Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Amy S. Ruppert"'
Autor:
Pallawi Torka, Levi D. Pederson, Michael V. Knopp, David Poon, Jun Zhang, Brad S. Kahl, Howard R. Higley, Gary Kelloff, Jonathan W. Friedberg, Lawrence H. Schwartz, Wyndham H. Wilson, John P. Leonard, Nancy L. Bartlett, Heiko Schöder, Amy S. Ruppert
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8211-8217 (2023)
Abstract Background Quantitative methods of Fluorodeoxyglucose Positron Emission Tomography (FDG‐PET) interpretation, including the percent change in FDG uptake from baseline (ΔSUV), are under investigation in lymphoma to overcome challenges assoc
Externí odkaz:
https://doaj.org/article/6687e78018644574b3cb698938d52e76
Autor:
Nicole Lamanna, Constantine Tam, Wojciech Jurczak, Arrin Kontos, Heiko Konig, Amy S. Ruppert, Donald E. Tsai
Publikováno v:
HemaSphere, Vol 7, p e724362f (2023)
Externí odkaz:
https://doaj.org/article/7daeae8fea894c9aad08af3f4ae743d7
Autor:
Lydia Scarfò, Manish R. Patel, Toby A. Eyre, Wojciech Jurczak, David Lewis, Thomas Gastinne, Shuo MA, Jonathon B. Cohen, Krish Patel, Jennifer R. Brown, Talha Munir, Ewa Lech-Maranda, Marc S. Hoffmann, Chaitra S. Ujjani, Bita Fakhri, Michael Wang, Koji Izutsu, Hirokazu Nagai, Constantine S. Tam, John F. Seymour, Joanna Rhodes, Julie Vose, Matthew Mckinney, James N. Gerson, Minal A. Barve, Bryone Kuss, Youngil Koh, Wei Gao, Amy S. Ruppert, Richard A. Walgren, Donald E. Tsai, Binoj Nair, Katherine Bao, Anthony R. Mato, Chan Y. Cheah, M Lia Palomba
Publikováno v:
HemaSphere, Vol 7, p e852670f (2023)
Externí odkaz:
https://doaj.org/article/a040220921ef4307b9e157dc91a3150b
Autor:
Janek S. Walker, Zachary A. Hing, Steven Sher, James Cronin, Katie Williams, Bonnie Harrington, Jordan N. Skinner, Casey B. Cempre, Charles T. Gregory, Alexander Pan, Max Yano, Larry P. Beaver, Brandi R. Walker, Jadwiga M. Labanowska, Nyla A. Heerema, Krzysztof Mrózek, Jennifer A. Woyach, Amy S. Ruppert, Amy Lehman, Hatice Gulcin Ozer, Vincenzo Coppola, Pearlly Yan, John C. Byrd, James S. Blachly, Rosa Lapalombella
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Some genes that are part of balanced translocations are reported as drivers for tumourigenesis. Here, the authors report a translocation involving MTCP1 in chronic lymphocytic leukemia and show that MTCP1 overexpression leads to the disease in a muri
Externí odkaz:
https://doaj.org/article/810bfd0089064a989b380ab83b7f18b0
Autor:
Amy S. Ruppert, Abigail B. Shoben
Publikováno v:
Contemporary Clinical Trials Communications, Vol 12, Iss , Pp 40-50 (2018)
To evaluate the overall success rate of a new drug, phase 1, 2, and 3 trials were simulated using eight toxicity and two non-decreasing efficacy profiles. Six phase 1 designs including the standard 3 + 3, CCD, BOIN, mTPI, mTPI-2, and CRM were conside
Externí odkaz:
https://doaj.org/article/686aa3db8077406b95d80198d509449d
Autor:
Nyla A. Heerema, Natarajan Muthusamy, Qiuhong Zhao, Amy S. Ruppert, Heather Breidenbach, Leslie A. Andritsos, Michael R. Grever, Kami J. Maddocks, Jennifer Woyach, Farrukh Awan, Meixiao Long, Amber Gordon, Caitlin Coombes, John C. Byrd
Publikováno v:
Haematologica, Vol 106, Iss 6 (2020)
Mutations of the IGH variable region in patients with chronic lymphocytic leukemia (CLL) are associated with a favorable prognosis. Cytogenetic complexity (>3 unrelated aberrations) and translocations have been associated with an unfavorable prognosi
Externí odkaz:
https://doaj.org/article/c1f8c37f9c954bf6a8dafb620cb0ea2a
Autor:
Deborah M. Stephens, Amy S. Ruppert, Kristie Blum, Jeffrey Jones, Joseph M. Flynn, Amy J. Johnson, Jia Ji, Mitch A. Phelps, Michael R. Grever, John C. Byrd
Publikováno v:
Haematologica, Vol 97, Iss 3 (2012)
Older chronic lymphocytic leukemia patients have poor outcomes with standard treatments and are underrepresented in clinical trials. We retrospectively reviewed outcomes of refractory chronic lymphocytic leukemia patients in two age categories (≥70
Externí odkaz:
https://doaj.org/article/78cd5a99a5f94f51b2914a1d5f99a35b
Autor:
M.Lia Palomba, Manish R. Patel, Toby A. Eyre, Wojciech Jurczak, David John Lewis, Thomas Gastinne, Shuo Ma, Jonathon B. Cohen, Krish Patel, Jennifer R. Brown, Lydia Scarfò, Talha Munir, Ewa Lech-Marańda, Marc Hoffmann, Chaitra S. Ujjani, Bita Fakhri, Michael L. Wang, Koji Izutsu, Hirokazu Nagai, Constantine S. Tam, John F. Seymour, Joanna M. Rhodes, Julie M. Vose, Matthew McKinney, James N. Gerson, Minal A. Barve, Bryone J. Kuss, Youngil Koh, Wei Gao, Amy S. Ruppert, Richard A. Walgren, Donald E. Tsai, Binoj Nair, Katherine Bao, Anthony R. Mato, Chan Y. Cheah
Publikováno v:
Blood. 140:557-560
Autor:
Nirav N. Shah, Michael L. Wang, Jennifer R. Brown, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Zinzani, Alvaro J. Alencar, Thomas Gastinne, Paolo Ghia, Nicole Lamanna, Marc Hoffmann, Manish R. Patel, Ian W. Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Marańda, Bita Fakhri, Won-Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Lindsey E. Roeker, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Anthony R. Mato
Publikováno v:
Blood. 140:4127-4132
Autor:
Toby A Eyre, Nirav N Shah, Martin Dreyling, Wojciech Jurczak, Yucai Wang, Chan Y Cheah, Yuqin Song, Mitul Gandhi, Christopher Chay, Jeff Sharman, David J Andorsky, Hannah M Messersmith, Amy S Ruppert, Valerie A Muthig, Rodrigo Ito, Michael L Wang
Publikováno v:
Future Oncology. 18:3961-3969
Treatment with covalent Bruton tyrosine kinase inhibitors (BTKi) represents an important advance in the management of relapsed or refractory mantle cell lymphoma, but these treatments are not curative and many patients ultimately relapse. Pirtobrutin