Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amy Sawtell"'
Autor:
Zhi Li, Tom Hodgkinson, Elizabeth J. Gothard, Soulmaz Boroumand, Rebecca Lamb, Ian Cummins, Priyanka Narang, Amy Sawtell, Jenny Coles, German Leonov, Andrea Reboldi, Christopher D. Buckley, Tom Cupedo, Christian Siebel, Ardeshir Bayat, Mark C. Coles, Carrie A. Ambler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
In normal skin, Notch directs keratinocytes to terminally differentiate. Here the authors show that Notch1 has a wider role in skin repair; Notch1 is activated in keratinocytes after damage and drives transcription of TNFα and inflammatory chemokine
Externí odkaz:
https://doaj.org/article/843bd1d443c040959d4e14ce28f79819
Autor:
Daniel Moyo, Lynette Beattie, Paul S. Andrews, John W. J. Moore, Jon Timmis, Amy Sawtell, Stefan Hoehme, Adam T. Sampson, Paul M. Kaye
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cellular activation in trans by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated
Externí odkaz:
https://doaj.org/article/10892fa7b57246f2b60b06f207672862
Autor:
Stefano Caserta, Norman Nausch, Amy Sawtell, Rebecca Drummond, Tom Barr, Andrew S Macdonald, Francisca Mutapi, Rose Zamoyska
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35466 (2012)
Certain parasites have evolved to evade the immune response and establish chronic infections that may persist for many years. T cell responses in these conditions become muted despite ongoing infection. Upregulation of surface receptors with inhibito
Externí odkaz:
https://doaj.org/article/345b9478c1014c4db3d8a4eb99488617
Autor:
Roger Leigh, Mark Coles, Jason Cosgrove, James Butler, Simon Jarrett, Jon Timmis, Amy Sawtell
Publikováno v:
Biophysics of Infection ISBN: 9783319321875
Immune responses occur as a result of stochastic interactions between a plethora of different cell types and molecules that regulate the migration and function of innate and adaptive immune cells to drive protection from pathogen infection. The traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba0e887608ef9c522d9b66e828563419
https://doi.org/10.1007/978-3-319-32189-9_20
https://doi.org/10.1007/978-3-319-32189-9_20
Autor:
Myriam Chimen, Simon Jones, Lynne R. Prince, Sarah R. Walmsley, Geoffrey Holmes, Sean R. Anderson, Stuart N. Farrow, Amy Sawtell, Roberto Solari, Mark Coles, Daniel Irimia, Stephen A. Renshaw, Visakan Kadirkamanathan, Aleksandra Bojarczuk, Anne L. Robertson, Bashar Hamza, Joseph A Willson, Catherine A. Loynes, Moira K. B. Whyte, Joseph Burgon, G. Ed Rainger
Diseases of failed inflammation resolution are common and largely incurable. Therapeutic induction of inflammation resolution is an attractive strategy to bring about healing without increasing susceptibility to infection. However, therapeutic target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a10e9f5a7e2acc25dadbdee4252cf8
https://eprints.whiterose.ac.uk/110823/1/nihms644781.pdf
https://eprints.whiterose.ac.uk/110823/1/nihms644781.pdf
Autor:
Rose Zamoyska, Tom A. Barr, Rebecca A. Drummond, Andrew S. MacDonald, Stefano Caserta, Francisca Mutapi, Amy Sawtell, Norman Nausch
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e35466 (2012)
Caserta, S, Nausch, N, Sawtell, A, Drummond, R, Barr, T, Macdonald, A S, Mutapi, F & Zamoyska, R 2012, ' Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells ', PLoS ONE, vol. 7, no. 4, e35466 . https://doi.org/10.1371/journal.pone.0035466
PLoS ONE, Vol 7, Iss 4, p e35466 (2012)
Caserta, S, Nausch, N, Sawtell, A, Drummond, R, Barr, T, Macdonald, A S, Mutapi, F & Zamoyska, R 2012, ' Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells ', PLoS ONE, vol. 7, no. 4, e35466 . https://doi.org/10.1371/journal.pone.0035466
Certain parasites have evolved to evade the immune response and establish chronic infections that may persist for many years. T cell responses in these conditions become muted despite ongoing infection. Upregulation of surface receptors with inhibito