Zobrazeno 1 - 10
of 3 586
pro vyhledávání: '"Amyloid-peptide"'
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Recent reports suggest that amyloid beta (Aβ) peptides can exhibit prion-like pathogenic properties. Transmission of Aβ peptide and the development of associated pathologies after surgeries with contaminated instruments and intr
Externí odkaz:
https://doaj.org/article/138af1cc6e0145c7ac61284247af3f6e
Autor:
Irina S. Milentyeva, Anna D. Vesnina, Anastasiya M. Fedorova, Elena V. Ostapova, Timothy A. Larichev
Publikováno v:
Техника и технология пищевых производств, Vol 53, Iss 4, Pp 754-765 (2023)
Polyphenols are potential neuroprotectors that increase lifespan and slow down aging. Red clover (Trifolium pratense L.) is a promising source of biologically active substances. Its extracts contain biochanin A and chlorogenic acid. This research use
Externí odkaz:
https://doaj.org/article/c3757d9a720f43b0bb9c62559c5382b1
Autor:
Amanda Gomes da Silva, Mariana da Mata Alves, Admilson Aparecido da Cunha, Giovanna Arruda Caires, Irina Kerkis, Hugo Vigerelli, Juliana Mozer Sciani
Publikováno v:
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 29 (2023)
Abstract Background: Echinometra lucunter is a sea urchin commonly found on America’s rocky shores. Its coelomic fluid contains molecules used for defense and biological processes, which may have therapeutic potential for the treatment of amyloid-b
Externí odkaz:
https://doaj.org/article/e29933ae740d4383bf68984a169ab097
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this study, a series of potential ligands for the treatment of AD were synthesised and characterised as novel harmine derivatives modified at position 9 with benzyl piperazinyl. In vitro studies revealed that the majority of the derivatives exhibi
Externí odkaz:
https://doaj.org/article/b10ce62007d84b54a1f13a7f9b53cf07
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Parkinson’s disease (PD) is a predominantly idiopathic pathological condition characterized by protein aggregation phenomena, whose main component is alpha-synuclein. Although the main risk factor is ageing, numerous evidence points to the role of
Externí odkaz:
https://doaj.org/article/e532a0fa4b89453f972003bfe6e11eee
Publikováno v:
Folia Neuropathologica, Vol 61, Iss 1, Pp 37-46 (2023)
Externí odkaz:
https://doaj.org/article/debde6cb9eef4cccaef692a57b043749
Autor:
Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki‐Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun‐Ichiro Oka
Publikováno v:
Neuropsychopharmacology Reports, Vol 42, Iss 4, Pp 492-501 (2022)
Abstract Aim We previously reported that oxytocin, a peptide hormone, can reverse the β‐amyloid peptide (25–35) (Aβ25–35)‐induced impairments of the murine hippocampal synaptic plasticity. In this study, we examined the effects of oxytocin
Externí odkaz:
https://doaj.org/article/ff4dd2c485744413a1596cf3f380bc36
Akademický článek
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Autor:
Jozef Nahalka
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 8, Pp 3533-3551 (2022)
Alzheimer’s disease is a very complex disease and better explanations and models are needed to understand how neurons are affected and microglia are activated. A new model of Alzheimer’s disease is presented here, the β-amyloid peptide is consid
Externí odkaz:
https://doaj.org/article/311b17daaf47496289b6f6c585df2486
Publikováno v:
Food Science and Human Wellness, Vol 11, Iss 3, Pp 483-493 (2022)
ABSTRACT: Alzheimer’s disease (AD) is the most common neurodegenerative disease characterized by cognitive decline and memory impairment. Many lines of evidence indicate that excessive β-amyloid peptide (Aβ) generation and aggregation play pivota
Externí odkaz:
https://doaj.org/article/3fd9ec33e25d4c46ad748f3b8dfcb29d