Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Amy M. Kleman"'
Autor:
Matthew H. Kemm, Leslie E. Landree, Jagan N. Thupari, Francis P. Kuhajda, Jayson Hyun, Susan M. Medghalchi, Khadija Daniels, Erica Plummer, Andrea Aplasca, Susan Aja, Amy M. Kleman, Gabriele V. Ronnett, Craig A. Townsend, Aravinda Vadlamudi, Jill M. McFadden, Timothy H. Moran
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 294:R352-R361
Inhibition of brain carnitine palmitoyl-transferase-1 (CPT-1) is reported to decrease food intake and body weight in rats. Yet, the fatty acid synthase (FAS) inhibitor and CPT-1 stimulator C75 produces hypophagia and weight loss when given to rodents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::501cd28916cdcec594873dcd0ed7cff6
https://doi.org/10.1152/ajpregu.00862.2006
https://doi.org/10.1152/ajpregu.00862.2006
Publikováno v:
Neuroscience Letters. 423:200-204
Understanding the mechanisms that regulate feeding is critical to the development of therapeutic interventions for obesity. Many studies indicate that enzymes within fatty acid metabolic pathways may serve as targets for pharmacological tools to trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e562dc463b19f95aeadf7d43a86983a
https://doi.org/10.1016/j.neulet.2007.06.056
https://doi.org/10.1016/j.neulet.2007.06.056
Publikováno v:
Cell Cycle. 6:1077-1089
Neuronal stem cell expansion and differentiation is a process involving stages of proliferation and maturation governed by the sequential and combinatorial exposure of cells to extrinsic factors. The olfactory epithelium is an excellent model to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732a548f0b235d65fa9b600a830c79ad
https://doi.org/10.4161/cc.6.9.4132
https://doi.org/10.4161/cc.6.9.4132
Autor:
Amy M. Kleman, Benjamin Holt, Stephanie L.H. Zeiger, Joshua D. Brooks, Jacquelynn E. Brown, Erik S. Musiek, BethAnn McLaughlin, Jane C. Hettinger, Ginger L. Milne, Jason D. Morrow
Publikováno v:
ResearcherID
Stroke is the leading cause of adult disability in the U.S. and is now recognized as a global epidemic. There are currently no FDA-approved drugs to block the cell death that results from oxygen and glucose deprivation. This void in clinical medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66569f53bb3b9acc2be7e55f4e8b06f1
https://europepmc.org/articles/PMC3679093/
https://europepmc.org/articles/PMC3679093/
Adenosine monophosphate-activated protein kinase (AMPK) senses metabolic stress and integrates diverse physiological signals to restore energy balance. Multiple functions are indicated for AMPK in the CNS. While all neurons sense their own energy sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c3795ef57edee70e093470a0a17696
https://europepmc.org/articles/PMC2925428/
https://europepmc.org/articles/PMC2925428/
Publikováno v:
Journal of neuroscience methods. 167(2)
Understanding the mechanisms that govern neuronal responses to oxidative and metabolic stress is essential for therapeutic intervention. In vitro modeling is an important approach for these studies, as the metabolic environment influences neuronal re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825976fd90a3717edc84329525f29642
https://pubmed.ncbi.nlm.nih.gov/17936912
https://pubmed.ncbi.nlm.nih.gov/17936912