Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ana, Graf"'
Autor:
Ronald C. Petersen, Ana Graf, Chris Brady, Susan De Santi, Hana Florian, Jaren Landen, Mike Pontecorvo, Christopher Randolph, Kaycee M. Sink, Maria C. Carrillo, Christopher J. Weber
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract Alzheimer's disease (AD) staging criteria lack standardized, empirical description. Well‐defined AD staging criteria are an important consideration in protocol design, influencing a more standardized inclusion/exclusion criteria and defini
Externí odkaz:
https://doaj.org/article/3165a19f6e46401bb79c035cd29ef3bd
Autor:
Angelika Caputo, Amy Racine, Ines Paule, Pierre N. Tariot, Jessica B. Langbaum, Neva Coello, Marie-Emmanuelle Riviere, J. Michael Ryan, Cristina Lopez Lopez, Ana Graf, for the National Alzheimer’s Coordinating Center, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background There is a critical need for novel primary endpoints designed to detect early and subtle changes in cognition in clinical trials targeting the asymptomatic (preclinical) phase of Alzheimer’s disease (AD). The Alzheimer’s Preve
Externí odkaz:
https://doaj.org/article/b6f0a45931354595ad372db4809d8620
Autor:
Jessica B. Langbaum, Noel N. Ellison, Angelika Caputo, Ronald G. Thomas, Carolyn Langlois, Marie-Emmanuelle Riviere, Ana Graf, Cristina Lopez Lopez, Eric M. Reiman, Pierre N. Tariot, Suzanne B. Hendrix
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background There is growing interest in identifying sensitive composite cognitive tests to serve as primary endpoints in preclinical Alzheimer’s disease (AD) treatment trials. We reported previously a composite cognitive test score sensiti
Externí odkaz:
https://doaj.org/article/e7c88447f10341739672d2101169bc6e
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/9c8a02b31379448c85dc22ad3109b93e
Autor:
Ulf Neumann, Mike Ufer, Laura H Jacobson, Marie‐Laure Rouzade‐Dominguez, Gunilla Huledal, Carine Kolly, Rainer M Lüönd, Rainer Machauer, Siem J Veenstra, Konstanze Hurth, Heinrich Rueeger, Marina Tintelnot‐Blomley, Matthias Staufenbiel, Derya R Shimshek, Ludovic Perrot, Wilfried Frieauff, Valerie Dubost, Hilmar Schiller, Barbara Vogg, Karen Beltz, Alexandre Avrameas, Sandrine Kretz, Nicole Pezous, Jean‐Michel Rondeau, Nicolau Beckmann, Andreas Hartmann, Stefan Vormfelde, Olivier J David, Bruno Galli, Rita Ramos, Ana Graf, Cristina Lopez Lopez
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 11, Pp 1-18 (2018)
Abstract The beta‐site amyloid precursor protein cleaving enzyme‐1 (BACE‐1) initiates the generation of amyloid‐β (Aβ), and the amyloid cascade leading to amyloid plaque deposition, neurodegeneration, and dementia in Alzheimer's disease (AD
Externí odkaz:
https://doaj.org/article/48fbf5e81f1a4f18ae40665093c63175
Autor:
Angelika Caputo, Amy Racine, Ines Paule, Pierre N. Tariot, Jessica B. Langbaum, Neva Coello, Marie-Emmanuelle Riviere, J. Michael Ryan, Cristina Lopez Lopez, Ana Graf
Background: There is a critical need for novel primary endpoints designed to detect early and subtle changes in cognition in clinical trials targeting the asymptomatic (preclinical) phase of Alzheimer’s disease (AD). The Alzheimer’s Prevention In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a9b9d0026190972bee5101a1849806
https://doi.org/10.21203/rs.3.rs-2226991/v1
https://doi.org/10.21203/rs.3.rs-2226991/v1
Autor:
Marie-Emmanuelle Riviere, Carolyn Langlois, Ana Graf, Cristina Lopez Lopez, Eric M. Reiman, Suzanne Hendrix, Pierre N. Tariot, Ronald G. Thomas, Angelika Caputo, Noel Ellison, Jessica B. Langbaum
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Alzheimer's Research & Therapy
Alzheimer's Research & Therapy
Background There is growing interest in identifying sensitive composite cognitive tests to serve as primary endpoints in preclinical Alzheimer’s disease (AD) treatment trials. We reported previously a composite cognitive test score sensitive to tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddea34f5ad6f75e4038e7c53ff56d563
http://link.springer.com/article/10.1186/s13195-020-00633-2
http://link.springer.com/article/10.1186/s13195-020-00633-2
Autor:
Yu Nakamura, Yukimichi Imai, Masahiro Shigeta, Ana Graf, Toru Shirahase, Hyosung Kim, Akifumi Fujii, Joji Mori, Akira Homma
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 1, Iss 1, Pp 163-179 (2011)
Background: As of 2010, the rivastigmine patch was licensed for the treatment of Alzheimer’s disease (AD) in 64 countries. Methods: This 24-week, multicenter, randomized, double-blind, placebo-controlled study evaluated the efficacy, safety and tol
Externí odkaz:
https://doaj.org/article/752c75f6bfca4637bfe80e509795d760
Autor:
Marie‐Emmanuelle Riviere, Raymond Scott Turner, Yihan Sui, Nathalie Laurent, Jessica B. Langbaum, Pilar Cazorla, Javier Ricart, Nicholas Seneca, Angelika Caputo, Eric M. Reiman, Pierre N. Tariot, Ana Graf
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c102594b0179d86891a789fd9e1ff2a5
https://doi.org/10.1002/alz.051287
https://doi.org/10.1002/alz.051287
Autor:
Martin Zalesak, Carolyn Langlois, Eric M. Reiman, Marie-Emmanuelle Riviere, Marie-Laure Rouzade-Dominguez, Jessica B. Langbaum, J. Michael Ryan, Pierre N. Tariot, Fonda Liu, Ana Graf, Rob Lenz, Angelika Caputo, Vissia Viglietta, Suzanne Hendrix, Cristina Lopez Lopez, Ronald G. Thomas
Publikováno v:
Alzheimer's & Dementia : Translational Research & Clinical Interventions
Introduction Alzheimer's disease (AD) pathology, including the accumulation of amyloid beta (Aβ) species and tau pathology, begins decades before the onset of cognitive impairment. This long preclinical period provides an opportunity for clinical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8139e7fba303fa15d706a1cbded55f2b
https://doi.org/10.1016/j.trci.2019.02.005
https://doi.org/10.1016/j.trci.2019.02.005