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pro vyhledávání: '"Amy Patricia Moore"'
Autor:
Amy Patricia Moore, Thach-Giao Truong, Kenneth Ted Thurn, Scott Thomas, Charles J. Ryan, Thierry Marie Jahan, Steven G. DuBois, John K. Chan, Hope S. Rugo, Eric Andrew Collisson, Paromita Raha, Stephanie Chen, Anne Reinert, Adil Daud, Pamela N. Munster
Publikováno v:
Journal of Clinical Oncology. 30:3058-3058
3058 Background: Preclinical and clinical data suggest pre-exposure of cancer cells to a histone deacetylase inhibitor (HDACi) potentiates topoisomerase inhibitors. HDACi-induced histone acetylation and chromatin modulation facilitates DNA access and