Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Amy M. Matteini"'
Autor:
Sara M. Willems, Daniel J. Wright, Felix R. Day, Katerina Trajanoska, Peter K. Joshi, John A. Morris, Amy M. Matteini, Fleur C. Garton, Niels Grarup, Nikolay Oskolkov, Anbupalam Thalamuthu, Massimo Mangino, Jun Liu, Ayse Demirkan, Monkol Lek, Liwen Xu, Guan Wang, Christopher Oldmeadow, Kyle J. Gaulton, Luca A. Lotta, Eri Miyamoto-Mikami, Manuel A. Rivas, Tom White, Po-Ru Loh, Mette Aadahl, Najaf Amin, John R. Attia, Krista Austin, Beben Benyamin, Søren Brage, Yu-Ching Cheng, Paweł Cięszczyk, Wim Derave, Karl-Fredrik Eriksson, Nir Eynon, Allan Linneberg, Alejandro Lucia, Myosotis Massidda, Braxton D. Mitchell, Motohiko Miyachi, Haruka Murakami, Sandosh Padmanabhan, Ashutosh Pandey, Ioannis Papadimitriou, Deepak K. Rajpal, Craig Sale, Theresia M. Schnurr, Francesco Sessa, Nick Shrine, Martin D. Tobin, Ian Varley, Louise V. Wain, Naomi R. Wray, Cecilia M. Lindgren, Daniel G. MacArthur, Dawn M. Waterworth, Mark I. McCarthy, Oluf Pedersen, Kay-Tee Khaw, Douglas P. Kiel, GEFOS Any-Type of Fracture Consortium, Yannis Pitsiladis, Noriyuki Fuku, Paul W. Franks, Kathryn N. North, Cornelia M. van Duijn, Karen A. Mather, Torben Hansen, Ola Hansson, Tim Spector, Joanne M. Murabito, J. Brent Richards, Fernando Rivadeneira, Claudia Langenberg, John R. B. Perry, Nick J. Wareham, Robert A. Scott
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Hand grip strength as a proxy of muscular fitness is a clinical predictor of mortality and morbidity. In a large-scale GWA study, the authors find 16 robustly associated genetic loci that highlight roles in muscle fibre structure and function, neuron
Externí odkaz:
https://doaj.org/article/c79d45da5079409b8be2da8ab36a65af
Autor:
Steven R. Cummings, Dan Mellström, Ian J. Deary, Jennifer A. Smith, David Karasik, Dena G. Hernandez, Beverly G Windham, David C. Liewald, Maria Nethander, D. S. Knopman, Sharon L.R. Kardia, Velandai Srikanth, Rotem Vered, Albert V. Smith, Joanne M. Murabito, Magnus Karlsson, Alice M. Arnold, Tamara B. Harris, Joris Deelen, Philip L. De Jager, Janie Corley, Andrew D. Johnson, Hieab H.H. Adams, Jos N. van der Geest, Neeta Parimi, A.B. Newman, Gail Davies, David R. Weir, Yongmei Liu, Russell Thomson, John M. Starr, David A. Bennett, Joe Verghese, Lei Yu, Aron S. Buchman, Jessica D. Faul, Gil Atzmon, Gregory J. Tranah, Myriam Fornage, Douglas P. Kiel, Marian Beekman, Alison Pattie, Vilmundur Gudnason, Claes Ohlsson, Toshiko Tanaka, Lenore J. Launer, Daniel S. Evans, Vincent J. A. Verlinden, Michele L. Callisaya, Jeanine J. Houwing-Duistermaat, Stephen Turner, Luigi Ferrucci, Albert Hofman, Simon P. Mooijaart, Danielle Gutman, Rebekah McWhirter, M. Arfan Ikram, André G. Uitterlinden, Wei Zhao, Jeremy D. Walston, Amy M. Matteini, Denis A. Evans, Matthijs Moed, Stefania Bandinelli, Danny Ben-Avraham, John D. Eicher, Thomas H. Mosley, Eline Slagboom, Kathryn L. Lunetta, Lital Sharvit
Publikováno v:
Ben-Avraham, D, Karasik, D, Verghese, J, Lunetta, K L, Smith, J A, Eicher, J D, Vered, R, Deelen, J, Arnold, A M, Buchman, A S, Tanaka, T, Faul, J D, Nethander, M, Fornage, M, Adams, H H, Matteini, A M, Callisaya, M L, Smith, A V, Yu, L, De Jager, P L, Evans, D A, Gudnason, V, Hofman, A, Pattie, A, Corley, J, Launer, L J, Knopman, D S, Parimi, N, Turner, S T, Bandinelli, S, Beekman, M, Gutman, D, Sharvit, L, Mooijaart, S P, Liewald, D C, Houwing-Duistermaat, J J, Ohlsson, C, Moed, M, Verlinden, V J, Mellström, D, van der Geest, J N, Karlsson, M, Hernandez, D, McWhirter, R, Liu, Y, Thomson, R, Tranah, G J, Uitterlinden, A G, Weir, D R, Zhao, W, Starr, J M, Johnson, A D, Ikram, M A, Bennett, D A, Cummings, S R, Deary, I J, Harris, T B, Kardia, S L R, Mosley, T H, Srikanth, V K, Windham, B G, Newman, A B, Walston, J D, Davies, G, Evans, D S, Slagboom, E P, Ferrucci, L, Kiel, D P, Murabito, J M & Atzmon, G 2017, ' The complex genetics of gait speed : Genome-wide meta-analysis approach ', Aging, vol. 9, no. 1, pp. 209-246 . https://doi.org/10.18632/aging.101151
Aging-Us, 9(1), 209-246. Impact Journals LLC
Aging (Albany NY)
Aging, 9(1), 209-246
Aging-Us, 9(1), 209-246. Impact Journals LLC
Aging (Albany NY)
Aging, 9(1), 209-246
Emerging evidence suggests that the basis for variation in late-life mobility is attributable, in part, to genetic factors, which may become increasingly important with age. Our objective was to systematically assess the contribution of genetic varia
Autor:
John D. Eicher, Dena G. Hernandez, Maria Nethander, Russell Thomson, Thomas H. Mosley, Amy M. Matteini, Lenore J. Launer, Gil Atzmon, A.B. Newman, Dan Mellström, Lital Sharvit, Stephen T. Turner, Joe Verghese, Simon P. Mooijaart, Douglas P. Kiel, Jessica D. Faul, Stefania Bandinelli, Jeremy D. Walston, D. S. Knopman, John M. Starr, David R. Weir, Wei Zhao, Jennifer A. Smith, Sharon L.R. Kardia, Ian J. Deary, Beverly G Windham, Joris Deelen, Alice M. Arnold, Denis A. Evans, Eline Slagboom, Gail Davies, Danielle Gutman, Rotem Vered, David C. Liewald, Magnus Karlsson, Alison Pattie, Kathryn L. Lunetta, Velandai Srikanth, Vilmundur Gudnason, Janie Corley, Joanne M. Murabito, Luigi Ferrucci, Vincent J. A. Verlinden, Michele L. Callisaya, Tamara B. Harris, Danny Ben-Avraham, Jos N. van der Geest, Lei Yu, David Karasik, Philip L. De Jager, Gregory J. Tranah, Toshiko Tanaka, Jeanine J. Houwing-Duistermaat, Aron S. Buchman, Hieab H.H. Adams, Myriam Fornage, Albert V. Smith, Matthijs Moed, Claes Ohlsson, Andrew D. Johnson, Marian Beekman, André G. Uitterlinden, Neeta Parimi, M. Arfan Ikram, Steven R. Cummings, Albert Hofman, Rebekah McWhirter, Yongmei Liu, Daniel S. Evans, David A. Bennett
Publikováno v:
Aging (Albany NY)
Emerging evidence suggests that the basis for variation in late-life mobility is attributable, in part, to genetic factors, which may become increasingly important with age. Our objective was to systematically assess the contribution of genetic varia
Autor:
Qunyuan Zhang, Candace M. Kammerer, Mary K. Wojczynski, Jennifer A. Brody, Anne B. Newman, Joanne M. Murabito, Amy M. Matteini, M. Michael Barmada, Kathryn L. Lunetta, Kaare Christensen, E. Warwick Daw, Thomas T. Perls, Michael A. Province, Jason L. Sanders, Ryan L. Minster, Jatinder Singh, Alice M. Arnold
Publikováno v:
Minster, R L, Sanders, J L, Singh, J, Kammerer, C M, Barmada, M M, Matteini, A M, Zhang, Q, Wojczynski, M K, Daw, E W, Brody, J A, Arnold, A M, Lunetta, K L, Murabito, J M, Christensen, K, Perls, T T, Province, M A & Newman, A B 2015, ' Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 70, no. 8, pp. 1003-1008 . https://doi.org/10.1093/gerona/glv006
BACKGROUND: The Healthy Aging Index (HAI) is a tool for measuring the extent of health and disease across multiple systems. METHODS: We conducted a genome-wide association study and a genome-wide linkage analysis to map quantitative trait loci associ
Autor:
Faith Pangilinan, Amy M. Matteini, Sally P. Stabler, Emma L. Kurnat-Thoma, Ginette A. Pepper, Bob Wong, Lawrence C. Brody, Jack M. Guralnik
Publikováno v:
Biological Research For Nursing. 17:444-454
Cobalamin (vitamin B12) deficiency is a subtle progressive clinical disorder, affecting nearly 1 in 5 individuals > 60 years old. This deficiency is produced by age-related decreases in nutrient absorption, medications that interfere with vitamin B12
Autor:
Ethan M. Lange, Luigi Ferrucci, Toshiko Tanaka, Aravinda Chakravarti, Jin Li, Leslie A. Lange, M. D. Fallin, Amy M. Matteini, Mary L. Biggs, Russel Tracy, Bruce M. Psaty, Yunfei Wang, Stefania Bandinelli, Dan E. Arking, Alexander P. Reiner, Jeremy D. Walston
Publikováno v:
Cytokine. 65:10-16
Activation of inflammatory pathways measured by serum inflammatory markers such as interleukin-18 (IL-18) and interleukin-1 receptor antagonist (IL-1ra) is strongly associated with the progression of chronic disease states in older adults. Given that
Autor:
Ingrid B. Borecki, Anne B. Newman, Amy M. Matteini, Richard Mayeux, Ryan L. Minster, Kaare Christensen, Jeremy D. Walston, Jason L. Sanders, Jatinder Singh, Thomas T. Perls
Publikováno v:
Sanders, J L, Singh, J, Minster, R L, Walston, J D, Matteini, A M, Christensen, K, Mayeux, R, Borecki, I B, Perls, T, Newman, A B & Long Life Family Study Research Group 2016, ' Association Between Mortality and Heritability of the Scale of Aging Vigor in Epidemiology ', American Geriatrics Society. Journal, vol. 64, no. 8, pp. 1679-1683 . https://doi.org/10.1111/jgs.14190
OBJECTIVES: To investigate the association between mortality and heritability of a rescaled Fried frailty index, the Scale of Aging Vigor in Epidemiology (SAVE), to determine its value for genetic analyses. DESIGN: Longitudinal, community-based cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985d8e460a4fffed322ac0446b35507f
https://portal.findresearcher.sdu.dk/da/publications/29b698d2-1bd6-4f6e-815b-8322291c1785
https://portal.findresearcher.sdu.dk/da/publications/29b698d2-1bd6-4f6e-815b-8322291c1785
Autor:
Wen-Chi Chou, Yi-Hsiang Hsu, Birte Holtfreter, Irina Gillham-Nasenya, Lies Lahousse, Russell Thomson, Uwe Völker, Aron S. Buchman, Albert V. Smith, Steven R. Cummings, Jeremy D. Walston, Douglas P. Kiel, Sudha Seshadri, Kristine Yaffe, Toshiko Tanaka, Gregory J. Tranah, Sharon L.R. Kardia, André G. Uitterlinden, Denis A. Evans, Lori B. Chibinik, Daniel S. Evans, Vilmundur Gudnason, Jennifer A. Smith, Jerome I. Rotter, Michele L. Callisaya, Lorna M. Lopez, Dan E. Arking, Stephen B. Kritchevsky, Henry Völzke, Gil Atzmon, Anne B. Newman, B. Gwen Windham, Philip L. De Jager, Massimo Mangino, Melissa E. Garcia, Albert Hofman, Luigi Ferrucci, Thomas Kocher, Kathryn L. Lunetta, John M. Starr, Kurt Lohman, Lei Yu, Tim D. Spector, Andrew D. Johnson, Alexander Teumer, David R. Weir, Velandai Srikanth, Kristin Siggeirsdottir, John D. Eicher, Fernando Rivadeneira, Alice M. Arnold, Gail Davies, Wei Zhao, Joanne M. Murabito, David A. Bennett, M. Carola Zillikens, Wei Vivian Zhuang, Tamara B. Harris, Amy M. Matteini, Bruce M. Psaty, David Karasik, Till Ittermann, Jessica D. Faul, Ian J. Deary, David C. Liewald, Joseph M. Zmuda, Yongmei Liu
Publikováno v:
Matteini, AM; Tanaka, T; Karasik, D; Atzmon, G; Chou, W-C; Eicher, JD; et al.(2016). GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. AGING CELL, 15(5), 792-800. doi: 10.1111/acel.12468. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8t07c76j
AGING CELL
Aging Cell
Aging cell, vol 15, iss 5
Aging Cell, 15(5), 792-800. Wiley-Blackwell Publishing Ltd
Matteini, A M, Tanaka, T, Karasik, D, Atzmon, G, Chou, W C, Eicher, J D, Johnson, A D, Arnold, A M, Callisaya, M L, Davies, G, Evans, D S, Holtfreter, B, Lohman, K, Lunetta, K L, Mangino, M, Smith, A V, Smith, J A, Teumer, A, Yu, L, Arking, D E, Buchman, A S, Chibinik, L B, DeJager, P L, Evans, D A, Faul, J D, Garcia, M E, Gillham-Nasenya, I, Gudnason, V, Hofman, A, Hsu, Y H, Ittermann, T, Lahousse, L, Liewald, D C, Liu, Y, Lopez, L, Rivadeneira, F, Rotter, J I, Siggeirsdottir, K, Starr, J M, Thomson, R, Tranah, G J, Uitterlinden, A G, Völker, U, Völzke, H, Weir, D R, Yaffe, K, Zhao, W, Zhuang, W V, Zmuda, J M, Bennett, D A, Cummings, S R, Deary, I J, Ferrucci, L, Harris, T B, Kardia, S L R, Kocher, T, Kritchevsky, S B, Psaty, B M, Seshadri, S, Spector, T D, Srikanth, V K, Windham, B G, Zillikens, M C, Newman, A B, Walston, J D, Kiel, D P & Murabito, J M 2016, ' GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium ', AGING CELL, vol. 15, no. 5, pp. 792-800 . https://doi.org/10.1111/acel.12468
AGING CELL
Aging Cell
Aging cell, vol 15, iss 5
Aging Cell, 15(5), 792-800. Wiley-Blackwell Publishing Ltd
Matteini, A M, Tanaka, T, Karasik, D, Atzmon, G, Chou, W C, Eicher, J D, Johnson, A D, Arnold, A M, Callisaya, M L, Davies, G, Evans, D S, Holtfreter, B, Lohman, K, Lunetta, K L, Mangino, M, Smith, A V, Smith, J A, Teumer, A, Yu, L, Arking, D E, Buchman, A S, Chibinik, L B, DeJager, P L, Evans, D A, Faul, J D, Garcia, M E, Gillham-Nasenya, I, Gudnason, V, Hofman, A, Hsu, Y H, Ittermann, T, Lahousse, L, Liewald, D C, Liu, Y, Lopez, L, Rivadeneira, F, Rotter, J I, Siggeirsdottir, K, Starr, J M, Thomson, R, Tranah, G J, Uitterlinden, A G, Völker, U, Völzke, H, Weir, D R, Yaffe, K, Zhao, W, Zhuang, W V, Zmuda, J M, Bennett, D A, Cummings, S R, Deary, I J, Ferrucci, L, Harris, T B, Kardia, S L R, Kocher, T, Kritchevsky, S B, Psaty, B M, Seshadri, S, Spector, T D, Srikanth, V K, Windham, B G, Zillikens, M C, Newman, A B, Walston, J D, Kiel, D P & Murabito, J M 2016, ' GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium ', AGING CELL, vol. 15, no. 5, pp. 792-800 . https://doi.org/10.1111/acel.12468
Decline in muscle strength with aging is an important predictor of health trajectory in the elderly. Several factors, including genetics, are proposed contributors to variability in muscle strength. To identify genetic contributors to muscle strength
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442a8e586c75fe926db58f1f13af071e
https://mural.maynoothuniversity.ie/17199/
https://mural.maynoothuniversity.ie/17199/
Autor:
Jatinder Singh, Nicole Schupf, Tanushree Prasad, Anne B. Newman, Yongmei Liu, Robert M. Boudreau, Kaare Christensen, Candace M. Kammerer, Amy M. Matteini
Publikováno v:
Singh, J, Schupf, N, Boudreau, R, Matteini, A M, Prasad, T, Newman, A B, Liu, Y, Christensen, K & Kammerer, C M 2015, ' Association of Aging-Related Endophenotypes With Mortality in 2 Cohort Studies : the Long Life Family Study and the Health, Aging and Body Composition Study ', American Journal of Epidemiology, vol. 182, no. 11, pp. 926-935 . https://doi.org/10.1093/aje/kwv143
One method by which to identify fundamental biological processes that may contribute to age-related disease and disability, instead of disease-specific processes, is to construct endophenotypes comprising linear combinations of physiological measures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc023048937e002743b1b5b7e2bd7cc
https://portal.findresearcher.sdu.dk/da/publications/236ee473-e2f5-4442-b90e-b118c8eb8275
https://portal.findresearcher.sdu.dk/da/publications/236ee473-e2f5-4442-b90e-b118c8eb8275
Autor:
Jeremy D. Walston, Kaare Christensen, Richard Mayeux, Anne B. Newman, Anatoli I. Yashin, Nicole Schupf, Graham Barr, Konstantin G. Arbeev, Amy M. Matteini, M. Daniele Fallin, Candace M. Kammerer
Publikováno v:
Matteini, A M, Fallin, M D, Kammerer, C M, Schupf, N, Yashin, A I, Christensen, K, Arbeev, K G, Barr, G, Mayeux, R, Newman, M-A & Walston, J D 2010, ' Heritability Estimates of Endophenotypes of Long and Health Life: The Long Life Family Study ', The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 65A, no. 12, pp. 1375-1379 . https://doi.org/10.1093/gerona/glq154
BACKGROUND: Identification of gene variants that contribute to exceptional survival may provide critical biologic information that informs optimal health across the life span. METHODS: As part of phenotype development efforts for the Long Life Family