Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Amy M. Chinn"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Chronic decreases in the second messenger cyclic AMP (cAMP) occur in numerous settings, but how cells compensate for such decreases is unknown. We have used a unique system—murine dendritic cells (DCs) with a DC-selective depletion of the heterotri
Externí odkaz:
https://doaj.org/article/de126dcb359a4e1ba9d7a7370df0e1e0
Publikováno v:
Physiological Reports, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract Chronic hypoxia from diseases in the lung, such as pulmonary hypertension, pulmonary fibrosis, and chronic obstructive pulmonary disease, can increase pulmonary vascular resistance, resulting in hypertrophy and dysfunction of the right ventr
Externí odkaz:
https://doaj.org/article/7ca406ab943c4b068e59585c4b3484dc
Autor:
Amy M. Chinn, Paul A. Insel
Publikováno v:
Br J Pharmacol
Allergic diseases are immune disorders that are a global health problem, affecting a large portion of the world's population. Allergic asthma is a heterogeneous disease that alters the biology of the airway. A substantial portion of patients with ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646a9d6b3334899dfbd957db1fe3b465
https://doi.org/10.1111/bph.15095
https://doi.org/10.1111/bph.15095
Publikováno v:
Frontiers in pharmacology. 13
Chronic decreases in the second messenger cyclic AMP (cAMP) occur in numerous settings, but how cells compensate for such decreases is unknown. We have used a unique system—murine dendritic cells (DCs) with a DC-selective depletion of the heterotri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a14196649f3d1d3df75769bb660c9
https://pubmed.ncbi.nlm.nih.gov/35387344
https://pubmed.ncbi.nlm.nih.gov/35387344
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a45c8c8b1a7b8a70eb93b7255452838
https://doi.org/10.1096/fasebj.2019.33.1_supplement.836.8
https://doi.org/10.1096/fasebj.2019.33.1_supplement.836.8
Autor:
Shu Z. Wiley, Matthew W. Gorr, Paul A. Insel, Amy M. Chinn, Alexander V. Michkov, Krishna Sriram, Cristina Salmerón
Publikováno v:
Trends Pharmacol Sci
Trends in pharmacological sciences, vol 40, iss 6
Trends in pharmacological sciences, vol 40, iss 6
G protein-coupled receptors (GPCRs) are targets for ∼35% of approved drugs but only ∼15% of the ∼800 human GPCRs are currently such targets. GPCRomics, the use of unbiased, hypothesis-generating methods [e.g., RNA-sequencing (RNA-seq)], with ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ea9e4c5d7096bac67509e05c91c549
https://pubmed.ncbi.nlm.nih.gov/31078319
https://pubmed.ncbi.nlm.nih.gov/31078319
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a07363cbad0b37d84906e4844566dc19
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.13
https://doi.org/10.1096/fasebj.2018.32.1_supplement.686.13
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d275e7d3e6ebb1644bd356fafaadfddc
https://doi.org/10.1096/fasebj.2018.32.1_supplement.864.15
https://doi.org/10.1096/fasebj.2018.32.1_supplement.864.15
Autor:
Wanda Jones, Amy M. Chinn, John Henry J. Scott, Jeff Chinn, Marlon L. Walker, Konrad Rykaczewski
Publikováno v:
ACS Nano. 5:9746-9754
Nanoparticles adsorbed onto the surface of a drop can fully encapsulate the liquid, creating a robust and durable soft solid with superhydrophobic characteristics referred to as a liquid marble. Artificially created liquid marbles have been studied f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d552572e5db671922e6ea06ee9bf59a
https://doi.org/10.1021/nn203268e
https://doi.org/10.1021/nn203268e
Autor:
Aaron C. Overland, Rebecca M. Lynch, Thalia McCann, Krishna Sriram, Alexander C. Zambon, Lingzhi Zhang, Shu Zhou, Amy M. Chinn, Ross Corriden, Nakon Aroonsakool, Daniel McDonald, Alexander V. Michkov, Aaron N. Snead, Fiona Murray, Paul A. Insel, Andrea Wilderman
Publikováno v:
Molecular pharmacology, vol 88, iss 1
G protein-coupled receptors (GPCRs), the largest family of signaling receptors in the human genome, are also the largest class of targets of approved drugs. Are the optimal GPCRs (in terms of efficacy and safety) currently targeted therapeutically? E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f926ba0aac33c881ba081260253d579f
https://europepmc.org/articles/PMC4468643/
https://europepmc.org/articles/PMC4468643/
