Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Amy Turnbull"'
Autor:
Dean Stamos, Michael Liu, Beth Fleck, Lance Goulet, Weichao Chen, Harmon J. Zuccola, Phillip W. Snyder, Dao Tran, Peggy Chiang, James Reynolds, Azin Nezami, Samuel Sperry, Khisal Ahmed Alvi, Alcacio Timothy, Lisa Woody, William Kargo, Amy Turnbull, Timothy Neubert, Justin T. Ernst
Publikováno v:
Journal of Medicinal Chemistry. 57:3382-3400
A structure-based drug design strategy was used to optimize a novel benzolactam series of HSP90α/β inhibitors to achieve >1000-fold selectivity versus the HSP90 endoplasmic reticulum and mitochondrial isoforms (GRP94 and TRAP1, respectively). Selec
Autor:
Harmon J. Zuccola, Bryan W. Vought, Michael Liu, Justin T. Ernst, E. Adam Kallel, Timothy Neubert, Amy Turnbull, Kevin Beaumont, Dean Stamos
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:204-208
HSP90 continues to be a target of interest for neurodegeneration indications. Selective knockdown of the HSP90 cytosolic isoforms α and β is sufficient to reduce mutant huntingtin protein levels in vitro. Chemotype-dependent binding conformations o
Autor:
Khare, Amy Turnbull
In the early 2000s, Chicago emerged as an archetypal city in the broader movement to remake public housing. Chicago’s Plan for Transformation committed upwards of $1.5 billion to demolish high-rise buildings, rehabilitate a portion of existing stoc
Externí odkaz:
http://pqdtopen.proquest.com/#viewpdf?dispub=10129558
Autor:
G. J. Buzz Bronicki, Amy Turnbull
Publikováno v:
Journal of the Association for Persons with Severe Handicaps. 12:216-217
This study is a follow-up of my 1985 school science project (Turnbull & Bronicki, 1986) that I did in the fourth grade. In my 1985 study, I gave an attitude test to kids in two second grade classrooms. Then I taught a 50-min lesson about mental retar