Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Amyn M. Rojiani"'
Autor:
Nikhil S. Sahajpal, Ashis K. Mondal, Sudha Ananth, Allan Njau, Kimya Jones, Pankaj Ahluwalia, Eesha Oza, Ted M. Ross, Vamsi Kota, Arvind Kothandaraman, Sadanand Fulzele, Madhuri Hegde, Alka Chaubey, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The COVID-19 pandemic has resulted in significant diversion of human and material resources to COVID-19 diagnostics, to the extent that influenza viruses and co-infection in COVID-19 patients remains undocumented and pose serious public-heal
Externí odkaz:
https://doaj.org/article/159ea4b76fc2461b8641e49ad87f0aca
Autor:
Pankaj Ahluwalia, Ashis K. Mondal, Meenakshi Ahluwalia, Nikhil S. Sahajpal, Kimya Jones, Yasmeen Jilani, Gagandeep K. Gahlay, Amanda Barrett, Vamsi Kota, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Cancer Medicine, Vol 11, Iss 6, Pp 1573-1586 (2022)
Abstract Understanding the complex tumor microenvironment is key to the development of personalized therapies for the treatment of cancer including colorectal cancer (CRC). In the past decade, significant advances in the field of immunotherapy have c
Externí odkaz:
https://doaj.org/article/ac4838910f06485e931a364e4f27103c
Autor:
Goldin John, Nikhil Shri Sahajpal, Ashis K. Mondal, Sudha Ananth, Colin Williams, Alka Chaubey, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 845-867 (2021)
This review discusses the current testing methodologies for COVID-19 diagnosis and explores next-generation sequencing (NGS) technology for the detection of SARS-CoV-2 and monitoring phylogenetic evolution in the current COVID-19 pandemic. The review
Externí odkaz:
https://doaj.org/article/faaa7b536ed64b029c1b71d5373414a9
Autor:
Pankaj Ahluwalia, Meenakshi Ahluwalia, Ashis K. Mondal, Nikhil Sahajpal, Vamsi Kota, Mumtaz V. Rojiani, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Complex interactions in tumor microenvironment between ECM (extra-cellular matrix) and cancer cell plays a central role in the generation of tumor supportive microenvironment. In this study, the expression of ECM-related genes was explored f
Externí odkaz:
https://doaj.org/article/f621f9d36b0a43ddb286cec1169bbb0b
Autor:
Nikhil Shri Sahajpal, Chi-Yu Jill Lai, Alex Hastie, Ashis K. Mondal, Siavash Raeisi Dehkordi, Caspar I. van der Made, Olivier Fedrigo, Farooq Al-Ajli, Sawan Jalnapurkar, Marta Byrska-Bishop, Rashmi Kanagal-Shamanna, Brynn Levy, Maximilian Schieck, Thomas Illig, Silviu-Alin Bacanu, Janet S. Chou, Adrienne G. Randolph, Amyn M. Rojiani, Michael C. Zody, Catherine A. Brownstein, Alan H. Beggs, Vineet Bafna, Erich D. Jarvis, Alexander Hoischen, Alka Chaubey, Ravindra Kolhe
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103760- (2022)
Summary: Impressive global efforts have identified both rare and common gene variants associated with severe COVID-19 using sequencing technologies. However, these studies lack the sensitivity to accurately detect several classes of variants, especia
Externí odkaz:
https://doaj.org/article/6522ade0da724f48b8c81dc340d11287
Autor:
Wei Xiao, Pankaj Ahluwalia, Lan Wang, John Howard, Ravindra Kolhe, Amyn M. Rojiani, Mumtaz V. Rojiani
Publikováno v:
Cells, Vol 11, Iss 19, p 3036 (2022)
The development of chemoresistance remains a significant barrier to treating NSCLC. Alteration of cancer cell metabolism is an important mechanism for chemoresistance. This study explored the role of aberrant metabolism in TIMP-1-mediated chemoresist
Externí odkaz:
https://doaj.org/article/4e3372b0211149e4a802fd7493c8f3f1
Autor:
Nikhil S. Sahajpal PhD, Ashis K. Mondal PhD, Sudha Ananth MS, Allan Njau MD, Sadanand Fulzele PhD, Pankaj Ahaluwalia PhD, Alka Chaubey PhD, Madhuri Hegde PhD, Amyn M. Rojiani MD, PhD, Ravindra Kolhe MD, PhD
Publikováno v:
Academic Pathology, Vol 8 (2021)
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2, led to unprecedented demands assigned to clinical diagnostic laboratories worldwide, forcing them to make significant changes to their regular workflow as they adapted
Externí odkaz:
https://doaj.org/article/652ea767afe64fb6adfff72e16ac47df
Autor:
Pankaj Ahluwalia, Kumar Vaibhav, Meenakshi Ahluwalia, Ashis K. Mondal, Nikhil Sahajpal, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
SARS-CoV-2 is the cause of a recent pandemic that has led to more than 3 million deaths worldwide. Most individuals are asymptomatic or display mild symptoms, which raises an inherent question as to how does the immune response differs from patients
Externí odkaz:
https://doaj.org/article/a2a78a5456b840a1bde9c569e8e2c219
Autor:
Theresa A. Boyle, Ashis K. Mondal, Daryoush Saeed-Vafa, Sudha Ananth, Pankaj Ahluwalia, Ravi Kothapalli, Alka Chaubey, Evans Roberts, Dahui Qin, Anthony M. Magliocco, Amyn M. Rojiani, Ravindra Kolhe
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
We describe the clinical validation of a targeted DNA and RNA-based next-generation sequencing (NGS) assay at two clinical molecular diagnostic laboratories. This assay employs simultaneous DNA and RNA analysis of all coding exons to detect small var
Externí odkaz:
https://doaj.org/article/8abacc7ff1624b0895b2f5e3cc444080
Autor:
Cindy B. McCloskey MD, Kristen Johnson PhD, Mark Brissette MD, Richard Conran MD, PhD, JD, John Childs MD, Melissa George DO, Dita Gratzinger MD, PhD, Victor G. Prieto MD, PhD, Amyn M. Rojiani MD, PhD, Irene Shyu MD, Charles Timmons MD, PhD, Robert Hoffman MD
Publikováno v:
Academic Pathology, Vol 7 (2020)
The SARS-CoV-2 pandemic has highlighted the crucial role of pathologists in the health care system at a time of significant decline in the number of US medical students matching to pathology residency positions. To understand this decline, a national
Externí odkaz:
https://doaj.org/article/49a31158b2d84a0ea1ca10b6f24e744e