Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Amy R MacQueen"'
Autor:
Bart Nieuwenhuis, Amanda C Barber, Rachel S Evans, Craig S Pearson, Joachim Fuchs, Amy R MacQueen, Susan vanErp, Barbara Haenzi, Lianne A Hulshof, Andrew Osborne, Raquel Conceicao, Tasneem Z Khatib, Sarita S Deshpande, Joshua Cave, Charles Ffrench‐Constant, Patrice D Smith, Klaus Okkenhaug, Britta J Eickholt, Keith R Martin, James W Fawcett, Richard Eva
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Abstract Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regenerati
Externí odkaz:
https://doaj.org/article/774319b15576431a80d815b1901eaee3
Autor:
Charles ffrench-Constant, Craig S Pearson, Amanda C. Barber, Keith R Martin, Bart Nieuwenhuis, Tasneem Z Khatib, Patrice D. Smith, Rachel S Evans, Lianne A Hulshof, Joachim Fuchs, Richard Eva, Klaus Okkenhaug, Raquel D. Conceição, Sarita S Deshpande, Britta J. Eickholt, Andrew Osborne, Joshua Cave, James W. Fawcett, Barbara Haenzi, Susan van Erp, Amy R. MacQueen
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp n/a-n/a (2020)
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Nieuwenhuis, B, Barber, A C, Evans, R S, Pearson, C S, Fuchs, J, MacQueen, A R, van Erp, S, Haenzi, B, Hulshof, L A, Osborne, A, Conceicao, R, Khatib, T Z, Deshpande, S S, Cave, J, Ffrench-Constant, C, Smith, P D, Okkenhaug, K, Eickholt, B J, Martin, K R, Fawcett, J W & Eva, R 2020, ' PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS ', EMBO Molecular Medicine, vol. 12, no. 8, e11674 . https://doi.org/10.15252/emmm.201911674
EMBO Molecular Medicine, 12. Wiley-Blackwell
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Autor:
Bart, Nieuwenhuis, Amanda C, Barber, Rachel S, Evans, Craig S, Pearson, Joachim, Fuchs, Amy R, MacQueen, Susan, van Erp, Barbara, Haenzi, Lianne A, Hulshof, Andrew, Osborne, Raquel, Conceicao, Tasneem Z, Khatib, Sarita S, Deshpande, Joshua, Cave, Charles, Ffrench-Constant, Patrice D, Smith, Klaus, Okkenhaug, Britta J, Eickholt, Keith R, Martin, James W, Fawcett, Richard, Eva
Publikováno v:
EMBO Molecular Medicine
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Autor:
Joachim Fuchs, Raquel D. Conceição, Bart Nieuwenhuis, Barabara Haenzi, James W. Fawcett, Charles ffrench-Constant, Klaus Okkenhaug, Patrice D. Smith, Susan van Erp, Richard Eva, Keith R Martin, Britta J. Eickholt, Andrew Osborne, Craig S Pearson, Rachel S Evans, Amy R. MacQueen, Amanda C. Barber, Sarita S Deshpande, Joshua Cave, Lianne A Hulshof
Peripheral nervous system (PNS) neurons support axon regeneration into adulthood, whereas central nervous system (CNS) neurons lose regenerative ability after development. To better understand this decline whilst aiming to improve regeneration, we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3489aa2318f5f2428a7995198533cf1b
https://doi.org/10.1101/787994
https://doi.org/10.1101/787994
Autor:
Michael Lahn, Amy R. MacQueen, Lars van der Veen, Karolina Niewola, Giuditta Viticchiè, Pritom Shah, Ian R. Powley, Zoë Johnson, Francesca Finotello
Publikováno v:
Cancer Research. 80:666-666
The inhibition of PI3Kδ preferentially targets regulatory T cells and myeloid derived suppressor cells, breaking tumour-induced immune tolerance and restoring anti-tumour immunity. Bioinformatics and protein expression studies have shown that PIK3CD
Autor:
Amy R. MacQueen, Michael Lahn, Anna Tsapara, L. Van der Veen, Pritom Shah, Evangelia A. Papakonstanti, Zoë Johnson
Publikováno v:
Annals of Oncology. 30:vii27
Background Inhibiting PI3Kδ preferentially targets regulatory T cells and myeloid derived suppressor cells, breaking tumour-induced immune tolerance and restoring anti-tumour immunity. Bioinformatics and protein expression studies have shown that PI
Autor:
Michael Lahn, Lars van der Veen, Katherine Ewings, Pritom Shah, Anna Tsapara, Zoë Johnson, Evangelia A. Papakonstanti, Amy R. MacQueen
Publikováno v:
Cancer Research. 79:2692-2692
The Class I Phosphatidylinositol-4,5-bisphosphate 3-kinase (PI3K) family is an attractive target class for the treatment of hematological and solid malignancies. In addition to the direct effects of PI3Kδ inhibition on B cell malignancies, inhibitin
Publikováno v:
The Journal of Immunology Author Choice
PI3Ks regulate diverse immune cell functions by transmitting intracellular signals from Ag, costimulatory receptors, and cytokine receptors to control cell division, differentiation, survival, and migration. In this study, we report the effect of inh