Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amy Y.M. Au"'
Autor:
Lily I. Huschtscha, Christine E. Napier, Jane R. Noble, Kylie Bower, Amy Y.M. Au, Hamish G. Campbell, Antony W. Braithwaite, Roger R. Reddel
Publikováno v:
BioTechniques, Vol 53, Iss 4, Pp 239-244 (2012)
Here we describe a method for growing fibroblasts from human skin explants that increases the number of cells obtained by up to two orders of magnitude, thus increasing the amount of material available for research and diagnostic purposes and potenti
Externí odkaz:
https://doaj.org/article/bc987da89fe24c3089e5110360f03c75
Autor:
Michael Fenech, Hilda A. Pickett, Nathan O'Callaghan, Dimphy Zeegers, Amy Y.M. Au, Grace Kah Mun Low, Graham Mayrhofer, M. Prakash Hande, Caroline Bull
Publikováno v:
Cancer prevention research (Philadelphia, Pa.). 7(1)
The essential role of dietary micronutrients for genome stability is well documented, yet the effect of folate deficiency or excess on telomeres is not known. Accordingly, human WIL2-NS cells were maintained in medium containing 30, 300, or 3,000 nmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936652b1418cd270ec5b60bb2f3434b8
https://pubmed.ncbi.nlm.nih.gov/24253316
https://pubmed.ncbi.nlm.nih.gov/24253316
Autor:
Christine E. Napier, Roger R. Reddel, Antony W. Braithwaite, Amy Y.M. Au, Jane R. Noble, Lily I. Huschtscha, Hamish Campbell, Kylie Bower
Publikováno v:
BioTechniques. 53(4)
Here we describe a method for growing fibroblasts from human skin explants that increases the number of cells obtained by up to two orders of magnitude, thus increasing the amount of material available for research and diagnostic purposes and potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400da771ad13dacb5b087ad67ffb56d4
https://pubmed.ncbi.nlm.nih.gov/23046507
https://pubmed.ncbi.nlm.nih.gov/23046507
Publikováno v:
Human molecular genetics. 20(23)
In human cancer cells with telomeres that have been over-lengthened by exogenous telomerase activity, telomere shortening can occur by a process that generates circles of double-stranded telomeric DNA (t-circles). Here, we demonstrate that this telom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298d0d8947c42c3fcd3d72e3a10f707d
https://pubmed.ncbi.nlm.nih.gov/21903669
https://pubmed.ncbi.nlm.nih.gov/21903669
Autor:
Harvey I. Pass, Scott B. Cohen, Torben Hackl, Roger R. Reddel, Amy Y.M. Au, Curtis C. Harris, Thomas Yeager
New treatments are needed for malignant pleural mesothelioma (MPM), which currently has a poor prognosis. Cellular immortalisation, one of the hallmarks of cancer, depends on the activity of a telomere length maintenance mechanism (TMM) – either te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579eb64f8a6afee656ab60a3a4551033
https://europepmc.org/articles/PMC3135747/
https://europepmc.org/articles/PMC3135747/
Autor:
Ian D. Cameron, Robert G. Cumming, Philip N. Sambrook, Jian Sheng Chen, Martyn Bullock, Roderick J. Clifton-Bligh, Lyn March, Tuan V. Nguyen, Amy Y.M. Au, Markus J. Seibel
Publikováno v:
Calcified Tissue International
CYP27B1 encodes mitochondrial 1α-hydroxylase, which converts 25-hydroxyvitamin D to its active 1,25-dihydroxylated metabolite. We tested the hypothesis that common variants in the CYP27B1 promoter are associated with fracture risk. The study was des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc43e6c457f8f61c60a8f78f9bd0cdb
https://pubmed.ncbi.nlm.nih.gov/21107545
https://pubmed.ncbi.nlm.nih.gov/21107545
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity
Autor:
Jeremy D. Henson, Roger R. Reddel, Andy C.-M. Chang, Lily I. Huschtscha, Ying Cao, Amy Y.M. Au, Hilda A. Pickett
Publikováno v:
Nature biotechnology. 27(12)
Alternative lengthening of telomeres (ALT) is likely to be an important target for anticancer treatment as approximately 10% of cancers depend on this telomere maintenance mechanism for continued growth, and inhibition of ALT can cause cellular senes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb203629abbfb5f937384e1549fa698
https://pubmed.ncbi.nlm.nih.gov/19935656
https://pubmed.ncbi.nlm.nih.gov/19935656
Autor:
Loretta Lau, Rebecca A. Dagg, Roger R. Reddel, Amy Y.M. Au, Janice A. Royds, Jeremy D. Henson
Publikováno v:
Nucleic Acids Research
Alternative lengthening of telomeres (ALT) is one of the two known telomere length maintenance mechanisms that are essential for the unlimited proliferation potential of cancer cells. Existing methods for detecting ALT in tumors require substantial a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c14e5375353a06944f4fd46b8ebd0f
http://europepmc.org/articles/PMC3553966
http://europepmc.org/articles/PMC3553966