Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Amy M. Spiegel"'
Autor:
Jason Aldred, Eric Freire-Alvarez, Alexander V. Amelin, Angelo Antonini, Bruno Bergmans, Filip Bergquist, Manon Bouchard, Kumar Budur, Camille Carroll, K. Ray Chaudhuri, Susan R. Criswell, Erik H. Danielsen, Florin Gandor, Jia Jia, Thomas E. Kimber, Hideki Mochizuki, Weining Z. Robieson, Amy M. Spiegel, David G. Standaert, Saritha Talapala, Maurizio F. Facheris, Victor S. C. Fung
Publikováno v:
Neurology and Therapy, Vol 12, Iss 6, Pp 1937-1958 (2023)
Abstract Introduction Foslevodopa/foscarbidopa, a soluble formulation of levodopa/carbidopa (LD/CD) prodrugs for the treatment of Parkinson’s disease (PD), is administered as a 24-hour/day continuous subcutaneous infusion (CSCI) with a single infus
Externí odkaz:
https://doaj.org/article/3c28527413ce4845845ba7b0a3dbeb25
Autor:
Victor S.C. Fung, Jason Aldred, Martha P. Arroyo, Filip Bergquist, Agnita J.W. Boon, Manon Bouchard, Sarah Bray, Sara Dhanani, Maurizio F. Facheris, Nahome Fisseha, Eric Freire-Alvarez, Robert A. Hauser, Anna Jeong, Jia Jia, Pavnit Kukreja, Michael J. Soileau, Amy M. Spiegel, Saritha Talapala, Arjun Tarakad, Enrique Urrea-Mendoza, Jorge Zamudio, Rajesh Pahwa
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 10, Iss , Pp 100239- (2024)
Background: As Parkinson's disease (PD) advances, management is challenged by an increasingly variable and inconsistent response to oral dopaminergic therapy, requiring special considerations by the provider. Continuous 24 h/day subcutaneous infusion
Externí odkaz:
https://doaj.org/article/ee4b4d82effb4c59b7e2610de99a7111
Autor:
Jason Aldred, Eric Freire-Alvarez, Alexander V. Amelin, Angelo Antonini, Bruno Bergmans, Filip Bergquist, Manon Bouchard, Kumar Budur, Camille Carroll, K. Ray Chaudhuri, Susan R. Criswell, Erik H. Danielsen, Florin Gandor, Jia Jia, Thomas E. Kimber, Hideki Mochizuki, Weining Z. Robieson, Amy M. Spiegel, David G. Standaert, Saritha Talapala, Maurizio F. Facheris, Victor S. C. Fung
Publikováno v:
Neurology and Therapy, Vol 12, Iss 6, Pp 1959-1960 (2023)
Externí odkaz:
https://doaj.org/article/fbd221fdae034683822ddee813fd4949
Publikováno v:
Hippocampus. 24:1300-1307
Episodic memory impairment due to aging has been linked to hippocampal dysfunction. Evidence exists for alterations in specific circuits within the hippocampal system that are closely coupled to individual differences in the presence and severity of
Publikováno v:
Journal of Comparative Neurology. 521:3508-3523
Hippocampal interneuron populations are reportedly vulnerable to normal aging. The relationship between interneuron network integrity and age-related memory impairment, however, has not been tested directly. That question was addressed in the present
Autor:
Peter R. Rapp, Rebecca P. Haberman, Amy M. Spiegel, Adrian G. Palacios, Michela Gallagher, Peter A. Angeli
Publikováno v:
Alzheimer's & Dementia. 12
Publikováno v:
The Journal of Comparative Neurology. 520:1318-1326
For many years, aging was thought to be accompanied by significant decreases in total neuron number across multiple brain regions. However, this view was revised with the advent of modern quantification methods, and it is now widely accepted that the
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 21(10)
Epigenetic modifications of chromatin structure provide a mechanistic interface for gene–environment interactions that impact the individualization of health trajectories across the lifespan. A growing body of research indicates that dysfunctional
Publikováno v:
Hippocampus. 24(11)
Episodic memory impairment due to aging has been linked to hippocampal dysfunction. Evidence exists for alterations in specific circuits within the hippocampal system that are closely coupled to individual differences in the presence and severity of