Zobrazeno 1 - 10
of 1 024
pro vyhledávání: '"An-Kwok Wong"'
Autor:
Hengji Chen, Sangeeta Joshi, Amber J. Oberle, An-Kwok Wong, David Shaz, Suman Thapamagar, Laren Tan, James D. Anholm, Paresh C. Giri, Craig Henriquez, Yuh-Chin T. Huang
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Excessive decrease in the flow of the late expiratory portion of a flow volume loop (FVL) or “flattening”, reflects small airway dysfunction. The assessment of the flattening is currently determined by visual inspection by the pulmonary function
Externí odkaz:
https://doaj.org/article/3813fa5367294690a79df5366dd597f8
Autor:
Chun Wai Ng, Kwong-Kwok Wong
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Estrogen receptor (ER) positivity by immunohistochemistry has long been a main selection criterium for breast cancer patients to be treated with endocrine therapy. However, ER positivity might not directly correlate with activated ER signali
Externí odkaz:
https://doaj.org/article/09eacd0448934899945a4560e9f5e124
Autor:
Daniela Tataru, Shahid A. Khan, Roger Hill, Helen Morement, Kwok Wong, Lizz Paley, Mireille B. Toledano
Publikováno v:
JHEP Reports, Vol 6, Iss 3, Pp 100983- (2024)
Background & Aims: While cholangiocarcinoma (CCA) incidence and mortality rates are increasing globally, whether there are regional/temporal variations in these rates for different biliary tract cancer (BTC) subtypes, or whether they differ by sex, s
Externí odkaz:
https://doaj.org/article/0b3b0233b0814ec0983aad13a2469861
Publikováno v:
Molecules, Vol 29, Iss 16, p 3886 (2024)
Artemisinin is a natural sesquiterpene lactone obtained from the traditional Chinese medicinal herb Artemisia annua L. (qinghao). Artemisinin and its derivatives share an unusual endoperoxide bridge and are extensively used for malaria treatment worl
Externí odkaz:
https://doaj.org/article/d07eb98d3cf04d66906117bed1d2aaf1
Autor:
Zigui Chen, Erik Fung, Chun-Kwok Wong, Lowell Ling, Grace Lui, Christopher K. C. Lai, Rita W. Y. Ng, Ryan K. H. Sze, Wendy C. S. Ho, David S. C. Hui, Paul K. S. Chan
Publikováno v:
Metabolites, Vol 14, Iss 7, p 380 (2024)
This prospective study in Hong Kong aimed at identifying prognostic metabolomic and immunologic biomarkers for Coronavirus Disease 2019 (COVID-19). We examined 327 patients, mean age 55 (19–89) years, in whom 33.6% were infected with Omicron and 66
Externí odkaz:
https://doaj.org/article/3387d6e4e62e4bd09db584065dfa88bd
Publikováno v:
Pharmacological Research, Vol 200, Iss , Pp 107072- (2024)
IL-37 is a newly discovered member of the IL-1 cytokine family which plays an important role in regulating inflammation and maintaining physiological homeostasis. IL-37 showed a close relationship with IL-18, another key cytokine in inflammation regu
Externí odkaz:
https://doaj.org/article/e1a25aaf5fab402c9eb403564cc222b7
Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma
Autor:
Jeff Yat-Fai Chung, Philip Chiu-Tsun Tang, Max Kam-Kwan Chan, Vivian Weiwen Xue, Xiao-Ru Huang, Calvin Sze-Hang Ng, Dongmei Zhang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric W-F Lam, David J. Nikolic-Paterson, Ka-Fai To, Hui-Yao Lan, Patrick Ming-Kuen Tang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
TGF-β stimulated tumor-associated neutrophils (TANs) can exert pro-tumoral functions. Here the authors show that Smad3 activation in TANs is associated with an N2-like polarization state and poor outcome in patients with non-small cell lung carcinom
Externí odkaz:
https://doaj.org/article/ba3ca05e7ec94b9aa2d7bbddfdfd4bef
Autor:
Isaac T Cheng, Ho So, Evelyn H Chow, Qihan Wu, Martin Li, Vivian W Hung, Ling Qin, Chun Kwok Wong, Lai Shan Tam
Publikováno v:
Journal of Clinical Rheumatology and Immunology, Vol 24, Iss supp01, Pp 36-37 (2024)
Background: Janus kinases inhibitor (JAKi) is a potent drug in treating patients with rheumatoid arthritis (RA). However, the effect of JAKi on finite structural changes remained uncertain. This study aims to investigate the effect of JAKi on erosion
Externí odkaz:
https://doaj.org/article/a1cb432d11ed4c158aec23071986d2ec
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Autor:
Lowell Ling, Christopher K.C. Lai, Grace Lui, Apple Chung Man Yeung, Hiu Ching Chan, Chung Hon Shawn Cheuk, Adonia Nicole Cheung, Lok Ching Chang, Lok Ching Sandra Chiu, Jack Zhenhe Zhang, Wai-Tat Wong, David S. C. Hui, Chun Kwok Wong, Paul K. S. Chan, Zigui Chen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Longitudinal studies on upper respiratory tract microbiome in coronavirus disease 2019 (COVID-19) without potential confounders such as antimicrobial therapy are limited. The objective of this study is to assess for longitudinal changes in the upper
Externí odkaz:
https://doaj.org/article/f791d26a338f4956af53a62baa13af68