Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Amy Orr"'
Publikováno v:
eLife, Vol 6 (2017)
At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the
Externí odkaz:
https://doaj.org/article/fa380fd6b0cf429fbdcfa5fab9ea62c7
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/23cf9930ac914536b1dc17719f692ca2
Publikováno v:
eLife, Vol 3 (2014)
Like other intracellular fusion events, the homotypic fusion of yeast vacuoles requires a Rab GTPase, a large Rab effector complex, SNARE proteins which can form a 4-helical bundle, and the SNARE disassembly chaperones Sec17p and Sec18p. In addition
Externí odkaz:
https://doaj.org/article/5b216bf6b34f472fbd5bd1d01bf42885
Autor:
Dawn Liu Holford, Angelo Fasce, Katy Tapper, Miso Demko, Stephan Lewandowsky, Ulrike Hahn, Christoph M. Abels, Ahmed K. Al-Rawi, Sameer Naseef Binnazir Alladin, T. Sonia Boender, Hendrik Bruns, Helen Fischer, Christian Gilde, Paul H. P. Hanel, Stefan Michael Herzog, Astrid Kause, Sune Lehmann, Matthew Nurse, Caroline Amy Orr, Niccolo Pescetelli, Maria Petrescu, Sunita Sah, Philipp Schmid, Miroslav Sirota, Marlene Wulf
Publikováno v:
Science Communication
Effective science communication is challenging when scientific messages are informed by a continually updating evidence base and must often compete against misinformation. We argue that we need a new program of science communication as collective int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da3ce5d9b806f1ea01570d99a36a98ae
https://hdl.handle.net/21.11116/0000-000D-0DF0-6
https://hdl.handle.net/21.11116/0000-000D-0DF0-6
Autor:
Amy Orr, William Wickner
Publikováno v:
Molecular Biology of the Cell. 34
Using reconstituted fusion with all purified proteins and defined lipids, four targets for PI3P regulation are reported: recruitment of the Qc-SNARE, trans-SNARE assembly between membranes, protection of SNARE complexes from the chaperones Sec17 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bdaa6c71654bfc9722b9c760945bb10
https://doi.org/10.1091/mbc.e22-10-0486
https://doi.org/10.1091/mbc.e22-10-0486
Autor:
Amy Orr, William Wickner
Publikováno v:
Molecular biology of the cell. 33(13)
Membrane fusion is driven by Sec17, Sec18, and SNARE zippering. Sec17 bound to SNAREs promotes fusion through its membrane-proximal N-terminal apolar loop domain. At its membrane-distal end, Sec17 serves as a high-affinity receptor for Sec18. At that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2df0f621ea11410a6068714dd0b625c
https://pubmed.ncbi.nlm.nih.gov/36103252
https://pubmed.ncbi.nlm.nih.gov/36103252
Publikováno v:
Molecular biology of the cell. 33(5)
Membrane fusion requires tethers, SNAREs of R, Qa, Qb, and Qc families, and chaperones of the SM, Sec17/SNAP, and Sec18/NSF families. SNAREs have N-domains, SNARE domains that zipper into 4-helical RQaQbQc coiled coils, a short juxtamembrane (Jx) dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7873885f31c1717052c6376fd5283a4
https://pubmed.ncbi.nlm.nih.gov/35171720
https://pubmed.ncbi.nlm.nih.gov/35171720
Autor:
Amy Orr-Ewing
Your relationship with God is just a psychological crutch. Belief in God is dangerous. I used to believe, but I've given it all up. Is God real? Is it possible to know anything, let alone know him? Why do bad things happen to people who worship this
Autor:
Amy Orr-Ewing
The mother of God is often portrayed as a passive figure, yet Mary is described in Luke's gospel as a woman who exercised choice, questioned things, reflected, responded, spoke up, and demonstrated great faith. Mary had a voice. This unique Advent de