Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amy Nouanesengsy"'
Autor:
Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A. Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C. Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, Katherine Prieto, Stephanie A. Bueler, Sawsan Youssef, Sindy Liao-Chan, Jacob Glanville, Natasha Christie-Holmes, Samira Mubareka, Scott D. Gray-Owen, John L. Rubinstein, Bebhinn Treanor, Jean-Philippe Julien
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, the authors combine three different antibody specificities and an Fc domain on a single multivalent molecule, resulting in high neutralization activity despite viral sequence variability.
Externí odkaz:
https://doaj.org/article/21239c53aca444dbbc85f54151271ca5
Autor:
Varsha Bhakta, Mostafa Hamada, Amy Nouanesengsy, Jessica Lapierre, Darian L. Perruzza, William P. Sheffield
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Coagulation Factor XIa (FXIa) is an emerging target for antithrombotic agent development. The M358R variant of the serpin alpha-1 antitrypsin (AAT) inhibits both FXIa and other proteases. Our aim was to enhance the specificity of AAT M358R f
Externí odkaz:
https://doaj.org/article/4657582d6d9b43608bea58dc7f4701aa
Autor:
Darian L. Perruzza, Amy Nouanesengsy, Jessica Lapierre, William P. Sheffield, Mostafa Hamada, Varsha Bhakta
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Coagulation Factor XIa (FXIa) is an emerging target for antithrombotic agent development. The M358R variant of the serpin alpha-1 antitrypsin (AAT) inhibits both FXIa and other proteases. Our aim was to enhance the specificity of AAT M358R for FXIa.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca0bea8f6121c4e8cf5b8b52684a339
http://europepmc.org/articles/PMC7946950
http://europepmc.org/articles/PMC7946950
Autor:
Samir Benlekbir, Katherine Prieto, Krithika Muthuraman, Furkan Guvenc, Edurne Rujas, Jean-Philippe Julien, Natasha Christie-Holmes, Jacob Glanville, Gregory A. Wasney, Patrick Budylowski, Samira Mubareka, Sawsan Youssef, Anthony Semesi, Amy Nouanesengsy, Clare Burn Aschner, Scott D. Gray-Owen, John L. Rubinstein, Hong Cui, Stephanie A. Bueler, Yong Zi Tan, Taylor Sicard, Sindy Liao-Chan, Bebhinn Treanor, Iga Kucharska, Jocelyn C. Newton, Tiantian Zhao
Publikováno v:
Addi. Archivo Digital para la Docencia y la Investigación
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature Communications
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Nature Communications
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
SARS-CoV-2, the virus responsible for COVID-19, has caused a global pandemic. Antibodies can be powerful biotherapeutics to fight viral infections. Here, we use the human apoferritin protomer as a modular subunit to drive oligomerization of antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5722cdeb8e6fa77a947f721a9d3ec314
http://hdl.handle.net/10810/52013
http://hdl.handle.net/10810/52013
Autor:
Katherine Prieto, Tiantian Zhao, Krithika Muthuraman, Taylor Sicard, Natasha Christie-Holmes, Jean-Philippe Julien, Iga Kucharska, Yong Zi Tan, Stephanie A. Bueler, Amy Nouanesengsy, Edurne Rujas, Scott D. Gray-Owen, Samir Benlekbir, Sindy Liao-Chan, Hong Cui, Patrick Budylowski, Samira Mubareka, Bebhinn Treanor, Anthony Semesi, Furkan Guvenc, Jacob Glanville, Jocelyn C. Newton, Sawsan Youssef, John L. Rubinstein, Gregory A. Wasney
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes Coronavirus Disease 2019 (COVID-19), has caused a global pandemic. Antibodies are powerful biotherapeutics to fight viral infections; however, discovery of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bfcc7fa3984d84cc6c489f06f8ae88
http://hdl.handle.net/10261/222437
http://hdl.handle.net/10261/222437
Autor:
Rujas, Edurne, Kucharska, Iga, Tan, Yong Zi, Benlekbir, Samir, Cui, Hong, Zhao, Tiantian, Wasney, Gregory A., Budylowski, Patrick, Guvenc, Furkan, Newton, Jocelyn C., Sicard, Taylor, Semesi, Anthony, Muthuraman, Krithika, Nouanesengsy, Amy, Aschner, Clare Burn, Prieto, Katherine, Bueler, Stephanie A., Youssef, Sawsan, Liao-Chan, Sindy, Glanville, Jacob
Publikováno v:
Nature Communications; 6/16/2021, Vol. 12 Issue 1, p1-12, 12p