Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Amy Manney"'
Autor:
Adela Buzescu, Amy Manney, Jianing Zeng, Mark E. Arnold, Hong Wu Shen, Yan J Zhang, LaKenya Williams, Kimberly Voronin, Naiyu Zheng, Anne-Françoise Aubry, Carrie Xu, Alban Allentoff, William Warner
Publikováno v:
Analytica Chimica Acta. 916:42-51
To quantify a therapeutic PEGylated protein in monkey serum as well as to monitor its potential in vivo instability and methionine oxidation, a novel ultra high performance liquid chromatography-high resolution mass spectrometric (UHPLC-HRMS) assay w
Autor:
Vangipuram S. Rangan, Amy Manney, Mark Saewert, Ang Liu, Binodh DeSilva, Donna Dail, Jennifer Cummings, Renuka Pillutla, Alex Kozhich, Heather Myler, Chetana Rao, Jian Wang, Brian K. Hoffpauir
Publikováno v:
Bioanalysis. 8:519-531
Background: The bioanalytical strategy for antibody–drug conjugates (ADC) includes multiple integrated measurements of pharmacologically relevant ADC. Methods & results: Three ligand-binding assays were validated for the measurement of total antibo
Autor:
Jian Wang, Mei-Chen Sung, Binodh DeSilva, Robert Neely, Jennifer Cummings, Donna Dail, Steven P. Piccoli, John Lute, Heather Myler, Alexander T. Kozhich, Richard L. Wong, Thomas D. Kempe, Wendy Freebern, Anne-Françoise Aubry, Renuka Pillutla, Heather E. Vezina, Mark E. Arnold, Vangipuram S. Rangan, Mark Saewert, Bonnie Wang, Frank Zambito, David Passmore, Amy Manney, Shrikant Deshpande, Huidong Gu, Ang Liu
Publikováno v:
Bioanalysis. 7:1569-1582
Background: The bioanalytical strategy for antibody–drug conjugates (ADC) includes numerous measurements integrally designed to provide comprehensive characterization of PK, PD and immunogenicity. This manuscript describes the utilization of reagen