Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Amy R Noe"'
Autor:
Barnabas G. Williams, Lloyd D. W. King, David Pulido, Doris Quinkert, Amelia M. Lias, Sarah E. Silk, Robert J. Ragotte, Hannah Davies, Jordan R. Barrett, Kirsty McHugh, Cassandra A. Rigby, Daniel G. W. Alanine, Lea Barfod, Michael W. Shea, Li An Cowley, Rebecca A. Dabbs, David J. Pattinson, Alexander D. Douglas, Oliver R. Lyth, Joseph J. Illingworth, Jing Jin, Cecilia Carnrot, Vinayaka Kotraiah, Jayne M. Christen, Amy R. Noe, Randall S. MacGill, C. Richter King, Ashley J. Birkett, Lorraine A. Soisson, Katherine Skinner, Kazutoyo Miura, Carole A. Long, Matthew K. Higgins, Simon J. Draper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Reticulocyte-binding protein homologue 5 (RH5), a leading blood-stage Plasmodium falciparum malaria vaccine target, interacts with cysteine-rich protective antigen (CyRPA) and RH5-interacting protein (RIPR) to form an essential heterotrimeri
Externí odkaz:
https://doaj.org/article/c0357f954cd04ff984155d03439a386e
Autor:
Jasmine Marie Corbin, Bryce Isao Hashimoto, Kalimuthu eKaruppanan, Zachary Ryan Kyser, Liying eWu, Brian A Roberts, Amy R Noe, Raymond L Rodriguez, Karen Ann McDonald, Somen eNandi
Publikováno v:
Frontiers in Plant Science, Vol 7 (2016)
An active and tetrameric form of recombinant butyrylcholinesterase (BChE), a large and complex human enzyme, was produced via semicontinuous operation in a transgenic rice cell suspension culture. After transformation of rice callus and screening of
Externí odkaz:
https://doaj.org/article/ef411b5b7be94f5a8d46ac1c8b2f2900
Autor:
Amy R Noe, Diego Espinosa, Xiangming Li, Jordana G A Coelho-Dos-Reis, Ryota Funakoshi, Steve Giardina, Hongfan Jin, Diane M Retallack, Ryan Haverstock, Jeffrey R Allen, Thomas S Vedvick, Christopher B Fox, Steven G Reed, Ramses Ayala, Brian Roberts, Scott B Winram, John Sacci, Moriya Tsuji, Fidel Zavala, Gabriel M Gutierrez
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107764 (2014)
The circumsporozoite protein (CSP) of Plasmodium falciparum is a major surface protein, which forms a dense coat on the sporozoite's surface. Preclinical research on CSP and clinical evaluation of a CSP fragment-based RTS, S/AS01 vaccine have demonst
Externí odkaz:
https://doaj.org/article/3b2cec5996cd4a34b37c5b812f74c3d6
Autor:
Julie Healer, Jennifer K. Thompson, Karen L. Mackwell, Cecille D. Browne, Benjamin A. Seager, Anna Ngo, Kym N. Lowes, Sarah E. Silk, David Pulido, Lloyd D. W. King, Jayne M. Christen, Amy R. Noe, Vinayaka Kotraiah, Paul J. Masendycz, Rajkannan Rajagopalan, Leanne Lucas, Marianne M. Stanford, Lorraine Soisson, Carter Diggs, Robin Miller, Susan Youll, Kaye Wycherley, Simon J. Draper, Alan F. Cowman
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
BackgroundRH5 is the leading vaccine candidate for the Plasmodium falciparum blood stage and has shown impact on parasite growth in the blood in a human clinical trial. RH5 binds to Ripr and CyRPA at the apical end of the invasive merozoite form, and
Externí odkaz:
https://doaj.org/article/84dce22671ea4ea78f35e3a24b9607b4
Autor:
Vinayaka Kotraiah, Timothy W. Phares, Frances E. Terry, Pooja Hindocha, Sarah E. Silk, Carolyn M. Nielsen, Leonard Moise, Kenneth D. Tucker, Rebecca Ashfield, William D. Martin, Anne S. De Groot, Simon J. Draper, Gabriel M. Gutierrez, Amy R. Noe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The hurdles to effective blood stage malaria vaccine design include immune evasion tactics used by the parasite such as redundant invasion pathways and antigen variation among circulating parasite strains. While blood stage malaria vaccine developmen
Externí odkaz:
https://doaj.org/article/2deefbdc3cd44a348943f7cc2e674f49
Autor:
Amy R. Noe, Frances E. Terry, Brian C. Schanen, Emily Sassano, Pooja Hindocha, Timothy W. Phares, Leonard Moise, Jayne M. Christen, Kenneth D. Tucker, Vinayaka Kotraiah, Donald R. Drake, William D. Martin, Anne S. De Groot, Gabriel M. Gutierrez
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
An effective malaria vaccine must prevent disease in a range of populations living in regions with vastly different transmission rates and protect against genetically-diverse Plasmodium falciparum (Pf) strains. The protective efficacy afforded by the
Externí odkaz:
https://doaj.org/article/fef88e5b7d31426fb7aaaf98a3dfc878
Autor:
Kenneth D. Tucker, Brian C. Schanen, Timothy W. Phares, Emily Sassano, Frances E. Terry, Pooja Hindocha, Leonard Moise, Vinayaka Kotraiah, William D. Martin, Anne S. De Groot, Donald R. Drake, Gabriel M. Gutierrez, Amy R. Noe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunization with radiation-attenuated sporozoites (RAS) has been shown to protect against malaria infection, primarily through CD8 T cell responses, but protection is limited based on parasite strain. Therefore, while CD8 T cells are an ideal effect
Externí odkaz:
https://doaj.org/article/839ca3ed3a7e4d638b64a64cda4d2406
Autor:
Michelle N. Wykes, Deshapriya S. Karunarathne, Gabriel M. Gutierrez, James Pannucci, Marc Mansour, Amy R. Noe, Moriya Tsuji, Vinayaka Kotraiah, Peter Buontempo, Timothy W. Phares, Cecille D. Browne, Jing Huang
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
The blockade of programmed cell death-1 (PD1) and its ligand PDL1 has been proven to be a successful immunotherapy against several cancers. Similar to cancer, PD1 contributes to the establishment of several chronic infectious diseases, including mala
Autor:
Anne S. De Groot, Leonard Moise, Frances Terry, Andres H. Gutierrez, Pooja Hindocha, Guilhem Richard, Daniel Fredric Hoft, Ted M. Ross, Amy R. Noe, Yoshimasa Takahashi, Vinayaka Kotraiah, Sarah E. Silk, Carolyn M. Nielsen, Angela M. Minassian, Rebecca Ashfield, Matt Ardito, Simon J. Draper, William D. Martin
Publikováno v:
Frontiers in immunology, 11:442
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Computational vaccinology includes epitope mapping, antigen selection, and immunogen design using computational tools. Tools that facilitate the in silico prediction of immune response to biothreats, emerging infectious diseases, and cancers can acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c2200c905c633823195ea371519434
https://repository.publisso.de/resource/frl:6421959
https://repository.publisso.de/resource/frl:6421959
Autor:
Carolin Loos, Carole A. Long, Saul N. Faust, Anna Goodman, David Pulido, Fay L. Nugent, Jordan R. Barrett, Robert Smith, Katherine J. Ellis, Tatiana Ogrina, Ashlin R. Michell, Raquel Lopez Ramon, M Datoo, Galit Alter, Thomas A. Rawlinson, Michael Marks, Megan Baker, Lorraine Soisson, Nick J. Edwards, Eleanor Berrie, Ababacar Diouf, Angela M. Minassian, Willem A. de Jongh, Sarah E. Silk, Rebecca Ashfield, Doris Quinkert, D Silman, Michael T. White, Carter L. Diggs, Alison M. Lawrie, Nathan J Brendish, Alexander D. Douglas, Iona J. Taylor, Hector Maxwell-Scott, Yrene Themistocleous, Ruth O. Payne, Jonathan K. Fallon, Kazutoyo Miura, Rahul Batra, Lea Barfod, Antonio Querol-Rubiera, Celia Mitton, P M Folegatti, Ian D. Poulton, Jing Jin, Carolyn M. Nielsen, Fernando Ramos Lopez, Karen Bisnauthsing, Amy R. Noe, Simon J. Draper
Publikováno v:
Med (New York, N.y.)
Summary Background Development of an effective vaccine against the pathogenic blood-stage infection of human malaria has proved challenging, and no candidate vaccine has affected blood-stage parasitemia following controlled human malaria infection (C