Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Amy W Lasek"'
Autor:
Daniel Rafferty, Luana Martins de Carvalho, Mason Sutter, Katlyn Heneghan, Victoria Nelson, Megan Leitner, Charlotte Bolch, Amy W Lasek, Prasanth Puthanveetil
Publikováno v:
Redox Experimental Medicine, Vol 2023, Iss 1, Pp 1-16 (2023)
Binge drinking is a growing health concern among all age groups. The ability of individuals to handle ethanol in their systems differs not due to differences in enzyme expression but also due to other factors. Vital organs including brain, liver, hea
Externí odkaz:
https://doaj.org/article/51bb9b4c9cba44568f712762fce9cc61
Autor:
Cassandre Coles, Amy W Lasek
Publikováno v:
Neuroscience Insights, Vol 16 (2021)
Alcohol use disorder is associated with pathophysiological changes in the dopaminergic system. Orthodenticle homeobox 2 (OTX2) is a transcription factor important for the development of dopaminergic neurons residing in the ventral tegmental area (VTA
Externí odkaz:
https://doaj.org/article/f9219f592092400da7bcba544ad57013
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187698 (2017)
Gender differences in psychiatric disorders such as addiction may be modulated by the steroid hormone estrogen. For instance, 17β-estradiol (E2), the predominant form of circulating estrogen in pre-menopausal females, increases ethanol consumption,
Externí odkaz:
https://doaj.org/article/4d356314f72c4085a36e394b0cd1e57f
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34559 (2012)
Pavlovian fear conditioning is an associative learning paradigm in which mice learn to associate a neutral conditioned stimulus with an aversive unconditioned stimulus. In this study, we demonstrate a novel role for the transcriptional regulator Lmo4
Externí odkaz:
https://doaj.org/article/ed4a7bd5666b4b5bbcc7975037716210
Autor:
Amy W Lasek, Jana Lim, Christopher L Kliethermes, Karen H Berger, Geoff Joslyn, Gerry Brush, Liquan Xue, Margaret Robertson, Monica S Moore, Karen Vranizan, Stephan W Morris, Marc A Schuckit, Raymond L White, Ulrike Heberlein
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22636 (2011)
Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in various human cancers. We have determined that Alk is associated with altered behavioral r
Externí odkaz:
https://doaj.org/article/a85a1905315e4389912e69a18a2d5452
Autor:
Hu Chen, Yunlong Lu, Rui Xiong, Carlo I. Rosales, Cassandre Coles, Kana Hamada, Nuria Asad, Gregory R. J. Thatcher, Amy W. Lasek
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:1313-1320
Greater circulating levels of the steroid hormone 17β-estradiol (E2) are associated with higher levels of binge drinking in women. In female mice, estrogen receptors in the ventral tegmental area, a dopaminergic region of the brain involved in the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162ecd33000b600985ebe3abd2cf9c24
https://doi.org/10.1111/acer.14874
https://doi.org/10.1111/acer.14874
Publikováno v:
Frontiers in Psychiatry. 14
Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new therapeutic targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f46626862ae96b57541538a09f77d3d5
https://doi.org/10.3389/fpsyt.2023.1122423
https://doi.org/10.3389/fpsyt.2023.1122423
Publikováno v:
bioRxiv
Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological factors that underly compulsive drinking will allow for the development of new therapeutic targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01b62b7b9fe698d843a414b12d8ec29
https://doi.org/10.1101/2023.01.27.525899
https://doi.org/10.1101/2023.01.27.525899
Autor:
Milagros Galán-Llario, María Rodríguez-Zapata, Teresa Fontán-Baselga, Esther Gramage, Marta Vicente-Rodríguez, José María Zapico, Beatriz de Pascual-Teresa, Amy W. Lasek, Gonzalo Herradón
En: Neuropharmacology ISSN. 0028-3908 n. 227 (2023) Pleiotrophin (PTN) is a cytokine that modulates ethanol drinking and reward and regulates glial responses in different contexts. PTN is an inhibitor of Receptor Protein Tyrosine Phosphatase (RPTP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6215d53e6dee0abc2649d756da085b6
http://hdl.handle.net/10637/14115
http://hdl.handle.net/10637/14115
Publikováno v:
Alcohol. 109:78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7a438a5d932b950b86039fe95a28ea3
https://doi.org/10.1016/j.alcohol.2023.03.050
https://doi.org/10.1016/j.alcohol.2023.03.050