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Akademický článek

Parkinson’s disease is associated with clonal hematopoiesis with TET2 mutation

Autor: Kyung Ah Woo, Han-Joon Kim, Chan Young Lee, Jung Hwan Shin, Choonghyun Sun, Hogune Im, Hongyul An, Jiwoo Lim, Su-Yeon Choi, Youngil Koh, Beomseok Jeon

Publikováno v: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-7 (2024)

Abstract Clonal hematopoiesis of indeterminate potential (CHIP), a premalignant expansion of mutated hematopoietic stem cells, is linked to immune alterations. Given the role of neuroinflammation and immune dysfunction in Parkinson’s disease (PD),

Externí odkaz: https://doaj.org/article/d5c63421b882415bbe899cbe86022d4c

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Akademický článek

Clonal Hematopoiesis of Indeterminate Potential Is Associated with Current Smoking Status and History of Exacerbation in Patients with Chronic Obstructive Pulmonary Disease

Autor: Jung-Kyu Lee, Hongyul An, Youngil Koh, Chang-Hoon Lee

Publikováno v: Tuberculosis and Respiratory Diseases, Vol 87, Iss 3, Pp 309-318 (2024)

Background There is limited data regarding the clinical outcomes of clonal hematopoiesis of indeterminate potential (CHIP) in patients with chronic obstructive pulmonary disease (COPD). This study aimed to evaluate the clinical significance of CHIP a

Externí odkaz: https://doaj.org/article/fe692d53cf1c4c84be899b114eb24dc6

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Akademický článek

Pre-operative clonal hematopoiesis is related to adverse outcome in lung cancer after adjuvant therapy

Autor: Jae Kwang Yun, Sugyeong Kim, Hongyul An, Geun Dong Lee, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Sehoon Choi, Youngil Koh

Publikováno v: Genome Medicine, Vol 15, Iss 1, Pp 1-11 (2023)

Abstract Background Clonal hematopoiesis (CH) frequently progresses after chemotherapy or radiotherapy. We evaluated the clinical impact of preoperative CH on the survival outcomes of patients with non-small cell lung cancer (NSCLC) who underwent sur

Externí odkaz: https://doaj.org/article/065f322994904423957a1de576f48fc0

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Akademický článek

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Akademický článek

Interplay between chronic inflammation and clonal haematopoiesis of indeterminate potential in Behçet’s disease

Autor: Jihye Park, Hongyul An, Jiwoo Lim, I Seul Park, Mi Hyun Kim, Ji Hyung Kim, Seung Won Kim, Young Il Koh, Eun Young Lee, Jae Hee Cheon

Publikováno v: Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-7 (2023)

Abstract Background Clonal haematopoiesis of indeterminate potential (CHIP) is a predisposition to haematological malignancy whose relationship with chronic inflammatory diseases, such as cardiovascular diseases, has been highlighted. Here, we aimed

Externí odkaz: https://doaj.org/article/21f3545209d34401a4d30ea997eb956e

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