TorsinA controls TAN line assembly and the retrograde flow of dorsal perinuclear actin cables during rearward nuclear movement

Autor: Amy Schoenhofen, Alex J. McQuown, G. W. Gant Luxton, Nathan J. Harris, Howard J. Worman, Brian M. Woolums, Gregg G. Gundersen, Patrick T. Willey, Cosmo A. Saunders, William T. Dauer, Yuexia Wang

Publikováno v: The Journal of Cell Biology

In fibroblasts and myoblasts polarizing for migration, retrograde actin flow moves the nucleus rearward, orienting the centrosome toward the leading edge. The nucleus engages moving dorsal actin cables through linear arrays of nesprin-2G and SUN2 cal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b05a07b92e231581e8ce34b4eceb05b
https://doi.org/10.1083/jcb.201507113

Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning

Autor: Nathan J. Harris, Amy Schoenhofen, Baila Elkin, Natalie E. Cain, Brian M. Woolums, Hongyan Hao, Daniel A. Starr, Zeinab Jahed, Venecia A. Valdez, Leslie A Herrera, G. W. Gant Luxton, Mohammad R. K. Mofrad

Publikováno v: Current biology : CB, vol 28, iss 19
Cain, NE; Jahed, Z; Schoenhofen, A; Valdez, VA; Elkin, B; Hao, H; et al.(2018). Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning. Current Biology, 28(19), 3086-3097.e4. doi: 10.1016/j.cub.2018.08.001. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/4d50b0dp

© 2018 Elsevier Ltd Many nuclear positioning events involve linker of nucleoskeleton and cytoskeleton (LINC) complexes, which transmit forces generated by the cytoskeleton across the nuclear envelope. LINC complexes are formed by trans-luminal inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac5f06c3643f1d6af5dc450ed2b99e2
https://doi.org/10.1016/j.cub.2018.08.001