Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amy Raber"'
Autor:
Satish Medicetty, Dominik Wiktor, Nicholas Lehman, Amy Raber, Zoran B. Popovic, Robert Deans, Anthony E. Ting, Marc S. Penn M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Acute myocardial infarction (AMI) results in ischemic damage and death of cardiomyocytes and loss of vasculature. Stem cell therapy has emerged as a potentially promising strategy for maximizing cardiac function following ischemic injury. Issues of c
Externí odkaz:
https://doaj.org/article/9a6ade1f35ce43a5918fae84016711cb
Autor:
Gregory G. Burrows, Robert J. Deans, Wouter Van't Hof, Nicholas Lehman, Richard T. Maziarz, Amy Raber, Karen Hunady
Publikováno v:
Cytotherapy. 16:566-575
Background aims Targeted recruitment of leukocytes to sites of inflammation is a crucial event in normal host defense against pathogens, and attachment to and rolling on activated endothelial cells is a prerequisite first step for eventual leukocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7cd52aeec9837cf5fb4a99341a166a
https://doi.org/10.1016/j.jcyt.2013.08.004
https://doi.org/10.1016/j.jcyt.2013.08.004
Autor:
Timothy Tree, Anthony E. Ting, Amy Raber, Robin R. Knight, Jef Pinxteren, James L. Reading, Robert J. Deans, Jennie H M Yang, Ania Skowera, Bart Vaes, Timothy E Allsopp, Sarah A. Busch, Shereen Sabbah
Publikováno v:
The Journal of Immunology. 190:4542-4552
A major goal of immunotherapy remains the control of pathogenic T cell responses that drive autoimmunity and allograft rejection. Adherent progenitor cells, including mesenchymal stromal cells (MSCs) and multipotent adult progenitor cells (MAPCs), re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c43d5c06c825102bc4d8fdb1462ec21
https://doi.org/10.4049/jimmunol.1202710
https://doi.org/10.4049/jimmunol.1202710
Autor:
Wouter Van't Hof, Amy Raber, Richard T. Maziarz, Philip R. Streeter, Robert J. Deans, Kelsey A. Mauch, Magdalena Kovacsovics-Bankowski, Mark R. Frey
Publikováno v:
Cellular Immunology. 255:55-60
Adherent bone marrow adult stem cells have been used in the treatment of GVHD. In this study, we investigate the capacity of a newly characterized population of stem cells, the Multipotent Adult Progenitor Cells (MAPC), to modulate acute GVHD. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb28d54b62846f9d48a087a7b4c41fc
https://doi.org/10.1016/j.cellimm.2008.10.004
https://doi.org/10.1016/j.cellimm.2008.10.004
Autor:
Phillip A. Wilmarth, Lien Timmerman, Robert J. Deans, Annelies Bogaerts, Larry L. David, Amy Raber, Jef Pinxteren, Gregory G. Burrows, Wouter Van't Hof, Ashok P. Reddy, Richard T. Maziarz, Valerie D. Roobrouck
Multipotent adult progenitor cells (MAPCs) are adult adherent stromal stem cells currently being assessed in clinical trials for acute graft versus host disease with demonstrated immunomodulatory capabilities and the potential to ameliorate detriment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1ec931289cf0704e512580a855d3aa
https://europepmc.org/articles/PMC4675500/
https://europepmc.org/articles/PMC4675500/
Autor:
Sherry Boozer, Jianmin Wang, John J. Harrington, Rob Perry, Stephen Rundlett, Nancy S Wang, Anthony E. Ting, Youssef L. Bennani, Kurt R. Brunden, Joel Danzig, James T. Anderson, Amy Raber, Steven M. Murphy, Tom Dent
Publikováno v:
Journal of Medicinal Chemistry. 48:2756-2758
Analogues of the natural product noscapine were synthesized, and their potential as antitumor agents were examined. The discovery of a novel regio- and stereoselective O-demethylation led to the synthesis of several O-alkylated analogues that induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b11ad7a70507a4380122e2da2db6572
https://doi.org/10.1021/jm0494220
https://doi.org/10.1021/jm0494220
Autor:
Jef Pinxteren, Wouter van't Hof, Amy Raber, Richard T. Maziarz, Gregory G. Burrows, Laura F. Newell, Phillip A. Wilmarth, Larry L. David, Ashok P. Reddy, Robert J. Deans, Annelies Bogaerts
Publikováno v:
Stem cells translational medicine. 2(10)
Multipotent adult progenitor cells (MAPCs) are adult adherent stromal stem cells currently being assessed in acute graft versus host disease clinical trials with demonstrated immunomodulatory capabilities and the potential to ameliorate detrimental a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3caad1accc7b9727f22398b40735a80
https://pubmed.ncbi.nlm.nih.gov/23981727
https://pubmed.ncbi.nlm.nih.gov/23981727
Autor:
Anthony E. Ting, Rochelle Cutrone, Nicholas Lehman, Robert Perry, Wouter Van't Hof, Robert J. Deans, Juliana Megan Woda, Amy Raber
Publikováno v:
Cytotherapy. 14(8)
Background aims. Clinical results from acute myocardial infarction (AMI) patients treated with MultiStem ® , a large-scale expanded adherent multipotent progenitor cell population (MAPC), have demonstrated a strong safety and benefi t profi le for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc61842bf3cf1de8a129e5f77aad6b0
https://pubmed.ncbi.nlm.nih.gov/22687190
https://pubmed.ncbi.nlm.nih.gov/22687190
Autor:
Sherry, Boozer, Nicholas, Lehman, Uma, Lakshmipathy, Brad, Love, Amy, Raber, Anirban, Maitra, Robert, Deans, Mahendra S, Rao, Anthony E, Ting
Publikováno v:
Journal of stem cells. 4(1)
The therapeutic benefits of adult adherent stem cells are currently being investigated in clinical trials for a variety of diseases. Data from initial clinical studies are promising and as a consequence of moving to later stage clinical studies, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::376f2e8a09f784e4e41cdc3ca7ea8fde
https://pubmed.ncbi.nlm.nih.gov/20498688
https://pubmed.ncbi.nlm.nih.gov/20498688
Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cells
Autor:
W. Van't Hof, Philip R. Streeter, Kelsey A. Mauch, Amy Raber, Robert J. Deans, Richard T. Maziarz, Magdalena Kovacsovics-Bankowski
Publikováno v:
Cytotherapy. 10(7)
Successful clinical development of novel cellular therapeutics requires the evaluation of clinical acute toxicity endpoints in scoring patient adverse events (AE) contributing to dose-limiting toxicity (DLT) for establishment of the maximum-tolerated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c83ed04ba97d79d3a1cee8de461738a
https://pubmed.ncbi.nlm.nih.gov/18985479
https://pubmed.ncbi.nlm.nih.gov/18985479