Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Amy Yan"'
Autor:
Haixiang Yu, Shekhar Kumar, James W. Frederiksen, Vladimir N. Kolyadko, George Pitoc, Juliana Layzer, Amy Yan, Rachel Rempel, Samuel Francis, Sriram Krishnaswamy, Bruce A. Sullenger
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Potent and selective inhibition of the structurally homologous proteases of coagulation poses challenges for drug development. Hematophagous organisms frequently accomplish this by fashioning peptide inhibitors combining exosite and active s
Externí odkaz:
https://doaj.org/article/7a6f52c557ba4dfcb62c6ee0bf629bf7
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 781 (2024)
Traumatic brain injury is one of the leading causes of morbidity and mortality worldwide and is one of the major public healthcare burdens in the US, with millions of patients suffering from the traumatic brain injury itself (approximately 1.6 millio
Externí odkaz:
https://doaj.org/article/f09f940780a345e681b79ab11c1d7985
Autor:
Meiyan Jin, Cyna Shirazinejad, Bowen Wang, Amy Yan, Johannes Schöneberg, Srigokul Upadhyayula, Ke Xu, David G. Drubin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Drubin et al. use three different advanced imaging approaches to show that actin assembles preferentially at stalled clathrin-mediated endocytosis sites, where the actin pulls vesicles into the cell asymmetrically, as a bottle opener pulls off a cap.
Externí odkaz:
https://doaj.org/article/afc4fc14dac840cbb7a81fb75edc911f
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Aptamers could potentially be widely used in therapy and diagnostics. Here the authors use standardised assay conditions to compare aptamer properties in tumour targeting.
Externí odkaz:
https://doaj.org/article/35dae570879e42c5903ef88871d8aac0
Autor:
Samantha E Wilner, Brian Wengerter, Keith Maier, Maria de Lourdes Borba Magalhães, David Soriano Del Amo, Supriya Pai, Felipe Opazo, Silvio O Rizzoli, Amy Yan, Matthew Levy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
The transferrin receptor, CD71, is an attractive target for drug development because of its high expression on a number of cancer cell lines and the blood brain barrier. To generate serum-stabilized aptamers that recognize the human transferrin recep
Externí odkaz:
https://doaj.org/article/f49eee81e2054e35bc941fe8c69cbbd6
103
In the process of filing divorce, parents usually feel angry, depressed, and disappointed. As a result, it is difficult to reach a rational agreement. Therefore, family mediators not only have to empathize with the complicated emotions of bo
In the process of filing divorce, parents usually feel angry, depressed, and disappointed. As a result, it is difficult to reach a rational agreement. Therefore, family mediators not only have to empathize with the complicated emotions of bo
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/23865547917684638915
Autor:
Ronald CK Chan, Chun Kit Curtis To, Ka Chuen Tom Cheng, Tada Yoshikazu, Lai Ling Amy Yan, Gary M Tse
Publikováno v:
Histopathology. 82:198-210
This is a review on the use of artificial intelligence for digital breast pathology. A systematic search on PubMed was conducted, identifying 17,324 research papers related to breast cancer pathology. Following a semimanual screening, 664 papers were
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Aptamers represent a potentially important class of ligands for the development of diagnostics and therapeutics. However, it is often difficult to compare the function and specificity of many of these molecules as assay formats and conditions vary gr
Autor:
Stephanie Harris, Katherine Gerken, Stuart Clark‐Price, Ellan Hung, Tom Jukier, Amy Yanke, Kendon Kuo, Maureen McMichael
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 4, Pp 2165-2170 (2024)
Abstract Background Syndecan‐1 (SDC1) is an established marker of endothelial glycocalyx shedding. Most research on SDC1 has focused on plasma or serum concentrations, and little is known about urine concentrations. Objectives Measure urinary SDC1
Externí odkaz:
https://doaj.org/article/8e1f667623be4e8c8a691a9c8392a212
Autor:
Xirui Song, Haixiang Yu, Cynthia Sullenger, Bethany Powell Gray, Amy Yan, Linsley Kelly, Bruce Sullenger
Publikováno v:
Cancers; Volume 15; Issue 8; Pages: 2301
Strategies to direct drugs specifically to cancer cells have been increasingly explored, and significant progress has been made toward such targeted therapy. For example, drugs have been conjugated into tumor-targeting antibodies to enable delivery d