Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Ana, Elisa Gonçalves"'
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Akademický článek
Efeitos metabólicos de dois protocolos de jejum intermitente em comparação à restrição calórica em ratos
Autor: Geneci Santos de Jesus Reis, Sandra Soares Melo, Daiana Perardt, Ana Paula Dalmagro, Ana Elisa Gonçalves, Priscila Laiz Zimath, Márcia Maria de Souza
Publikováno v: Revista Brasileira de Obesidade, Nutrição e Emagrecimento, Vol 14, Iss 88, Pp 831-842 (2021)
O jejum intermitente (JI) tem sido alvo de investigações cientí­ficas para melhorar a saúde e aumentar a longevidade. O presente estudo teve como objetivo avaliar os efeitos metabólicos de dois protocolos de JI, 6 e 12h, em comparação à rest
Externí odkaz: https://doaj.org/article/d73ea7d2fcf740c99fce91a1ad572d80
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2
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer’s Disease
Autor: Annachiara Gandini, Ana Elisa Gonçalves, Silvia Strocchi, Claudia Albertini, Jana Janočková, Anna Tramarin, Daniela Grifoni, Eleonora Poeta, Ondrej Soukup, Diego Muñoz-Torrero, Barbara Monti, Raimon Sabaté, Manuela Bartolini, Giuseppe Legname, Maria Laura Bolognesi
Publikováno v: ACS Chemical Neuroscience. 13:3314-3329
Alzheimer's disease (AD), the most common type of dementia, currently represents an extremely challenging and unmet medical need worldwide. Amyloid-β (Aβ) and Tau proteins are prototypical AD hallmarks, as well as validated drug targets. Accumulati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120f6def0a91bcbe6be2b2a3c0aece78
https://doi.org/10.1021/acschemneuro.2c00357
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3
DYRK1A inhibitors and perspectives for the treatment of alzheimer's disease
Autor: Márcia, Maria de Souza, Arthur, Ribeiro Cenci, Kerolain, Faoro Teixeira, Valkiria, Machado, Majory Christina, Garcia Mendes Schuler, Ana, Elisa Gonçalves, Ana, Paula Dalmagro, Camila, André Cazarin, Leonardo, Luiz Gomes Ferreira, Aldo, Sena de Oliveira, Adriano, Defini Andricopulo
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background: Alzheimer's disease (AD) is a chronic neurodegenerative disease and the most common form of dementia, especially in the elderly. Due to the increase in life expectancy, in recent years, there has been an excessive growth in the number of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c313bb5b291ef1e270d3e9eb339aa07
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4
Structure–activity relationships of sulfonamides derived from carvacrol and their potential for the treatment of Alzheimer's disease
Autor: Rosendo A. Yunes, Alex R. Medeiros, Thaís Cecília Ribeiro, Aldo Sena de Oliveira, Márcia Maria de Souza, Anacleto Silva de Souza, Leonardo L. G. Ferreira, Adriano D. Andricopulo, Ana Elisa Gonçalves, Marina Corrêa Andreolla
Publikováno v: RSC Med Chem
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Five synthetic sulfonamides derived from carvacrol, a natural product and a small molecule with druglike properties, were evaluated with respect to their effects on the cognitive deficits of animals with streptozotocin (STZ)-induced Alzheimer's disea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8495488dcde8e30de0af9c41222d48
https://doi.org/10.1039/d0md00009d
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5
Phytochemical Analysis and Antinociceptive Properties of Hydroalcoholic Extracts of Aleurites moluccanus Bark
Autor: Luiz G. R. D. Chagas, Simone Reichert, Christiane Meyre-Silva, Valdir Cechinel-Filho, Ana Elisa Gonçalves, Ivania T. A. Schuquel, Marcelo Tomczak, Márcia Maria de Souza
Publikováno v: Planta medica. 87(10-11)
Aleurites moluccanus is used in folk medicine to treat many diseases including pain and inflammatory processes in general. Considering the potential of the leaf extract, evidenced in a previous study, the present study investigates the antinociceptiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bd87f89481f1e4f59732746363aeb2
https://pubmed.ncbi.nlm.nih.gov/34034350
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6
Akademický článek
Instituições e nível de renda: Uma abordagem empírica para os municípios paranaenses
Autor: Ana Elisa Gonçalves Pereira, Luciano Nakabashi, Márcio A. Salvato
Publikováno v: Nova Economia, Vol 22, Iss 3 (2013)
O estado do Paraná apresenta uma grande disparidade no nível de renda em seus municípios. A diferença entre os municípios com o maior e o menor PIB por trabalhador no início do milênio, segundo dados do IBGE (2000), era superior a 700%. Uma ex
Externí odkaz: https://doaj.org/article/e94a59dc52884f96bd945cf151bdeb34
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7
2',6'-dihydroxy-4'-methoxy dihydrochalcone improves the cognitive impairment of Alzheimer's disease: a structure-activity relationship study
Autor: Adriano D. Andricopulo, Leticia C. Lacava, María J. Dávila-Rodríguez, Ângela Malheiros, Ana Elisa Gonçalves, David L. Palomino-Salcedo, Leonardo L. G. Ferreira, Aldo Sena de Oliveira, Lara de França, Camila A. Casarin, Márcia Maria de Souza
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background: Chalcones and dihydrochalcones present potent inhibition of acetylcholinesterase, currently considered the most efficient approach for symptomatic treatment of Alzheimer’s disease. Objective: The present study aimed to explore the poten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b5f8db31606740eff07e74281f52ed3
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9
Trading for Bailouts
Autor: Ahnert, Toni, Machado, Caio, Pereira, Ana Elisa Gonçalves
"In times of high uncertainty, governments often implement interventions such as bailouts to financial institutions. To use public resources efficiently and to avoid major spillovers to the rest of the economy, policy-makers try to identify which ins
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d06f36ace045e787efe45ad4a609ae
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10
Molecular Hybridization as a Tool for Designing Multitarget Drug Candidates for Complex Diseases
Autor: Ana Elisa Gonçalves, Maria Laura Bolognesi, Claudia Albertini, Viktoriya Ivasiv, Michele Rossi
Publikováno v: Current topics in medicinal chemistry. 19(19)
Molecular hybridization is a well-exploited medicinal chemistry strategy that aims to combine two molecules (or parts of them) in a new, single chemical entity. Recently, it has been recognized as an effective approach to design ligands able to modul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a1dc90049aaa5b337d61350ba4c54b
https://pubmed.ncbi.nlm.nih.gov/31237210
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