Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Amy M. Martinson"'
Autor:
Eileen L. Brady, Olivia Prado, Fredrik Johansson, Shannon N. Mitchell, Amy M. Martinson, Elaheh Karbassi, Hans Reinecke, Charles E. Murry, Jennifer Davis, Kelly R. Stevens
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Developing vascular networks that integrate with the host circulation and support cells engrafted within engineered tissues remains a key challenge in tissue engineering. Most previous work in this field has focused on developing new methods
Externí odkaz:
https://doaj.org/article/e4434aa2b47f42da8157dc8c892d9650
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 986-998 (2020)
Current cell transplantation techniques are hindered by small graft size, requiring high cell doses to achieve therapeutic cardiac remuscularization. Enhancing the proliferation of transplanted human embryonic stem cell-derived cardiomyocytes (hESC-C
Externí odkaz:
https://doaj.org/article/8e82704e86c448fdbb29b86791afed47
Autor:
Sonette Steczina, Jennifer Davis, Charles E. Murry, Darrian Bugg, Amy M. Martinson, Kevin M. Beussman, Danny El-Nachef, Nathan J. Sniadecki
Publikováno v:
Circulation
Publikováno v:
International journal of cardiology and cardiovascular diseases. 1(1)
Histological analysis of fluorescently labeled tissues has been a critical tool to understand molecular organization
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss, Pp 986-998 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Current cell transplantation techniques are hindered by small graft size, requiring high cell doses to achieve therapeutic cardiac remuscularization. Enhancing the proliferation of transplanted human embryonic stem cell-derived cardiomyocytes (hESC-C
Autor:
Meredith A. Redd, Ying Zheng, Wei Wei, Yuliang Wang, Nicole Zeinstra, Ruikang K. Wang, Charles E. Murry, Wan Qin, Amy M. Martinson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
Vascularization and efficient perfusion are long-standing challenges in cardiac tissue engineering. Here we report engineered perfusable microvascular constructs, wherein human embryonic stem cell-derived endothelial cells (hESC-ECs) are seeded both
Autor:
Charles E. Murry, Amy M. Martinson, Katie A Mitzelfelt, Sanjay Sinha, Laure Gambardella, L. Ong, Alessandro Bertero, Maria Colzani
Publikováno v:
The Journal of Heart and Lung Transplantation. 40:S299-S300
Purpose Myocardial infarction (MI) results in permanent cardiomyocyte loss, frequently leading to heart failure with 50% 5-year mortality. At subacute time points following MI, animal studies have shown ‘remuscularization’ of the damaged heart wi
In addition to increasing the risk of an initial myocardial infarction (MI), diabetes increases the risk of a recurrent MI. Previous work suggests that an experimental MI can accelerate atherosclerosis via monocytosis. To test if diabetes and experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f32d66fbac0aff900121349889cf04
https://doi.org/10.2337/figshare.12670325
https://doi.org/10.2337/figshare.12670325
Publikováno v:
Diabetes
In addition to increasing the risk of an initial myocardial infarction (MI), diabetes increases the risk of a recurrent MI. Previous work suggests that an experimental MI can accelerate atherosclerosis via monocytosis. To test whether diabetes and ex
Autor:
Hans Reinecke, Amy M. Martinson, Charles E. Murry, Jill J. Weyers, Benjamin Van Biber, Timothy C. Cox, Stephen M. Schwartz, Jagadambika J. Gunaje, William M. Mahoney
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0227780 (2020)
PLoS ONE
PLoS ONE
The engraftment of human stem cell-derived cardiomyocytes (hSC-CMs) is a promising treatment for remuscularizing the heart wall post-infarction, but it is plagued by low survival of transplanted cells. We hypothesize that this low survival rate is du