Zobrazeno 1 - 10
of 1 080
pro vyhledávání: '"An Ning Cheng"'
Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?
Autor:
Cheng-Liang Kuo, Ananth Ponneri Babuharisankar, Ying-Chen Lin, Hui-Wen Lien, Yu Kang Lo, Han-Yu Chou, Vidhya Tangeda, Li-Chun Cheng, An Ning Cheng, Alan Yueh-Luen Lee
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-25 (2022)
Abstract The major concept of "oxidative stress" is an excess elevated level of reactive oxygen species (ROS) which are generated from vigorous metabolism and consumption of oxygen. The precise harmonization of oxidative stresses between mitochondria
Externí odkaz:
https://doaj.org/article/108ebfb5f0f6413cb76217a0c97712ef
Autor:
Tsung-Hsien Chuang, An Ning Cheng, Li-Chun Cheng, Cheng-Liang Kuo, Yu Kang Lo, Han-Yu Chou, Chung-Hsing Chen, Yi-Hao Wang, Shih-Jung Cheng, Alan Yueh-Luen Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Mitochondrial Lon is a chaperone and DNA-binding protein that functions in protein quality control and stress response pathways. The level of Lon regulates mitochondrial DNA (mtDNA) metabolism and the production of mitochondrial reactive o
Externí odkaz:
https://doaj.org/article/bb44b7f1cab54c79a2953ed855a5ff74
Autor:
An Ning Cheng, Yu-Kang Lo, Yi-Sheng Lin, Tswen-Kei Tang, Chun-Hua Hsu, John T.-A. Hsu, Alan Yueh-Luen Lee
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 241-251 (2018)
Background: Cdc7-Dbf4 is a conserved serine/threonine kinase that plays an important role in initiation of DNA replication and DNA damage tolerance in eukaryotic cells. Cdc7 has been found overexpressed in human cancer cell lines and tumor tissues, a
Externí odkaz:
https://doaj.org/article/7ad4cb526de04bc380a88d3cff2c32a6
Autor:
Ji-kun Qian, Yuan Ma, Xuan Huang, Xiao-ran Li, Ya-fei Xu, Zi-ying Liu, Yuan Gu, Ke Shen, Liang-jie Tian, Yu-tian Wang, Ning-ning Cheng, Bing-sheng Yang, Kui-yuan Huang, Yu Chai, Guan-qiao Liu, Nai-qian Cui, Song-yun Deng, Nan Jiang, Dao-rong Xu, Bin Yu
Publikováno v:
Journal of Orthopaedic Translation, Vol 49, Iss , Pp 82-95 (2024)
Objective: Osteoclast (OC) over-activation is an important cause of bone loss that is strongly correlated with inflammation. Although the CD163/TWEAK/Fn14 axis has been implicated in several inflammatory pathologies, its contributions to inflammatory
Externí odkaz:
https://doaj.org/article/ea3bc173913947ef852f428164c59585
Autor:
Wen Tao, Xuan Lin, Yuansheng Liu, Li Zeng, Tengfei Ma, Ning Cheng, Jing Jiang, Xiangxiang Zeng, Sisi Yuan
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Accurate prediction of compound-protein interaction (CPI) plays a crucial role in drug discovery. Existing data-driven methods aim to learn from the chemical structures of compounds and proteins yet ignore the conceptual knowledge
Externí odkaz:
https://doaj.org/article/24aaf771feca4dcd967b734074418cf8
Autor:
Kuei-Pin Chung, Chih-Ning Cheng, Yi-Jung Chen, Chia-Lang Hsu, Yen-Lin Huang, Min-Shu Hsieh, Han-Chun Kuo, Ya-Ting Lin, Yi-Hsiu Juan, Kiichi Nakahira, Yen-Fu Chen, Wei-Lun Liu, Sheng-Yuan Ruan, Jung-Yien Chien, Maria Plataki, Suzanne M. Cloonan, Peter Carmeliet, Augustine M. K. Choi, Ching-Hua Kuo, Chong-Jen Yu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Type 2 alveolar epithelial (AT2) cells of the lung are fundamental in regulating alveolar inflammation in response to injury. Impaired mitochondrial long-chain fatty acid β-oxidation (mtLCFAO) in AT2 cells is assumed to aggravate alveolar i
Externí odkaz:
https://doaj.org/article/5afa0e7fd12540ceb61a70ad3c0d6415
Publikováno v:
大数据, Vol 10, Pp 77-88 (2024)
To enhance image clarity and address the difficulties in feature extraction and incomplete haze removal in traditional image dehazing processes, a multi-feature fusion based generative adversarial dehazing network is proposed.The network adopts a gen
Externí odkaz:
https://doaj.org/article/6f9509c6bc3845ecbd3960cc3d03b8a3
Publikováno v:
大数据, Vol 10, Pp 65-81 (2024)
Voice conversion is a research topic in the fields of speech and artificial intelligence.The goal of voice conversion is to change the timbre of speech while preserving the content of the source speech, making it sounds like spoken by the target spea
Externí odkaz:
https://doaj.org/article/23c0b228c49d44d3a0ff96c170675c2f
Publikováno v:
大数据, Vol 10, Pp 62-85 (2024)
Federated learning uses data from multiple participants to collaboratively train global models and has played an increasingly important role in recent years in facilitating inter-firm data collaboration.On the other hand, the federal learning trainin
Externí odkaz:
https://doaj.org/article/16028875b2ea4de5957e1824cd612014
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Gerontology research on anti-aging interventions with drugs could be an answer to age-related diseases, aiming at closing the gap between lifespan and healthspan. Here, we present two methods for assaying chronological lifespan in human cell
Externí odkaz:
https://doaj.org/article/e6061c31863549b8ad5d29645c27f527