Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amy V. Poole"'
Autor:
James Meehan, Mark Gray, Carlos Martínez-Pérez, Charlene Kay, Lisa Y. Pang, Jennifer A. Fraser, Amy V. Poole, Ian H. Kunkler, Simon P. Langdon, David Argyle, Arran K. Turnbull
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Radiotherapy remains an important treatment modality in nearly two thirds of all cancers, including the primary curative or palliative treatment of breast cancer. Unfortunately, largely due to tumor heterogeneity, tumor radiotherapy response rates ca
Externí odkaz:
https://doaj.org/article/f1ccff91ed624c99bba0f0182c1ae428
Publikováno v:
Fraser, J A, Sutton, J E, Tazayoni, S, Bruce, I & Poole, A V 2019, ' hASH1 nuclear localization persists in neuroendocrine transdifferentiated prostate cancer cells, even upon reintroduction of androgen ', Scientific Reports, vol. 9, no. 1, 19076 . https://doi.org/10.1038/s41598-019-55665-y
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Neuroendocrine prostate cancer (NEPC) is thought to arise as prostate adenocarcinoma cells transdifferentiate into neuroendocrine (NE) cells to escape potent anti-androgen therapies however, the exact molecular events accompanying NE transdifferentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a040feb2a4a5e5511c1679b29f4364
https://hdl.handle.net/20.500.11820/01af5205-5635-4103-9cac-b3293438248b
https://hdl.handle.net/20.500.11820/01af5205-5635-4103-9cac-b3293438248b
Publikováno v:
Journal of Neurochemistry. 140:195-209
Stroke is one of the major causes of death and disability worldwide. The major type of stroke is an ischaemic one, which is caused by a blockage that interrupts blood flow to the brain. There are currently very few pharmacological strategies to reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143e3e7cc3dd3663829d9e2bceb198a2
https://doi.org/10.1111/jnc.13901
https://doi.org/10.1111/jnc.13901
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185664 (2017)
PLoS ONE
Baudel, M A S M-A, Rae, M T, Darlison, M G, Poole, A & Fraser, J 2017, ' Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia ', PLoS ONE, vol. 12, no. 10, e0185664 . https://doi.org/10.1371/journal.pone.0185664
PLoS ONE
Baudel, M A S M-A, Rae, M T, Darlison, M G, Poole, A & Fraser, J 2017, ' Preferential activation of HIF-2α adaptive signalling in neuronal-like cells in response to acute hypoxia ', PLoS ONE, vol. 12, no. 10, e0185664 . https://doi.org/10.1371/journal.pone.0185664
Stroke causes severe neuronal damage as disrupted cerebral blood flow starves neurons of oxygen and glucose. The hypoxia inducible factors (HIF-1α and HIF-2α) orchestrate oxygen homeostasis and regulate specific aspects of hypoxic adaptation. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc44a01f375b36e9429a1e8fd2d24c2e
http://europepmc.org/articles/PMC5624621?pdf=render
http://europepmc.org/articles/PMC5624621?pdf=render
Autor:
Irene L. Llorente, Sheyla Montori, S. Dos_Anjos, Beatriz Martínez-Villayandre, Marta Regueiro-Purriños, Arsenio Fernández-López, Amy V. Poole, Mark G. Darlison
Publikováno v:
Neuropathology and Applied Neurobiology. 38:710-722
S. Montori, S. Dos_Anjos, A. Poole, M. M. Regueiro-Purrinos, I. L. Llorente, M. G. Darlison, A. Fernandez-Lopez and B. Martinez-Villayandre (2012) Neuropathology and Applied Neurobiology38, 710–722 Differential effect of transient global ischaemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fe47306dcdadcb2dff788308a908dc5
https://doi.org/10.1111/j.1365-2990.2012.01254.x
https://doi.org/10.1111/j.1365-2990.2012.01254.x
Autor:
Amy V. Poole, Beatriz Martínez-Villayandre, Mark G. Darlison, Diego Pérez-Rodríguez, Arsenio Fernández-López, Severiano Dos-Anjos, Irene L. Llorente
Publikováno v:
Brain research. 1533
Assays on "ex vivo" sections of rat hippocampus and rat cerebral cortex, subjected to oxygen and glucose deprivation (OGD) and a three-hour reperfusion-like (RL) recovery, were performed in the presence of either GABA or the GABA(A) receptor binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0c266186e38c78a66016c05a893737
https://pubmed.ncbi.nlm.nih.gov/23969196
https://pubmed.ncbi.nlm.nih.gov/23969196