Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Amy R. Nelson"'
Autor:
Kassandra Kisler, Abhay P. Sagare, Divna Lazic, Sam Bazzi, Erica Lawson, Ching-Ju Hsu, Yaoming Wang, Anita Ramanathan, Amy R. Nelson, Zhen Zhao, Berislav V. Zlokovic
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-18 (2023)
Abstract Background PICALM is one of the most significant susceptibility factors for Alzheimer’s disease (AD). In humans and mice, PICALM is highly expressed in brain endothelium. PICALM endothelial levels are reduced in AD brains. PICALM controls
Externí odkaz:
https://doaj.org/article/2c6ff0ccb7ef45b8a95b5b676b04e74c
Autor:
Miranda K. Traylor, Allison J. Bauman, Napatsorn Saiyasit, Carl A. Frizell, Benjamin D. Hill, Amy R. Nelson, Joshua L. Keller
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
African American/Black individuals have been excluded from several lines of prominent neuroscience research, despite exhibiting disproportionately higher risk factors associated with the onset and magnitude of neurodegeneration. Therefore, the object
Externí odkaz:
https://doaj.org/article/7a62313bb73940fb851fdc7348f527fb
Autor:
Napatsorn Saiyasit, Evan-Angelo R. Butlig, Samantha D. Chaney, Miranda K. Traylor, Nanako A. Hawley, Ryleigh B. Randall, Hanna V. Bobinger, Carl A. Frizell, Franklin Trimm, Errol D. Crook, Mike Lin, Benjamin D. Hill, Joshua L. Keller, Amy R. Nelson
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Alzheimer’s disease and related dementias (ADRD) are an expanding worldwide crisis. In the absence of scientific breakthroughs, the global prevalence of ADRD will continue to increase as more people are living longer. Racial or ethnic minority grou
Externí odkaz:
https://doaj.org/article/cb9fe15b670346d8b518eaee24f239b2
Autor:
Kassandra Kisler, Abhay P. Sagare, Divna Lazic, Sam Bazzi, Erica Lawson, Ching-Ju Hsu, Yaoming Wang, Anita Ramanathan, Amy R. Nelson, Zhen Zhao, Berislav V. Zlokovic
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/65bb2a9c85dd493b909afe9f749dc436
Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer’s Disease
Autor:
Amy R. Nelson
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is the most common form of dementia. It was first described more than a century ago, and scientists are acquiring new data and learning novel information about the disease every day. Although there are nuances and details c
Externí odkaz:
https://doaj.org/article/fe0a3712ce1346c0a9b4531f08446a59
Autor:
Amy R. Nelson, Meghana A. Sagare, Yaoming Wang, Kassandra Kisler, Zhen Zhao, Berislav V. Zlokovic
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Brains depend on blood flow for the delivery of oxygen and nutrients essential for proper neuronal and synaptic functioning. French physiologist Rouget was the first to describe pericytes in 1873 as regularly arranged longitudinal amoeboid cells on c
Externí odkaz:
https://doaj.org/article/e8dddcae75f446d48d4b07898e99fcb2
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 11 (2019)
Locus coeruleus (LC) provides the sole source of noradrenergic (NA) innervation to hippocampus, and it undergoes significant degeneration early in Alzheimer’s disease (AD). Norepinephrine (NE) modulates synaptic transmission and plasticity at hippo
Externí odkaz:
https://doaj.org/article/d679b9e532234d3fbd7e4ec255d8b7c8
Publikováno v:
Frontiers in Aging Neuroscience, Vol 7 (2015)
Amyloid beta (Aβ) homeostasis in the brain is governed by its production and clearance mechanisms. An imbalance in this homeostasis results in pathological accumulations of cerebral Aβ, a characteristic of Alzheimer’s disease (AD). While Aβ may
Externí odkaz:
https://doaj.org/article/55f1bee2fe944d7d8461fd02e34f1a8f
Autor:
Lisa Ann Kirk Wiese, Allison Gibson, Marc Aaron Guest, Amy R. Nelson, Raven Weaver, Aditi Gupta, Owen Carmichael, Jordan P. Lewis, Allison Lindauer, Samantha Loi, Rachel Peterson, Kylie Radford, Elizabeth K. Rhodus, Christina G. Wong, Megan Zuelsdorff, Ladan Ghazi Saidi, Esmeralda Valdivieso‐Mora, Sanne Franzen, Caitlin N. Pope, Timothy S. Killian, Hom L. Shrestha, Patricia C. Heyn, Ted Kheng Siang Ng, Beth Prusaczyk, Samantha John, Ambar Kulshreshtha, Julia L. Sheffler, Lilah Besser, Valerie Daniel, Magdalena I. Tolea, Justin Miller, Christine Musyimi, Jon Corkey, Veronica Yank, Christine L Williams, Zahra Rahemi, JuYoung Park, Sheryl Magzamen, Robert L. Newton, Candace Harrington, Jason D. Flatt, Sonakshi Arora, Sarah Walter, Percy Griffin, Ganesh M. Babulal
Publikováno v:
Alzheimer's & Dementia.
INTRODUCTION: Individuals living in rural communities are at heightened risk for Alzheimer's disease and related dementias (ADRD), which parallels other persistent place-based health disparities. Identifying multiple potentially modifiable risk facto
Publikováno v:
Alzheimer's & Dementia. 18