Zobrazeno 1 - 10
of 3 402
pro vyhledávání: '"An, Xingcai"'
Autor:
Wang, Jike, Feng, Jianwen, Kang, Yu, Pan, Peichen, Ge, Jingxuan, Wang, Yan, Wang, Mingyang, Wu, Zhenxing, Zhang, Xingcai, Yu, Jiameng, Zhang, Xujun, Wang, Tianyue, Wen, Lirong, Yan, Guangning, Deng, Yafeng, Shi, Hui, Hsieh, Chang-Yu, Jiang, Zhihui, Hou, Tingjun
We propose AMP-Designer, an LLM-based foundation model approach for the rapid design of novel antimicrobial peptides (AMPs) with multiple desired properties. Within 11 days, AMP-Designer enables de novo design of 18 novel candidates with broad-spectr
Externí odkaz:
http://arxiv.org/abs/2407.12296
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract This study aimed to analyze the molecular characteristics of insulin-like growth factor 1 (IGF1) gene in the testes of Tibetan sheep and its role in the testosterone synthesis and cell development. First, we cloned IGF1 gene for bioinformati
Externí odkaz:
https://doaj.org/article/28b093aa4325428c9a178ca8f701e5f1
Autor:
Bin Zheng, Qiuya Li, Laiping Fang, Xiaolu Cai, Yan Liu, Yanhong Duo, Bowen Li, Zhengyu Wu, Boxi Shen, Yang Bai, Shi-Xiang Cheng, Xingcai Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract As a transdermal drug delivery method, microneedles offer minimal invasiveness, painlessness, and precise in-situ treatment. However, current microneedles rely on passive diffusion, leading to uncontrollable drug penetration. To overcome thi
Externí odkaz:
https://doaj.org/article/702311612f5b4d3e8482b99dc7240b18
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Nanocarriers (NCs) play a crucial role in delivering theranostic agents to tumors, making them a pivotal focus of research. However, the persistently low delivery efficiency of engineered NCs has been a significant challenge in the advanceme
Externí odkaz:
https://doaj.org/article/e221b7c83e504c5c96065ce6f89273e0
Autor:
Bingchuan Liu, Xingcai Li, Zhengguang Wang, Zhuo Chen, Fang Zhou, Zhongwei Yang, Guojin Hou, Min Liu, Kai Song, Caimei Wang, Yun Tian, Jinjiao Li
Publikováno v:
Chinese Medical Journal, Vol 137, Iss 20, Pp 2515-2517 (2024)
Externí odkaz:
https://doaj.org/article/7a20baa146ad47c397d26786bb8909ae
Publikováno v:
陆军军医大学学报, Vol 46, Iss 16, Pp 1897-1905 (2024)
Objective To establish an artificial intelligence (AI) diagnostic model for the histopathologic diagnosis of extramammary Paget's disease (EMPD) and to evaluate its efficiency for the diagnosis and differential diagnosis of EMPD. Methods All non-tumo
Externí odkaz:
https://doaj.org/article/68e79cbb60704d35b4d0ddcdb7ba3961
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Limited treatment options and poor prognosis present significant challenges in the treatment of lung squamous cell carcinoma (LUSC). Disulfidptosis impacts cancer progression and prognosis. We developed a prognostic signature using disulfidp
Externí odkaz:
https://doaj.org/article/da93a4d0e18e4466a29cb32a8dd0a940
Autor:
Bingchuan Liu, Liwei Wang, Xingcai Li, Zhuo Chen, Guojin Hou, Fang Zhou, Caimei Wang, Yun Tian
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Clinical repair of critical-sized bone defects (CBDs) in the tibial diaphysis presents numerous challenges, including inadequate soft tissue coverage, limited blood supply, high load-bearing demands, and potential deformities. Thi
Externí odkaz:
https://doaj.org/article/c0ef147c7be2458f8cfd2ab9220cf7a9
Autor:
Haotian Xu, Yue Zheng, Jiaxi Wu, Ruirui Zhang, Qingyun Zhao, Sixian Chen, Wenyi Peng, Dunyu Cai, Yihong Gao, Xingcai Chen, Deqing Li, Shengyi yuan, Gang Li, Aruo Nan
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Lung cancer is the primary cause of cancer-related death worldwide, and its global incidence and mortality rates remain high. The differential expression of circular RNAs (circRNAs) can affect the development of cancer, but the mechanisms by
Externí odkaz:
https://doaj.org/article/f707fa96fd3c4934be6482623088bfd3
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background The treatment of infected bone defects remains a clinical challenge. With the development of three-dimensional printing technology, three-dimensional printed implants have been used for defect reconstruction. The aim of this study
Externí odkaz:
https://doaj.org/article/1206b67170fb4837807894c7088f05be