Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Amy M. McHenry"'
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154577 (2016)
Duffy binding protein region II (DBPII) is a promising vaccine candidate against vivax malaria. However, polymorphisms of DBPII are the major obstacle to designing a successful vaccine. Here, we examined whether anti-DBPII antibodies from individual
Externí odkaz:
https://doaj.org/article/f461844138be4cb8bf86b53b9a7023e2
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20192 (2011)
Invasion of human red blood cells by Plasmodium merozoites is vital for replication and survival of the parasite and, as such, is an attractive target for therapeutic intervention. Merozoite invasion is mediated by specific interactions between paras
Externí odkaz:
https://doaj.org/article/4a4cc829f41348c98e0dab5c631eaf35
Autor:
John H. Adams, Siriruk Changrob, Amy M. McHenry, Myat Htut Nyunt, Jetsumon Sattabongkot, Eun-Taek Han, Patchanee Chootong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
The major challenge in designing a protective Duffy binding protein region II (DBPII)-based vaccine against blood-stage vivax malaria is the high number of polymorphisms in critical residues targeted by binding-inhibitory antibodies. Here, longevity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cfa18f308adcdebd3b1df47adae90c
http://europepmc.org/articles/PMC5973932
http://europepmc.org/articles/PMC5973932
Autor:
Rosalind E. Howes, Marcelo U. Ferreira, Jia Xianli, Asim A. Siddiqui, Peter A. Zimmerman, Christopher L. King, Brian T. Grimberg, Mônica da Silva-Nunes, Lior J. Greenberg, Amy M. McHenry, John H. Adams
Publikováno v:
Proceedings of the National Academy of Sciences. 108:20113-20118
Plasmodium vivax (Pv) is a major cause of human malaria and is increasing in public health importance compared with falciparum malaria. Pv is unique among human malarias in that invasion of erythrocytes is almost solely dependent on the red cell's su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f1ec1e9cd8644d71d6763b453d51fc
https://doi.org/10.1073/pnas.1109621108
https://doi.org/10.1073/pnas.1109621108
Autor:
John W. Barnwell, John H. Adams, Jennifer L. Cole-Tobian, Francis B. Ntumngia, Amy M. McHenry, Christopher L. King
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 80:218-227
Plasmodium vivax Duffy binding protein (DBP) is vital for parasite development, thereby making this molecule a good vaccine candidate. Preclinical development of a P. vivax vaccine often involves use of primate models prior to testing efficacy in hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96728ea5881fc3ad655eb297c39908b7
https://doi.org/10.4269/ajtmh.2009.80.218
https://doi.org/10.4269/ajtmh.2009.80.218
Autor:
Jesse Schloegel, Samantha J. Barnes, Miriam T. George, Francis B. Ntumngia, Amy M. McHenry, John H. Adams
Molecules that play a role inPlasmodiummerozoite invasion of host red blood cells represent attractive targets for blood-stage vaccine development against malaria. InPlasmodium vivax, merozoite invasion of reticulocytes is mediated by the Duffy bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2367d661846a22b8eae3433dc9c6f649
https://europepmc.org/articles/PMC4178564/
https://europepmc.org/articles/PMC4178564/
Autor:
John H. Adams, Amy M. McHenry, Jetsumon Sattabongkot, Francis B. Ntumngia, Patchanee Chootong
Publikováno v:
Parasitology international. 63(6)
Plasmodium vivax Duffy binding protein II (DBPII) plays an important role in reticulocyte invasion and is a potential vaccine candidate against vivax malaria. However, polymorphisms in DBPII are a challenge for the successful design of a broadly prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53917f0c32d1bed9cd359f04643ddc2b
https://pubmed.ncbi.nlm.nih.gov/25108177
https://pubmed.ncbi.nlm.nih.gov/25108177
Autor:
Samantha J. Barnes, Francis B. Ntumngia, John H. Adams, Jesse Schloegel, Miriam T. George, Amy M. McHenry, Sandra Kennedy
The Duffy binding protein (DBP) of Plasmodium vivax is vital for host erythrocyte invasion. DBP region II (DBPII) contains critical residues for receptor recognition and anti-DBPII antibodies have been shown to inhibit erythrocyte binding and invasio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7f5d738c8f560eb4604eb537c515f2
https://europepmc.org/articles/PMC4497540/
https://europepmc.org/articles/PMC4497540/
Autor:
Jetsumon Sattabongkot, John H. Adams, Amy M. McHenry, Sudarat Wongkidakarn, Patchanee Chootong
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0154577 (2016)
PLoS ONE, Vol 11, Iss 5, p e0154577 (2016)
Duffy binding protein region II (DBPII) is a promising vaccine candidate against vivax malaria. However, polymorphisms of DBPII are the major obstacle to designing a successful vaccine. Here, we examined whether anti-DBPII antibodies from individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6d0dbd8310f36f6df6a54ffdc3afae
https://doi.org/10.1371/journal.pone.0154577
https://doi.org/10.1371/journal.pone.0154577
Autor:
Christopher L. King, Samantha J. Barnes, Jesse Schloegel, Francis B. Ntumngia, Amy M. McHenry, Sanjay Singh, John H. Adams
Publikováno v:
Infection and immunity. 80(3)
The Duffy binding protein (DBP) is a vital ligand for Plasmodium vivax blood-stage merozoite invasion, making the molecule an attractive vaccine candidate against vivax malaria. Similar to other blood-stage vaccine candidates, DBP allelic variation e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce23a4cfd138166ae90bdb9a87933cf6
https://pubmed.ncbi.nlm.nih.gov/22215740
https://pubmed.ncbi.nlm.nih.gov/22215740