonso, José Castillo, Pablo Hervella, Ramón Iglesias-Rey
Publikováno v:
Frontiers in Neuroinformatics, Vol 17 (2023)
IntroductionDynamic susceptibility-weighted contrast-enhanced (DSC) perfusion studies in magnetic resonance imaging (MRI) provide valuable data for studying vascular cerebral pathophysiology in different rodent models of brain diseases (stroke, tumor
Externí odkaz:
https://doaj.org/article/97f387ceeee746d79e2bd16d04625f0f
Autor:
Daniel Jericó, Karol M. Córdoba, Lei Jiang, Caroline Schmitt, María Morán, Ana Sampedro, Manuel Alegre, María Collantes, Eva Santamaría, Estíbaliz Alegre, Corinne Culerier, Ander Estella-Hermoso de Mendoza, Julen Oyarzabal, Miguel A. Martín, Iván Peñuelas, Matías A. Ávila, Laurent Gouya, Paolo G.V. Martini, Antonio Fontanellas
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 207-219 (2021)
Variegate porphyria (VP) results from haploinsufficiency of protoporphyrinogen oxidase (PPOX), the seventh enzyme in the heme synthesis pathway. There is no VP model that recapitulates the clinical manifestations of acute attacks. Combined administra
Externí odkaz:
https://doaj.org/article/f0e88f862dcd434c9fb48ea42beb448a
Autor:
Miriam Longo, Daniel Jericó, Karol M. Córdoba, José Ignacio Riezu-Boj, Raquel Urtasun, Isabel Solares, Ana Sampedro, María Collantes, Ivan Peñuelas, María Jesús Moreno-Aliaga, Matías A. Ávila, Elena Di Pierro, Miguel Barajas, Fermín I. Milagro, Paola Dongiovanni, Antonio Fontanellas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11938 (2023)
Acute intermittent porphyria (AIP) is a metabolic disorder caused by mutations in the porphobilinogen deaminase (PBGD) gene, encoding the third enzyme of the heme synthesis pathway. Although AIP is characterized by low clinical penetrance (~1% of PBG
Externí odkaz:
https://doaj.org/article/4f05cfbbec6f45b288b2bf102e5b5aba
Autor:
Antón Costa Rico, Ana Sampedro Garrido
Publikováno v:
Cabás, Iss 27 (2022)
El Movimiento Cooperativo de Escuela Popular (MCEP), uno de los movimientos de renovación pedagógica existentes en España, nacido en los momentos finales del franquismo, acumula una intensa historia desde su inspiración en la Pedagogía Freinet.
Externí odkaz:
https://doaj.org/article/ab74110470354bee86d96c9db28b6e9e
Autor:
Maria Luz Alonso-Alonso, Ana Sampedro-Viana, Manuel Rodríguez-Yáñez, Iria López-Dequidt, José M. Pumar, Antonio J. Mosqueira, Sabela Fernández-Rodicio, Marcos Bazarra-Barreiros, Tomás Sobrino, Francisco Campos, José Castillo, Pablo Hervella, Ramón Iglesias-Rey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3746 (2023)
The circadian system regulates numerous physiological variables, including body temperature. Additionally, a circadian patter has been described in stroke onset. Considering this, we hypothesised that the chronobiology of temperature may have an impa
Externí odkaz:
https://doaj.org/article/8efbcbc2b9ba406d820242c5e9cf7d61
Autor:
Daniel Jericó, Karol M. Córdoba, Ana Sampedro, Lei Jiang, Gilles Joucla, Charlotte Cabanne, José Luis Lanciego, Paolo G. V. Martini, Pedro Berraondo, Matías A. Ávila, Antonio Fontanellas
Publikováno v:
Life, Vol 12, Iss 11, p 1858 (2022)
Rare diseases, especially monogenic diseases, which usually affect a single target protein, have attracted growing interest in drug research by encouraging pharmaceutical companies to design and develop therapeutic products to be tested in the clinic
Externí odkaz:
https://doaj.org/article/e85dc083829242d0a9443dcdb8a9237a
Autor:
María Luz Alonso-Alonso, María Pérez-Mato, Ana Sampedro-Viana, Clara Correa-Paz, Paulo Ávila-Gómez, Tomás Sobrino, Francisco Campos, José Castillo, Ramón Iglesias-Rey, Pablo Hervella
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2156 (2022)
Recanalization of the occluded artery is the gold standard treatment for acute ischemic stroke, which includes enzymatic fibrinolytic treatment with the use of recombinant tissue plasminogen activators (rtPAs) to disrupt the occluding clot, the use o
Externí odkaz:
https://doaj.org/article/4f2f88bcae7047019a6b33cea92bd12a