Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Amy W, Chung"'
Autor:
Isobel S. Walker, Saber Dini, Elizabeth H. Aitken, Timon Damelang, Wina Hasang, Agersew Alemu, Anja T. R. Jensen, Janavi S. Rambhatla, D. Herbert Opi, Michael F. Duffy, Eizo Takashima, Visopo Harawa, Takafumi Tsuboi, Julie A. Simpson, Wilson Mandala, Terrie E. Taylor, Karl B. Seydel, Amy W. Chung, Stephen J. Rogerson
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins are expressed on the surface of infected erythrocytes, mediating parasite sequestration in the vasculature. PfEMP1 is a major target of protective antibodies,
Externí odkaz:
https://doaj.org/article/207469fd56754378a72987ad51f59013
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal
Externí odkaz:
https://doaj.org/article/c15b260c86f84dffa03009a6bb0b59de
Autor:
Natalie Lorenz, Reuben McGregor, Alana L. Whitcombe, Prachi Sharma, Ciara Ramiah, Francis Middleton, Michael G. Baker, William J. Martin, Nigel J. Wilson, Amy W. Chung, Nicole J. Moreland
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110558- (2024)
Summary: Understanding the immune profile of acute rheumatic fever (ARF), a serious post-infectious sequelae of Streptococcal pyogenes (group A Streptococcus [GAS]), could inform disease pathogenesis and management. Circulating cytokines, immunoglobu
Externí odkaz:
https://doaj.org/article/b13c75f917df48d4a74aa75b9fe44bec
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/dbcc812df33143d0a5c9724faf5629b8
Autor:
Ruth A Purcell, L Carissa Aurelia, Robyn Esterbauer, Lilith F Allen, Katherine A Bond, Deborah A Williamson, Janine M Trevillyan, Jason A Trubiano, Jennifer J Juno, Adam K Wheatley, Miles P Davenport, Thi HO Nguyen, Katherine Kedzierska, Stephen J Kent, Kevin John Selva, Amy W Chung
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives Amino acid variations across more than 30 immunoglobulin (Ig) allotypes may introduce structural changes that influence recognition by anti‐Ig detection reagents, consequently confounding interpretation of antibody responses, pa
Externí odkaz:
https://doaj.org/article/36429c3f56ec4184a7eb909944245504
Autor:
Terry M. Nolan, Georgia Deliyannis, Maryanne Griffith, Sabine Braat, Lilith F. Allen, Jennifer Audsley, Amy W. Chung, Marcin Ciula, Nicholas A. Gherardin, Michelle L. Giles, Tom P. Gordon, Samantha L. Grimley, Lana Horng, David C. Jackson, Jennifer A. Juno, Katherine Kedzierska, Stephen J. Kent, Sharon R. Lewin, Mason Littlejohn, Hayley A. McQuilten, Francesca L. Mordant, Thi H.O. Nguyen, Vanessa Pac Soo, Briony Price, Damian F.J. Purcell, Pradhipa Ramanathan, Samuel J. Redmond, Steven Rockman, Zheng Ruan, Joseph Sasadeusz, Julie A. Simpson, Kanta Subbarao, Stewart A. Fabb, Thomas J. Payne, Asuka Takanashi, Chee Wah Tan, Joseph Torresi, Jing Jing Wang, Lin-Fa Wang, Hareth Al-Wassiti, Chinn Yi Wong, Sophie Zaloumis, Colin W. Pouton, Dale I. Godfrey
Publikováno v:
EBioMedicine, Vol 98, Iss , Pp 104878- (2023)
Summary: Background: SARS-CoV-2 booster vaccination should ideally enhance protection against variants and minimise immune imprinting. This Phase I trial evaluated two vaccines targeting SARS-CoV-2 beta-variant receptor-binding domain (RBD): a recomb
Externí odkaz:
https://doaj.org/article/759603e2b16e4eff9551a0f453f831d4
Autor:
Kevin J. Selva, Pradhipa Ramanathan, Ebene R. Haycroft, Arnold Reynaldi, Deborah Cromer, Chee Wah Tan, Lin-Fa Wang, Bruce D. Wines, P. Mark Hogarth, Laura E. Downie, Samantha K. Davis, Ruth A. Purcell, Helen E. Kent, Jennifer A. Juno, Adam K. Wheatley, Miles P. Davenport, Stephen J. Kent, Amy W. Chung
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination is crucial to develop strategies for longer term immunity, especially against emerging viral variants. We profiled serial paired mucosal and plasma antibodies from
Externí odkaz:
https://doaj.org/article/5642c4f059134a179ab08b3553b928dd
Autor:
Meseret W. Kassa, Wina Hasang, André Barateiro, Timon Damelang, Jessica Brewster, Jamille G. Dombrowski, Rhea J. Longley, Amy W. Chung, Gerhard Wunderlich, Ivo Mueller, Elizabeth H. Aitken, Claudio R. F. Marinho, Stephen J. Rogerson
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Pregnant women have increased susceptibility to Plasmodium falciparum malaria and acquire protective antibodies over successive pregnancies. Most studies that investigated malaria antibody responses in pregnant women are from high
Externí odkaz:
https://doaj.org/article/145769ab7c974e88849fdad194847212
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Vaccine efficacy determined within the controlled environment of a clinical trial is usually substantially greater than real-world vaccine effectiveness. Typically, this results from reduced protection of immunologically vulnerable populations, such
Externí odkaz:
https://doaj.org/article/f556985c888d4a67bca02ba11d92ea3c
Autor:
Georgia Deliyannis, Nicholas A. Gherardin, Chinn Yi Wong, Samantha L. Grimley, James P. Cooney, Samuel J. Redmond, Paula Ellenberg, Kathryn C. Davidson, Francesca L. Mordant, Tim Smith, Marianne Gillard, Ester Lopez, Julie McAuley, Chee Wah Tan, Jing J. Wang, Weiguang Zeng, Mason Littlejohn, Runhong Zhou, Jasper Fuk-Woo Chan, Zhi-wei Chen, Airn E. Hartwig, Richard Bowen, Jason M. Mackenzie, Elizabeth Vincan, Joseph Torresi, Katherine Kedzierska, Colin W. Pouton, Tom P. Gordon, Lin-fa Wang, Stephen J. Kent, Adam K. Wheatley, Sharon R. Lewin, Kanta Subbarao, Amy W. Chung, Marc Pellegrini, Trent Munro, Terry Nolan, Steven Rockman, David C. Jackson, Damian F.J. Purcell, Dale I. Godfrey
Publikováno v:
EBioMedicine, Vol 92, Iss , Pp 104574- (2023)
Summary: Background: The SARS-CoV-2 global pandemic has fuelled the generation of vaccines at an unprecedented pace and scale. However, many challenges remain, including: the emergence of vaccine-resistant mutant viruses, vaccine stability during sto
Externí odkaz:
https://doaj.org/article/3f8a77f37e1f498db21c0e05005ef2d3