Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Amy S. Conway"'
Autor:
Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, Miljan Kuljanin, Alan L. Leggett, Mikaela L. Mohardt, Amanda Robichaud, Amy S. Conway, Dennis L. Buckley, Joseph D. Mancias, James E. Bradner, Kimberly Stegmaier, Nathanael S. Gray
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
The dTAG system is used to rapidly deplete tagged target proteins in vitro and in vivo, but there are context- and protein-specific differences in its effectiveness. Here, the authors develop a second generation dTAG molecule that can degrade previou
Externí odkaz:
https://doaj.org/article/459b2972ed404c94bc46191739350a3c
Autor:
Nathaniel W. Mabe, Min Huang, Guillermo N. Dalton, Gabriela Alexe, Daniel A. Schaefer, Anna C. Geraghty, Amanda L. Robichaud, Amy S. Conway, Delan Khalid, Marius M. Mader, Julia A. Belk, Kenneth N. Ross, Michal Sheffer, Miles H. Linde, Nghi Ly, Winnie Yao, Maria Caterina Rotiroti, Benjamin A. H. Smith, Marius Wernig, Carolyn R. Bertozzi, Michelle Monje, Constantine S. Mitsiades, Ravindra Majeti, Ansuman T. Satpathy, Kimberly Stegmaier, Robbie G. Majzner
Publikováno v:
Nature Cancer. 3:976-993
Immunotherapy with anti-GD2 antibodies has advanced the treatment of children with high-risk neuroblastoma, but nearly half of patients relapse, and little is known about mechanisms of resistance to anti-GD2 therapy. Here, we show that reduced GD2 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c9eabc77d406c8f3cf09781745ec5a
https://doi.org/10.1038/s43018-022-00405-x
https://doi.org/10.1038/s43018-022-00405-x