Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amy Y, Tang"'
Autor:
Edward Geisinger, Nadav J. Mortman, Yunfei Dai, Murat Cokol, Sapna Syal, Andrew Farinha, Delaney G. Fisher, Amy Y. Tang, David W. Lazinski, Stephen Wood, Jon Anthony, Tim van Opijnen, Ralph R. Isberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
A unique cell envelope contributes to the antibiotic resistance of the pathogen Acinetobacter baumannii. Here, Geisinger et al. identify A. baumannii mutants with altered antibiotic susceptibility, infer the function of uncharacterized proteins invol
Externí odkaz:
https://doaj.org/article/c02ae759b9cd41e7bac28dc223d59326
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT The hospital-acquired pathogen Acinetobacter baumannii possesses a complex cell envelope that is key to its multidrug resistance and virulence. The bacterium, however, lacks many canonical enzymes that build the envelope in model organisms.
Externí odkaz:
https://doaj.org/article/15ca70e2b96d409386e7cd62fe4a791a
Autor:
Hayley I. Muendlein, Joseph Sarhan, Beiyun C. Liu, Wilson M. Connolly, Stephen A. Schworer, Irina Smirnova, Amy Y. Tang, Vladimir Ilyukha, Jodie Pietruska, Soroush Tahmasebi, Nahum Sonenberg, Alexei Degterev, Alexander Poltorak
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 699-713.e4 (2020)
Summary: Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activa
Externí odkaz:
https://doaj.org/article/b14db846e8cc4f8c8f65d98ff6c63481
Autor:
Shuvam Chaudhuri, Samuel Weinberg, Dongmei Wang, Lenore K. Yalom, Elena Montauti, Radhika Iyer, Amy Y. Tang, Manuel A. Torres Acosta, Jian Shen, Nikita Mani, Shengnan Wang, Kun Liu, Weiyuan Lu, Triet M. Bui, Laura D. Manzanares, Zeinab Dehghani, Ching Man Wai, Beixue Gao, Juncheng Wei, Yue Feng, Weiguo Cui, Benjamin D. Singer, Ronen Sumagin, Yana Zhang, Deyu Fang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6624a587bae4d0b0169ba97277b0e9f4
https://doi.org/10.2139/ssrn.4367303
https://doi.org/10.2139/ssrn.4367303
Autor:
Edward Geisinger, Nadav J. Mortman, Yunfei Dai, Murat Cokol, Sapna Syal, Andrew Farinha, Delaney G. Fisher, Amy Y. Tang, David W. Lazinski, Stephen Wood, Jon Anthony, Tim van Opijnen, Ralph R. Isberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20098-z
Externí odkaz:
https://doaj.org/article/fa2576b294a44e38ae7ded0298c1f51e
Autor:
Amy Y. Tang, Mei Zhou, Alexander N. Maillis, Kristina W. Lai, Peter A. Lane, Angela B. Snyder
Publikováno v:
Pediatric bloodcancerREFERENCES.
There have been significant changes in clinical guidelines for sickle cell disease (SCD) over the past two decades, including updated indications for hydroxyurea, transfusions, and iron overload management. In practice however, there are few studies
Autor:
Rowan O. Brothers, Katherine B. Turrentine, Mariam Akbar, Sydney Triplett, Tara M. Urner, Amy Y. Tang, Clark Brown, Erin M. Buckley
Publikováno v:
Blood. 140:8296-8297
Autor:
Vladimir Ilyukha, Alexei Degterev, Wilson M. Connolly, Hayley I. Muendlein, Beiyun C. Liu, Nahum Sonenberg, Jodie R. Pietruska, Alexander Poltorak, Stephen A Schworer, Amy Y. Tang, Irina Smirnova, Joseph Sarhan, Soroush Tahmasebi
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 699-713.e4 (2020)
Cell reports
Cell reports
SUMMARY Receptor-interacting protein kinase 1 (RIPK1) and 3 (RIPK3) are well known for their capacity to drive necroptosis via mixed-lineage kinase-like domain (MLKL). Recently, RIPK1/3 kinase activity has been shown to drive inflammation via activat
The hospital-acquired pathogen Acinetobacter baumannii possesses a complex cell envelope that is key to its multidrug resistance and virulence. The bacterium, however, lacks many canonical enzymes that build the envelope in model organisms. Instead,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39375a771db30c305159d60923f96e29
https://doi.org/10.1101/2021.09.22.461454
https://doi.org/10.1101/2021.09.22.461454
Autor:
Jinna Bai, Amy Y. Tang, Yunfei Dai, Andrew Farinha, Tim van Opijnen, Ralph R. Isberg, Germán Vargas-Cuebas, Edward Geisinger, Sapna Syal
Publikováno v:
J Bacteriol
Acinetobacter baumannii is a poorly understood bacterium capable of life-threatening infections in hospitals. Few antibiotics remain effective against this highly resistant pathogen. Development of rationally designed antimicrobials that can target A