Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Amy Stieler Stewart"'
Autor:
Amy Stieler Stewart, Jamie J. Kopper, Caroline McKinney-Aguirre, Brittany Veerasamy, Dipak Kumar Sahoo, John M. Freund, Liara M. Gonzalez
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
Gastrointestinal disease is a leading cause of death in mature horses. A lack of in vitro modeling has impeded the development of novel therapeutics. The objectives of this study were to develop and further characterize a small intestinal monolayer c
Externí odkaz:
https://doaj.org/article/1d71bfe0aae84ba38b708dc3ed7a17a1
Autor:
Amy Stieler Stewart, Cecilia R. Schaaf, Brittany Veerasammy, John M. Freund, Liara M. Gonzalez
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-7 (2022)
Abstract Background Equine intestinal epithelial stem cells (ISCs) serve as potential targets to treat horses with severe intestinal injury. The ability to isolate and store ISCs from intestinal biopsies creates an opportunity for both in vitro exper
Externí odkaz:
https://doaj.org/article/8ea0f5e5299348519bbe003976e43959
Publikováno v:
Equine Ophthalmology. :721-791
Autor:
James B Robertson, Amy Stieler Stewart, Jennifer Luff, Cecilia Schaaf, Thomas C. Becker, Liara M. Gonzalez, Sara R Tufts, John M. Freund
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 321:G588-G602
This paper supports that rISCs are resistant to ischemic injury and likely an important source of cellular renewal following near-complete epithelial loss. Furthermore, we have evidence that HOPX controls ISC activity state and may be a critical sign
Autor:
Amy Stieler, Stewart, Cecilia Renee, Schaaf, Jennifer A, Luff, John M, Freund, Thomas C, Becker, Sara R, Tufts, James B, Robertson, Liara M, Gonzalez
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Intestinal ischemia is a life-threatening emergency with mortality rates of 50%–80% due to epithelial cell death and resultant barrier loss. Loss of the epithelial barrier occurs in conditions including intestinal volvulus and neonatal necrotizing
Autor:
Ludwig E, Andrew S. Barbas, Debra L. Sudan, Amy Stieler Stewart, Garman K, John M. Freund, Nader Abraham, Cecilia Schaaf, Liara M. Gonzalez, Veerasammy B
Publikováno v:
Transplantation. 105:S51-S51
Autor:
Nader Abraham, Garman K, Amy Stieler Stewart, John M. Freund, Debra L. Sudan, Kucera C, Ludwig E, Andrew S. Barbas, Liara M. Gonzalez, Veerasammy B
Publikováno v:
Transplantation. 105:S43-S43
Publikováno v:
Journal of Equine Veterinary Science. 52:10-22
All species, including horses, suffer from alterations that increase intestinal permeability. These alterations, also known as "leaky gut," may lead to severe disease as the normal intestinal barrier becomes compromised and can no longer protect agai
Autor:
John M. Freund, Christopher M. Dekaney, Amy Stieler Stewart, Scott T. Magness, Cecilia Renee Kucera, Liara M. Gonzalez, Anthony T. Blikslager
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 316(4)
Intestinal ischemia is an abdominal emergency with a mortality rate >50%, leading to epithelial barrier loss and subsequent sepsis. Epithelial renewal and repair after injury depend on intestinal epithelial stem cells (ISC) that reside within the cry
Intestinal Stem Cell Isolation and Culture in a Porcine Model of Segmental Small Intestinal Ischemia
Publikováno v:
Journal of Visualized Experiments : JoVE
Intestinal ischemia remains a major cause of morbidity and mortality in human and veterinary patients. Many disease processes result in intestinal ischemia, when the blood supply and therefore oxygen is decreased to the intestine. This leads to intes