Molecular dynamics simulations to explore the binding mode between the amyloid-β protein precursor (APP) and adaptor protein Mint2.

Autor: Wang, Min^1,2 (AUTHOR) wangm@cust.edu.cn, Liu, Kaifeng³ (AUTHOR)

Publikováno v: Scientific Reports. 4/4/2024, Vol. 14 Issue 1, p1-12. 12p.

Anti‐LINGO‐1 antibody treatment alleviates cognitive deficits and promotes maturation of oligodendrocytes in the hippocampus of APP/PS1 mice.

Autor: Yang, Hao, Jiang, Lin, Zhang, Yi, Liang, Xin, Tang, Jing, He, Qi, Luo, Yan‐Min, Zhou, Chun‐Ni, Zhu, Lin, Zhang, Shan‐Shan, Xiao, Kai, Zhu, Pei‐Lin, Wang, Jin, Li, Yue, Chao, Feng‐Lei, Tang, Yong

Publikováno v: Journal of Comparative Neurology; Jul2022, Vol. 530 Issue 10, p1606-1621, 16p

Anti‐LINGO‐1 antibody treatment alleviates cognitive deficits and promotes maturation of oligodendrocytes in the hippocampus of APP/PS1 mice

Autor: Hao Yang, Lin Jiang, Yi Zhang, Xin Liang, Jing Tang, Qi He, Yan‐Min Luo, Chun‐Ni Zhou, Lin Zhu, Shan‐Shan Zhang, Kai Xiao, Pei‐Lin Zhu, Jin Wang, Yue Li, Feng‐Lei Chao, Yong Tang

Publikováno v: Journal of Comparative Neurology. 530:1606-1621

Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO-1), a negative regulator of oligodendrocyte differentiation and myelination, is associated with cognitive function, and its expression is highly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faafaa82a674ae45686dbac58f7ddb9a
https://doi.org/10.1002/cne.25299

Decrease in p3-Alcβ37 and p3-Alcβ40, products of Alcadein β generated by γ-secretase cleavages, in aged monkeys and patients with Alzheimer's disease.

Autor: Hata S; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Omori C; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.; Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Japan., Kimura A; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Saito H; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Kimura N; Section of Cell Biology and Pathology, Department of Alzheimer's Disease Research, Center for Development of Advanced Medicine for Dementia, National Center for Geriatrics and Gerontology, Obu, Japan.; Tsukuba Primate Research Center, National Institutes of Biomedical Innovation, Health and Nutrition, Tsukuba, Japan., Gupta V; Centre of Excellence for Alzheimer's Disease Research and Care, Sir James McCusker Alzheimer's Disease Research Unit, Edith Cowan University, Joodalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Co-operative Research Centre for Mental Health, Carlton, VIC, Australia., Pedrini S; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Co-operative Research Centre for Mental Health, Carlton, VIC, Australia., Hone E; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Co-operative Research Centre for Mental Health, Carlton, VIC, Australia., Chatterjee P; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, Macquarie University, Sydney, NSW, Australia., Taddei K; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Kasuga K; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Ikeuchi T; Department of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan., Waragai M; Department of Neurology, Higashi Matsudo Municipal Hospital, Matsudo, Japan., Nishimura M; Molecular Neuroscience Research Center, Shiga University of Medical Science, Otsu, Japan., Hu A; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Nakaya T; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Meijer L; ManRos Therapeutics, Centre de Perharidy, Roscoff, Bretagne, France., Maeda M; Immuno-Biological Laboratories Co., Ltd. (IBL), Fujioka, Japan., Yamamoto T; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.; Department of Molecular Neurobiology, Faculty of Medicine, Kagawa University, Miki-cho, Kagawa, Japan., Masters CL; Neurodegeneration Division, The Florey Institute, The University of Melbourne, Parkville, VIC, Australia., Rowe CC; Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, VIC, Australia., Ames D; National Ageing Research Institute, Parkville, VIC, Australia.; Academic Unit for Psychiatry of Old age, St. George's Hospital, The University of Melbourne, Parkville, VIC, Australia., Yamamoto K; Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Japan., Martins RN; Centre of Excellence for Alzheimer's Disease Research and Care, Sir James McCusker Alzheimer's Disease Research Unit, Edith Cowan University, Joodalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Co-operative Research Centre for Mental Health, Carlton, VIC, Australia.; Department of Biomedical Sciences, Faculty of Medical and Health Sciences, Macquarie University, Sydney, NSW, Australia., Gandy S; Mount Sinai Center for Cognitive Health and NFL Neurological Care, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Suzuki T; Laboratory of Neuroscience, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.

Publikováno v: Alzheimer's & dementia (New York, N. Y.) [Alzheimers Dement (N Y)] 2019 Nov 07; Vol. 5, pp. 740-750. Date of Electronic Publication: 2019 Nov 07 (Print Publication: 2019).