Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Amy M Navratil"'
Autor:
Guangyuan Li, Isaac N Hayward, Brittany R Jenkins, Heather M Rothfuss, Coleman H Young, Marja T Nevalainen, Aaron Muth, Paul R Thompson, Amy M Navratil, Brian D Cherrington
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147503 (2016)
Peptidylarginine deiminases (PADs) post-translationally convert arginine into neutral citrulline residues. Our past work shows that PADs are expressed in the canine and murine mammary glands; however, the mechanisms regulating PAD expression and the
Externí odkaz:
https://doaj.org/article/cfff09e67e294f9fa049e27a7f9cd7cd
Autor:
Michael J Calderon, Adam G Ploegman, Brock Bailey, Deborah O Jung, Amy M Navratil, Buffy S Ellsworth
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128942 (2015)
FOXM1, a member of the forkhead box transcription factor family, plays a key role in cell cycling progression by regulating the expression of critical G1/S and G2/M phase transition genes. In vivo studies reveal that Foxm1 null mice have a 91% lethal
Externí odkaz:
https://doaj.org/article/78ba624a8ef942638fed184002948526
Autor:
Brian D. Cherrington, Baskaran Thyagarajan, Adithya Mohandass, Bryce Snow, Coleman H. Young, Venkatesh V. Nemmara, Paul R. Thompson, Stanley B DeVore, Amy M. Navratil
Publikováno v:
Reproduction (Cambridge, England)
Peptidylarginine deiminases (PAD) enzymes were initially characterized in uteri, but since then little research has examined their function in this tissue. PADs post-translationally convert arginine residues in target proteins to citrulline and are h
Autor:
Amanda O Christensen, Guangyuan Li, Coleman H Young, Bryce Snow, Shaihla A Khan, Stanley B DeVore, Sydney Edwards, Gerrit J Bouma, Amy M Navratil, Brian D Cherrington, Heather M Rothfuss
Publikováno v:
Biol Reprod
Citrullination, the post-translational modification of arginine residues, is catalyzed by the four catalytically active peptidylarginine deiminase (PAD or PADI) isozymes and alters charge to affect target protein structure and function. PADs were ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c4b3f42898b4df157fcc14a7f3faa5
https://europepmc.org/articles/PMC10248218/
https://europepmc.org/articles/PMC10248218/
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
Gonadotropes cells located in the anterior pituitary gland are critical for reproductive fitness. A rapid surge in the serum concentration of luteinizing hormone (LH) secreted by anterior pituitary gonadotropes is essential for stimulating ovulation
Autor:
Paul R. Thompson, Aaron Muth, Shaihla A. Khan, Brian S. Edwards, Amy M. Navratil, Brian D. Cherrington
Publikováno v:
Molecular Endocrinology. 30:1081-1091
Peptidylarginine deiminase (PAD) enzymes convert histone tail arginine residues to citrulline resulting in chromatin decondensation. Our previous work found that PAD isoforms are expressed in female reproductive tissues in an estrous cycle-dependent
Autor:
Do-Geun Kim, Mark S. Roberson, Amy M. Navratil, Abigail R. Dowling, Jessica L. Brown, Margaret S. Bynoe, Jianjun Xie, Kurt Scavelli, Krystal Allen-Worthington, Iain J. Clarke, Alexa M. Edmunson, Hojean Yoon
Publikováno v:
Molecular Endocrinology. 30:996-1011
Fertility in mammals requires appropriate communication within the hypothalamic-pituitary-gonadal axis and the GnRH receptor (GnRHR) is a central conduit for this communication. The GnRHR resides in discrete membrane rafts and raft occupancy is requi
Autor:
Annayya R. Aroor, Jordan J. Bartlett, Amine Belaid, Delphine Benarroch-Popivker, Patrick Brest, Michael A. Brown, Donny M. Camera, Feng Cao, Asli F. Ceylan, Abderrahman Chargui, Jing-Hai Chen, Guillemette Crépeaux, Taixing Cui, Dao-Fu Dai, Marie Angela Domdom, Harilaos Filippakis, Romain K. Gherardi, Thomas G. Gillette, Eric Gilson, Jordi Gracia-Sancho, Iris Grosjean, Sergi Guixé-Muntet, Ying Han, Ting He, Paul Hofman, Xin-Yang Hu, Guanghong Jia, Dominique Lagadic-Gossmann, Linsen Li, Jianjun Lv, Xi Ma, Sai Ma, Jipeng Ma, Kenneth Maiese, Alina Maloyan, Mickael Meyer, Chao-Yu Miao, Shigeki Miyamoto, Baharia Mograbi, Amy M. Navratil, Ida Perrotta, Thomas Pulinilkunnil, Peter S. Rabinovitch, Jun Ren, Brian Rodrigues, Barnabé Roméo, Michael N. Sack, William J. Smiles, James R. Sowers, Dondong Sun, Yong Sun, Valerie P. Tan, Yao-Liang Tang, Purvi C. Trivedi, Xuejun Wang, Chen Wang, Jian’an Wang, Pei Wang, Shuyi Wang, Lu Wang, Xu-Dong Wang, Zhao V. Wang, Chang-Chen Xiao, Zhi Yang, Mingjie Yang, Lifang Yang, Jian Yang, Nathalie Yazbeck, Hong Yu, Yingmei Zhang, Qing Zhong, Wei Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::245eff60b94ff375af887002ed9329bc
https://doi.org/10.1016/b978-0-12-805253-2.09988-0
https://doi.org/10.1016/b978-0-12-805253-2.09988-0
In humans, one highly prevalent reproductive disorder is polycystic ovary syndrome (PCOS); it is a condition characterized by anovulation, polycystic ovaries, high androgen levels, hyperinsulinemia, and predisposition for type 2 diabetes. PCOS is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d91190ae797800f2301d8cf45b408f9
https://doi.org/10.1016/b978-0-12-805253-2.00013-4
https://doi.org/10.1016/b978-0-12-805253-2.00013-4
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Frontiers in Endocrinology
Frontiers in Endocrinology
Gonadotrope cells of the anterior pituitary are characterized by their ability to mount a cyclical pattern of gonadotropin secretion to regulate gonadal function and fertility. Recent in vitro and in vivo evidence suggests that gonadotropes exhibit d