Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amy M. Buckley"'
Autor:
Susan A. Kennedy, Maria E. Morrissey, Margaret R. Dunne, Fiona O’Connell, Clare T. Butler, Mary-Clare Cathcart, Amy M. Buckley, Brian J. Mehigan, John O. Larkin, Paul McCormick, Breandán N. Kennedy, Jacintha O’Sullivan
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Colorectal cancer (CRC) is the second most common cause of cancer-related mortality worldwide with one in every five patients diagnosed with metastatic CRC (mCRC). In mCRC cases, the 5-year survival rate remains at approximately 1
Externí odkaz:
https://doaj.org/article/8a55b1ac41ea46598fac7e188fb44562
Autor:
Amy M. Buckley, Margaret R. Dunne, Maria E. Morrissey, Susan A. Kennedy, Aoife Nolan, Maria Davern, Emma K. Foley, Niamh Clarke, Joanne Lysaght, Narayanasamy Ravi, Dermot O’Toole, Finbar MacCarthy, John V. Reynolds, Breandán N. Kennedy, Jacintha O’Sullivan
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survi
Externí odkaz:
https://doaj.org/article/e0a0a6fa4475406c8c5b27eb5adbbaa8
Autor:
Aisling B. Heeran, Helen P. Berrigan, Croí E. Buckley, Heleena Moni Bottu, Orla Prendiville, Amy M. Buckley, Niamh Clarke, Noel E. Donlon, Timothy S. Nugent, Michael Durand, Cara Dunne, John O. Larkin, Brian Mehigan, Paul McCormick, Lorraine Brennan, Niamh Lynam-Lennon, Jacintha O'Sullivan
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100882- (2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of rad
Externí odkaz:
https://doaj.org/article/24e333a5a2ae47b7a8972b8cd7d23308
Autor:
Aisling B. Heeran, Jessica McCready, Margaret R. Dunne, Noel E. Donlon, Timothy S. Nugent, Anshul Bhardwaj, Kathleen A. J. Mitchelson, Amy M. Buckley, Narayanasamy Ravi, Helen M. Roche, John V. Reynolds, Niamh Lynam-Lennon, Jacintha O’Sullivan
Publikováno v:
Metabolites, Vol 11, Iss 11, p 768 (2021)
Oesophageal adenocarcinoma (OAC) is an exemplar model of obesity-associated cancer. Previous work in our group has demonstrated that overweight/obese OAC patients have better responses to neoadjuvant therapy, but the underlying mechanisms are unknown
Externí odkaz:
https://doaj.org/article/4b17fa7c7aa34e3fb57f33a4372a340f
Autor:
Amy M. Buckley, Becky AS. Bibby, Margaret R. Dunne, Susan A. Kennedy, Maria B. Davern, Breandán N. Kennedy, Stephen G. Maher, Jacintha O’Sullivan
Publikováno v:
Pharmaceuticals, Vol 12, Iss 1, p 33 (2019)
Cisplatin (cis-diamminedichloroplatinum) is widely used for the treatment of solid malignancies; however, the development of chemoresistance hinders the success of this chemotherapeutic in the clinic. This study provides novel insights into the molec
Externí odkaz:
https://doaj.org/article/8dc5795466d74bd3a581849084cb514b
Autor:
Aoife Nolan, Emma K. Foley, Narayanasamy Ravi, John V. Reynolds, Jacintha O'Sullivan, Susan Kennedy, Maria E Morrissey, Margaret R. Dunne, Maria Davern, F MacCarthy, Breandán N. Kennedy, Joanne Lysaght, Dermot O'Toole, Amy M. Buckley, Niamh Clarke
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f5a251c1f9766184e12079e599b204
https://doaj.org/article/e0a0a6fa4475406c8c5b27eb5adbbaa8
https://doaj.org/article/e0a0a6fa4475406c8c5b27eb5adbbaa8
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 17:298-313
Radiotherapy is used in the treatment of approximately 50% of all malignancies including gastrointestinal cancers. Radiation can be given prior to surgery (neoadjuvant radiotherapy) to shrink the tumour or after surgery to kill any remaining cancer c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::864fc6a071092f68ccc61d978fea3caa
https://doi.org/10.1038/s41575-019-0247-2
https://doi.org/10.1038/s41575-019-0247-2
Autor:
Amy M. Buckley, Breandán N. Kennedy, William M. Gallagher, Ronan S. Doyle, Emer Conroy, Susan Kennedy, Clare T. Butler, Jacintha O'Sullivan
Publikováno v:
Oncotarget
Colorectal cancer (CRC) is the second leading cause of cancer associated deaths in developed countries. Cancer progression and metastatic spread is reliant on new blood vasculature, or angiogenesis. Tumour-related angiogenesis is regulated by pro- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb566c63fa1ee66590e00403264a0e4
http://europepmc.org/articles/PMC6557215
http://europepmc.org/articles/PMC6557215
Autor:
Amy M. Buckley, Fiona O'Connell, Margaret R. Dunne, J. O. Larkin, Paul McCormick, Maria E Morrissey, Clare T. Butler, Brian Mehigan, Jacintha O'Sullivan, Susan Kennedy, Mary-Clare Cathcart, Breandán N. Kennedy
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)
Background Colorectal cancer (CRC) is the second most common cause of cancer-related mortality worldwide with one in every five patients diagnosed with metastatic CRC (mCRC). In mCRC cases, the 5-year survival rate remains at approximately 14%, refle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e86ca4fca73f9eb9bde35a6c1cd9ed
https://doi.org/10.1186/s12885-020-07430-y
https://doi.org/10.1186/s12885-020-07430-y
Autor:
Orla Prendiville, Noel E Donlon, Cara Dunne, Croí E. Buckley, Helen P. Berrigan, Timothy Nugent, Lorraine Brennan, J. O. Larkin, Michael Durand, Niamh Lynam-Lennon, Heleena Moni Bottu, Amy M. Buckley, Aisling B Heeran, Brian Mehigan, Jacintha O'Sullivan, Niamh Clarke, Paul McCormick
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100882-(2021)
Locally advanced rectal cancer is treated with neoadjuvant-chemoradiotherapy, however only 22% of patients achieve a complete response. Resistance mechanisms are poorly understood. Radiation-induced Bystander Effect (RIBE) describes the effect of rad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7b36a639368d9167dde0b2fddde74d
http://europepmc.org/articles/PMC7586242
http://europepmc.org/articles/PMC7586242