Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Amy Y, Shih"'
Autor:
Aaron A. Thompson, Michael B. Harbut, Pei-Pei Kung, Nathan K. Karpowich, Jeffrey D. Branson, Joanna C. Grant, Deborah Hagan, Heather A. Pascual, Guoyun Bai, Reza Beheshti Zavareh, Heather R. Coate, Bernard C. Collins, Marjorie Côte, Christine F. Gelin, Kelly L. Damm-Ganamet, Hadi Gholami, Adam R. Huff, Luis Limon, Kevin J. Lumb, Puiying A. Mak, Kohki M. Nakafuku, Edmund V. Price, Amy Y. Shih, Mandana Tootoonchi, Nadeem A. Vellore, Jocelyn Wang, Na Wei, Jeannie Ziff, Scott B. Berger, James P. Edwards, Agnès Gardet, Siquan Sun, Jennifer E. Towne, Jennifer D. Venable, Zhicai Shi, Hariharan Venkatesan, Marie-Laure Rives, Sujata Sharma, Brock T. Shireman, Samantha J. Allen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
NKG2D (natural-killer group 2, member D) is a homodimeric transmembrane receptor that plays an important role in NK, γδ + , and CD8 + T cell-mediated immune responses to environmental stressors such as viral or bacterial infections and oxidative st
Autor:
Jacek Stalewski, Amy Y. Shih, Romeo Papazyan, Jocelyn Ramirez, Gerardo Ibanez, Peng Hsiao, Yong Yue, Jun Yin, Calen Badger, Shije Wu, Akemi Ueki, Bryan C. Fuchs, Marie-Laure Rives
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. :JPET-AR
Autor:
Renee L. DesJarlais, Tami Marrone, Jamie M. Schiffer, Amy Y. Shih, Taraneh Mirzadegan, Kelly L. Damm-Ganamet, Laura Pérez-Benito
Publikováno v:
Journal of Medicinal Chemistry. 63:1929-1936
The topic of gender equality within the United States workforce is receiving a great deal of attention. The field of chemistry is no exception and is increasingly focused on taking steps to achieve gender diversity within the chemistry workforce. Ove
Autor:
Robert A. Neff, Mack Flinspach, Alan Gibbs, Amy Y. Shih, Natali A. Minassian, Yi Liu, Ross Fellows, Ondrej Libiger, Stephanie Young, Michael W. Pennington, Michael J. Hunter, Alan D. Wickenden
Publikováno v:
Journal of Biological Chemistry. 295:1315-1327
Autor:
Amy Y. Shih, Ondrej Libiger, Stephanie Young, Alan Gibbs, Alan D. Wickenden, Michael J. Hunter, Ross Fellows, Yi Liu, Robert A. Neff, Michael W. Pennington, Natali A. Minassian, Mack Flinspach
Publikováno v:
Journal of Biological Chemistry. 295:1315-1327
Pain is a significant public health burden in the United States, and current treatment approaches rely heavily on opioids, which often have limited efficacy and can lead to addiction. In humans, functional loss of the voltage-gated sodium channel Nav
Publikováno v:
Journal of chemical information and modeling. 60(11)
Relative free energy perturbation (FEP) methods have become increasingly popular within the pharmaceutical industry; however, despite time constraints within drug discovery cycles, caution should be applied in the deployment of such methods as protei
Autor:
Kelly L, Damm-Ganamet, Renee L, DesJarlais, Tami, Marrone, Amy Y, Shih, Jamie M, Schiffer, Laura, Perez-Benito, Taraneh, Mirzadegan
Publikováno v:
Journal of medicinal chemistry. 63(5)
The topic of gender equality within the United States workforce is receiving a great deal of attention. The field of chemistry is no exception and is increasingly focused on taking steps to achieve gender diversity within the chemistry workforce. Ove
Autor:
Robert A, Neff, Mack, Flinspach, Alan, Gibbs, Amy Y, Shih, Natali A, Minassian, Yi, Liu, Ross, Fellows, Ondrej, Libiger, Stephanie, Young, Michael W, Pennington, Michael J, Hunter, Alan D, Wickenden
Publikováno v:
J Biol Chem
Pain is a significant public health burden in the United States, and current treatment approaches rely heavily on opioids, which often have limited efficacy and can lead to addiction. In humans, functional loss of the voltage-gated sodium channel Na(
Publikováno v:
Biophysical Journal. 114:32-39
The stimulator-of-interferon-genes (STING) protein is involved in innate immunity. It has recently been shown that modulation of STING can lead to an aggressive antitumor response. DMXAA is an antitumor agent that had shown great promise in murine mo
Autor:
Lien Wang, Jiejun Wu, Amy Y. Shih, Chester Kuei, Pascal Bonaventure, Timothy W. Lovenberg, Diane Nepomuceno, Michelle Wennerholm, Grace Lee, Changlu Liu, Frances Fan
Publikováno v:
Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 7, Iss 1, Pp n/a-n/a (2019)
Pharmacology Research & Perspectives, Vol 7, Iss 1, Pp n/a-n/a (2019)
GPR139 is a Gq‐coupled receptor activated by the essential amino acids L‐tryptophan (L‐Trp) and L‐phenylalanine (L‐Phe). We carried out mutagenesis studies of the human GPR139 receptor to identify the critical structural motifs required for