Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amyloid beta-Peptides/blood"'
Autor:
Lutz Frölich, Kaj Blennow, Karen Meersmans, Kristel Sleegers, Cristina Legido-Quigley, Mara ten Kate, Tommi Suvitaival, Julius Popp, Frederik Barkhof, Sarah Westwood, Tahmina Ahmad, Petra Proitsi, Jill C. Richardson, Magda Tsolaki, José Luis Molinuevo, Mikel Tainta, Alison L. Baird, Pablo Martinez-Lage, Philip Scheltens, Abdul Hye, Yvonne Freund-Levi, Lorena Rami, Adnan Ali, Stephanie J.B. Vos, Frans R.J. Verhey, Stuart G. Snowden, Rik Vandenberghe, Valerija Dobricic, Charlotte E. Teunissen, Pieter Jelle Visser, Petronella Kettunen, Min Kim, Peter Johannsen, Régis Bordet, David J. Merkler, Nicholas J. Ashton, Alberto Lleó, Henrik Zetterberg, Gwendoline Peyratout, Alejo J. Nevado-Holgado, Anders Wallin, Sebastiaan Engelborghs, Olivier Blin, Johannes Streffer, Isabel Sala, Isabelle Bos, Simon Lovestone, Ellen De Roeck, Lars Bertram, Silvy Gabel, Giovanni B. Frisoni
Publikováno v:
Alzheimer's & dementia, vol. 15, no. 6, pp. 817-827
Kim, M, Snowden, S, Suvitaival, T, Ali, A, Merkler, D J, Ahmad, T, Westwood, S, Baird, A, Proitsi, P, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S, Vandenberghe, R, Teunissen, C, ten Kate, M, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, de Roeck, E, Sleegers, K, Bordet, R G, Rami, L, Kettunen, P, Tsolaki, M, Verhey, F, Sala, I, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Engelborghs, S, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Barkhof, F, Ashton, N, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort ', Alzheimer's and Dementia, vol. 15, no. 6, pp. 817-827 . https://doi.org/10.1016/j.jalz.2019.03.004
Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2019, 15 (6), pp.817-827. ⟨10.1016/j.jalz.2019.03.004⟩
Alzheimer's & Dementia
Alzheimer's & Dementia, 2019, 15 (6), pp.817-827. ⟨10.1016/j.jalz.2019.03.004⟩
Alzheimer's and Dementia, 15(6), 817-827. Elsevier
Alzheimers & Dementia
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's & dementia
Kim, M, Snowden, S, Suvitaival, T, Ali, A, Merkler, D J, Ahmad, T, Westwood, S, Baird, A, Proitsi, P, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S, Vandenberghe, R, Teunissen, C, Ten Kate, M, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, De Roeck, E, Sleegers, K, Bordet, R, Rami, L, Kettunen, P, Tsolaki, M, Verhey, F, Sala, I, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Engelborghs, S, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Barkhof, F, Ashton, N, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort ', Alzheimer's & Dementia, vol. 15, no. 6, pp. 817-827 . https://doi.org/10.1016/j.jalz.2019.03.004
Alzheimer's & Dementia, Vol. 15, No 6 (2019) pp. 817-827
Alzheimer's & Dementia, 15(6), 817-827. Elsevier Science
Kim, M, Snowden, S, Suvitaival, T, Ali, A, Merkler, D J, Ahmad, T, Westwood, S, Baird, A, Proitsi, P, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S, Vandenberghe, R, Teunissen, C, ten Kate, M, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, de Roeck, E, Sleegers, K, Bordet, R G, Rami, L, Kettunen, P, Tsolaki, M, Verhey, F, Sala, I, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Engelborghs, S, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Barkhof, F, Ashton, N, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort ', Alzheimer's and Dementia, vol. 15, no. 6, pp. 817-827 . https://doi.org/10.1016/j.jalz.2019.03.004
Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2019, 15 (6), pp.817-827. ⟨10.1016/j.jalz.2019.03.004⟩
Alzheimer's & Dementia
Alzheimer's & Dementia, 2019, 15 (6), pp.817-827. ⟨10.1016/j.jalz.2019.03.004⟩
Alzheimer's and Dementia, 15(6), 817-827. Elsevier
Alzheimers & Dementia
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Alzheimer's & dementia : the journal of the Alzheimer's Association
Alzheimer's & dementia
Kim, M, Snowden, S, Suvitaival, T, Ali, A, Merkler, D J, Ahmad, T, Westwood, S, Baird, A, Proitsi, P, Nevado-Holgado, A, Hye, A, Bos, I, Vos, S, Vandenberghe, R, Teunissen, C, Ten Kate, M, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, De Roeck, E, Sleegers, K, Bordet, R, Rami, L, Kettunen, P, Tsolaki, M, Verhey, F, Sala, I, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Engelborghs, S, Frisoni, G B, Molinuevo, J L, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Barkhof, F, Ashton, N, Blennow, K, Zetterberg, H, Streffer, J, Visser, P J, Lovestone, S & Legido-Quigley, C 2019, ' Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort ', Alzheimer's & Dementia, vol. 15, no. 6, pp. 817-827 . https://doi.org/10.1016/j.jalz.2019.03.004
Alzheimer's & Dementia, Vol. 15, No 6 (2019) pp. 817-827
Alzheimer's & Dementia, 15(6), 817-827. Elsevier Science
Introduction: A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes clinical symptom onset, we set out to test whether metabolites in blood associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7566425c78fd543af6a31fa0be1388dc
https://serval.unil.ch/notice/serval:BIB_7B445915312D
https://serval.unil.ch/notice/serval:BIB_7B445915312D
Autor:
Frederik Barkhof, Richard Dobson, Sebastiaan Engelborghs, Kristel Sleegers, Julius Popp, Anders Wallin, Rik Vandenberghe, Simon Lovestone, Giovanni B. Frisoni, Alberto Lleó, Lars Bertram, Alison L. Baird, Philip Scheltens, Cristina Legido-Quigley, Mara ten Kate, Pieter Jelle Visser, Pablo Martinez-Lage, Stephanie J.B. Vos, Christine Van Broeckhoven, José Luis Molinuevo, Henrik Zetterberg, Johannes Streffer, Isabelle Bos
Publikováno v:
Alzheimer's research & therapy
Alzheimer's Research & Therapy
Alzheimers Research & Therapy
Alzheimer's Research & Therapy, 10:64. BioMed Central Ltd
Alzheimer's Research and Therapy, Vol. 10, No 1 (2018) P. 64
Bos, I, Vos, S, Vandenberghe, R, Scheltens, P, Engelborghs, S, Frisoni, G, Molinuevo, J L, Wallin, A, Lleó, A, Popp, J, Martinez-Lage, P, Baird, A, Dobson, R, Legido-Quigley, C, Sleegers, K, Van Broeckhoven, C, Bertram, L, Ten Kate, M, Barkhof, F, Zetterberg, H, Lovestone, S, Streffer, J & Visser, P J 2018, ' The EMIF-AD Multimodal Biomarker Discovery study : design, methods and cohort characteristics ', Alzheimer's Research & Therapy, vol. 10, no. 1, pp. 64 . https://doi.org/10.1186/s13195-018-0396-5
Alzheimer's Research & Therapy, 10(1). BioMed Central
Alzheimer's research & therapy, vol. 10, no. 1, pp. 64
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2018)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Alzheimer's Research & Therapy
Alzheimers Research & Therapy
Alzheimer's Research & Therapy, 10:64. BioMed Central Ltd
Alzheimer's Research and Therapy, Vol. 10, No 1 (2018) P. 64
Bos, I, Vos, S, Vandenberghe, R, Scheltens, P, Engelborghs, S, Frisoni, G, Molinuevo, J L, Wallin, A, Lleó, A, Popp, J, Martinez-Lage, P, Baird, A, Dobson, R, Legido-Quigley, C, Sleegers, K, Van Broeckhoven, C, Bertram, L, Ten Kate, M, Barkhof, F, Zetterberg, H, Lovestone, S, Streffer, J & Visser, P J 2018, ' The EMIF-AD Multimodal Biomarker Discovery study : design, methods and cohort characteristics ', Alzheimer's Research & Therapy, vol. 10, no. 1, pp. 64 . https://doi.org/10.1186/s13195-018-0396-5
Alzheimer's Research & Therapy, 10(1). BioMed Central
Alzheimer's research & therapy, vol. 10, no. 1, pp. 64
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-9 (2018)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Background There is an urgent need for novel, noninvasive biomarkers to diagnose Alzheimer’s disease (AD) in the predementia stages and to predict the rate of decline. Therefore, we set up the European Medical Information Framework for Alzheimer’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6eedcdfeb2a25dcc0295bf4142b693
http://hdl.handle.net/10852/62181
http://hdl.handle.net/10852/62181
Autor:
Frank Jessen, Jan Philipp Bach, Judith Alferink, Isaac Melamed, Jens Wiltfang, Stefan Haag, Yaroslav Winter, Jerome Goldstein, Richard Dodel, Martin R. Farlow, Ralph W. Richter, Kaj Blennow, Stefan Förster, Katharina Buerger, Michael Jacoby, Julius Popp, James C. Stevens, Markus Otto, Frederik Barkhof, Piero Antuono, Peter Bartenstein, Stefan Wietek, Axel Rominger
Publikováno v:
Dodel, R, Rominger, A, Bartenstein, P, Barkhof, F, Blennow, K, Forster, S, Winter, Y, Bach, J P, Popp, J, Alferink, J, Wiltfang, J, Buerger, K, Otto, M, Antuono, P, Jacoby, M, Richter, R, Stevens, J, Melamed, I, Goldstein, J, Haag, S, Wietek, S, Farlow, M & Jessen, F 2013, ' Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial ', Lancet Neurology, vol. 12, no. 3, pp. 233-243 . https://doi.org/10.1016/S1474-4422(13)70014-0
The lancet / Neurology 12(3), 233-243 (2013). doi:10.1016/S1474-4422(13)70014-0
Lancet Neurology, 12(3), 233-243. Lancet Publishing Group
The Lancet Neurology, Vol. 12, No 3 (2013) pp. 233-243
The lancet
Lancet Neurology, 12(3), 233-243. Lancet Publishing Group
The Lancet Neurology, Vol. 12, No 3 (2013) pp. 233-243
Summary Background Three small trials suggest that intravenous immunoglobulin can affect biomarkers and symptoms of mild-to-moderate Alzheimer's disease. We tested the safety, effective dose, and infusion interval of intravenous immunoglobulin in suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14627614a4a57861ef6fa044cec2b338
https://research.vumc.nl/en/publications/baa42859-2239-4b58-84af-94323066d666
https://research.vumc.nl/en/publications/baa42859-2239-4b58-84af-94323066d666
Autor:
M. Arfan Ikram, Antonia M. W. Coppus, Maaike Schuur, John C. van Swieten, Irina V. Zorkoltseva, Ben A. Oostra, Yurii S. Aulchenko, Tatiana I. Axenovich, Cornelia M van Duijn, Najaf Amin, Marcel M. Verbeek, Monique M.B. Breteler, Carla A. Ibrahim-Verbaas, Aaron Isaacs
Publikováno v:
Human Genetics, 131, 12, pp. 1869-76
Human Genetics, 131(12), 1869-1876. Springer-Verlag
Ibrahim-Verbaas, C A, Zorkoltseva, I V, Amin, N, Schuur, M, Coppus, A M W, Isaacs, A, Aulchenko, Y S, Breteler, M M B, Ikram, M A, Axenovich, T I, Verbeek, M M, van Swieten, J C, Oostra, B A & van Duijn, C M 2012, ' Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates A beta-40 levels to presenilin 2 ', Human Genetics, vol. 131, no. 12, pp. 1869-1876 . https://doi.org/10.1007/s00439-012-1210-2
Human Genetics, 131(12), 1869-76. Springer
Human Genetics, 131, 1869-76
Human Genetics, 131(12), 1869-1876. Springer Verlag
Human Genetics, 131(12), 1869-1876. Springer-Verlag
Ibrahim-Verbaas, C A, Zorkoltseva, I V, Amin, N, Schuur, M, Coppus, A M W, Isaacs, A, Aulchenko, Y S, Breteler, M M B, Ikram, M A, Axenovich, T I, Verbeek, M M, van Swieten, J C, Oostra, B A & van Duijn, C M 2012, ' Linkage analysis for plasma amyloid beta levels in persons with hypertension implicates A beta-40 levels to presenilin 2 ', Human Genetics, vol. 131, no. 12, pp. 1869-1876 . https://doi.org/10.1007/s00439-012-1210-2
Human Genetics, 131(12), 1869-76. Springer
Human Genetics, 131, 1869-76
Human Genetics, 131(12), 1869-1876. Springer Verlag
Item does not contain fulltext Plasma concentrations of Abeta40 and Abeta42 rise with age and are increased in people with mutations that cause early-onset Alzheimer's disease (AD). Amyloid beta (Abeta) plasma levels were successfully used as an (end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79708615f2493460264d67bcda405c0
https://hdl.handle.net/2066/108518
https://hdl.handle.net/2066/108518
Autor:
Toshiharu Suzuki, Takeshi Ikeuchi, Hiroyasu Akatsu, Tomoko Konno, Takayuki Yamamoto, Saori Hata, Yukiko Hamada, Tohru Yamamoto, Masahiro Maeda, Tadashi Nakaya, Yuhki Saito, Yuko Horikoshi-Sakuraba, Sam Gandy
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 6, Iss 1, p 76 (2011)
Molecular Neurodegeneration, Vol 6, Iss 1, p 76 (2011)
Background Aggregatable amyloid β-peptide (Aβ) and non-aggregatable p3-Alcα are metabolic products of the γ-secretase cleavage of amyloid β-protein precursor (APP) and Alcadeinα (Alcα), respectively. Familial AD (FAD) -linked mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05663c5dc56c5fa5c5f941e4c18302cc
https://pubmed.ncbi.nlm.nih.gov/22067061
https://pubmed.ncbi.nlm.nih.gov/22067061
Autor:
Peter Paul De Deyn, Judith J Leurs, Walter W Blomme, Nathalie Le Bastard, Sebastiaan Engelborghs
Publikováno v:
Journal of Alzheimer's disease
The objective of this study was to evaluate the diagnostic performance of full-length and N-truncated plasma amyloid-beta (Abeta) forms in patients with Alzheimer's disease (AD) and non-Alzheimer's disease dementia (non-AD) as compared to healthy con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab274a049b0d4116d7297e1a089d804a
https://hdl.handle.net/20.500.14017/78e6a17c-7ec0-4866-81cd-533391910b42
https://hdl.handle.net/20.500.14017/78e6a17c-7ec0-4866-81cd-533391910b42