Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Amy Y. Sato"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ab0bb140c69a4cf5a5719ab8212d7d56
Autor:
Silvia Marino, Nisreen Akel, Shenyang Li, Meloney Cregor, Meghan Jones, Betiana Perez, Gaston Troncoso, Jomeeka Meeks, Scott Stewart, Amy Y. Sato, Intawat Nookaew, Teresita Bellido
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract The mechanisms underlying the bone disease induced by diabetes are complex and not fully understood; and antiresorptive agents, the current standard of care, do not restore the weakened bone architecture. Herein, we reveal the diabetic bone
Externí odkaz:
https://doaj.org/article/f8602743f42c4095b8142500de95df68
Autor:
Andrew Clark, Subhadip Ghatak, Poornachander Reddy Guda, Mohamed S. El Masry, Yi Xuan, Amy Y. Sato, Teresita Bellido, Chandan K. Sen
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-6 (2022)
Abstract This work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNTMyoD) to injured tissue in vivo. TNTMyoD was performed on skin and successfully induced expression of myogenic factors. TNTMyoD was then used as a th
Externí odkaz:
https://doaj.org/article/cc5c879be10e4d89ac2ef9b7eda9acd4
Autor:
Silvia Marino, Nisreen Akel, Shenyang Li, Meloney Cregor, Meghan Jones, Betiana Perez, Gaston Troncoso, Jomeeka Meeks, Scott Stewart, Amy Y. Sato, Intawat Nookaew, Teresita Bellido
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/dd7db31cf66d42ffacd6152af9d737f6
Autor:
Whitney A. Bullock, April M. Hoggatt, Daniel J. Horan, Andrew J. Elmendorf, Amy Y. Sato, Teresita Bellido, Gabriela G. Loots, Fredrick M. Pavalko, Alexander G. Robling
Publikováno v:
iScience, Vol 20, Iss , Pp 205-215 (2019)
Summary: Wnt signaling plays a key role in regulating bone remodeling. In vitro studies suggest that sclerostin's inhibitory action on Lrp5 is facilitated by the membrane-associated receptor Lrp4. We generated an Lrp4 R1170W knockin mouse model (Lrp4
Externí odkaz:
https://doaj.org/article/f7f843d78c6348eabf7967aba03f1a68
Autor:
Teresita Bellido, Alexander G. Robling, April M. Hoggatt, Andrew J. Elmendorf, Daniel J. Horan, Amy Y. Sato, Fredrick M. Pavalko, Gabriela G. Loots, Whitney A. Bullock
Publikováno v:
iScience
iScience, Vol 20, Iss, Pp 205-215 (2019)
iScience, Vol 20, Iss, Pp 205-215 (2019)
Summary Wnt signaling plays a key role in regulating bone remodeling. In vitro studies suggest that sclerostin's inhibitory action on Lrp5 is facilitated by the membrane-associated receptor Lrp4. We generated an Lrp4 R1170W knockin mouse model (Lrp4K
Autor:
Kathleen M Hill Gallant, Maxime A Gallant, Drew M Brown, Amy Y Sato, Justin N Williams, David B Burr
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108262 (2014)
Fracture risk in type 2 diabetes is increased despite normal or high bone mineral density, implicating poor bone quality as a risk factor. Raloxifene improves bone material and mechanical properties independent of bone mineral density. This study aim
Externí odkaz:
https://doaj.org/article/c8369321fc08471798592af0e29e4f2b
Autor:
Roy B Choi, Cindy H. Nakatsu, Olivia Johnson, David B. Burr, George P. McCabe, Kevin McAndrews, Mary Ann Lila, Maria Maiz, Connie M. Weaver, Linda D McCabe, Mario G. Ferruzzi, Gretel G. Pellegrini, Amy Y. Sato, Meloney Cregor, Teresita Bellido, Munro Peacock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::426bb12ad101908fe5df8b2325462736
https://doi.org/10.1002/jbmr.4231/v2/response1
https://doi.org/10.1002/jbmr.4231/v2/response1
Autor:
James R. Tonra, Amy Y. Sato, Kevin McAndrews, Jesus Delgado-Calle, Carolina Sañudo, José A. Riancho, Benjamin Hancock, Angela Bruzzaniti, Teresita Bellido, Elive F. Likine
Publikováno v:
The FASEB Journal. 32:2878-2890
Parathyroid hormone (PTH) affects the skeleton by acting on osteocytes (Ots) in bone through yet unclear mechanisms. We report that matrix metalloproteinase 14 (MMP14) expression/activity are increased in bones from mice with genetic constitutive act
Glucocorticoid-Induced Bone Fragility Is Prevented in Female Mice by Blocking Pyk2/Anoikis Signaling
Autor:
Lilian I. Plotkin, Teresita Bellido, Kevin McAndrews, Amy Y. Sato, Troy Li, Keith W. Condon, Meloney Cregor
Publikováno v:
Endocrinology
Excess of glucocorticoids (GCs) is a leading cause of bone fragility, and therapeutic targets are sorely needed. We report that genetic deletion or pharmacological inhibition of proline-rich tyrosine kinase 2 (Pyk2) prevents GC-induced bone loss by o