Zobrazeno 1 - 10
of 5 746
pro vyhledávání: '"Amyloid fibrils"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Self-assembly is a key process in living systems—from the microscopic biological level (e.g. assembly of proteins into fibrils within biomolecular condensates in a human cell) through to the macroscopic societal level (e.g. assembly of hum
Externí odkaz:
https://doaj.org/article/3110a6c3e15c4321affd842af3837d65
Publikováno v:
East European Journal of Physics, Iss 3, Pp 479-483 (2024)
The present study employs molecular dynamics simulations to investigate the interactions between quercetin, amyloid fibrils, and POPC lipid bilayers. The results demonstrate that quercetin does not significantly affect the molecular organization of t
Externí odkaz:
https://doaj.org/article/2121578ddc104a12ae3e9575e1caf04f
Publikováno v:
East European Journal of Physics, Iss 2, Pp 463-469 (2024)
The elucidation of interactions between functional proteins and amyloid fibrils is crucial for understanding the molecular basis of amyloid diseases, which are characterized by protein misfolding and aggregation. Polyphenols, due to their diverse bio
Externí odkaz:
https://doaj.org/article/5b3e724cef524457999bc95e80f9f451
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 10, Pp 105982- (2024)
Protein fibrillation is a crucial process in the onset of several neurodegenerative and retinal disorders due to the formation of cytotoxic species. Because of their capacity to prevent protein aggregation, small molecules have the potential to be ap
Externí odkaz:
https://doaj.org/article/7370ff5dcb2542e9a5e5dc95a5b78ebb
Publikováno v:
Bioresources and Bioprocessing, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Amyloid fibrils derived from different proteins have been proved as a promising material for adsorption of various pollutants from wastewater, which showed advantages of low cost and eco-friendliness. However, most of the amyloid fibrils der
Externí odkaz:
https://doaj.org/article/d12aeba8a75a4682b6673b07be3a549a
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 4, Iss 1, Pp 72-81 (2024)
Carbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in neurological disorders. Carbon nanotubes owing to their fascinating properties have the potenti
Externí odkaz:
https://doaj.org/article/08537159449047178cc13039ad71f510
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Manoj Madheswaran, Nataliia Ventserova, Gianluca D’Abrosca, Giulia Salzano, Luigi Celauro, Federico Angelo Cazzaniga, Carla Isernia, Gaetano Malgieri, Fabio Moda, Luigi Russo, Giuseppe Legname, Roberto Fattorusso
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 9916 (2024)
The pathological process of prion diseases implicates that the normal physiological cellular prion protein (PrPC) converts into misfolded abnormal scrapie prion (PrPSc) through post-translational modifications that increase β-sheet conformation. We
Externí odkaz:
https://doaj.org/article/d55ca9dbad8b4a0f8fda269a656b62ff
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background Mutations of the gene TMEM106B are risk factors for diverse neurodegenerative diseases. Previous understanding of the underlying mechanism focused on the impairment of lysosome biogenesis caused by TMEM106B loss-of-function. Howev
Externí odkaz:
https://doaj.org/article/70dd9d4ae954452ebb9e5881d8d99b55