Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Amy M Inkster"'
Autor:
William Casazza, Amy M. Inkster, Giulia F. Del Gobbo, Victor Yuan, Fabien Delahaye, Carmen Marsit, Yongjin P. Park, Wendy P. Robinson, Sara Mostafavi, Jessica K. Dennis
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109047- (2024)
Summary: Molecular quantitative trait loci (QTLs) allow us to understand the biology captured in genome-wide association studies (GWASs). The placenta regulates fetal development and shows sex differences in DNA methylation. We therefore hypothesized
Externí odkaz:
https://doaj.org/article/220ea8500dd1436fa1eeef520eddff9d
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background Many human disease phenotypes manifest differently by sex, making the development of methods for incorporating X and Y-chromosome data into analyses vital. Unfortunately, X and Y chromosome data are frequently excluded from large-
Externí odkaz:
https://doaj.org/article/1576cd4ca9ce496ca3e1071d2abdd98a
Autor:
Amy M. Inkster, Chaini Konwar, Maria S. Peñaherrera, Ursula Brain, Almas Khan, E. Magda Price, Johanna M. Schuetz, Élodie Portales-Casamar, Amber Burt, Carmen J. Marsit, Cathy Vaillancourt, Tim F. Oberlander, Wendy P. Robinson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Selective serotonin reuptake inhibitors (SSRIs) for treatment of prenatal maternal depression have been associated with neonatal neurobehavioral disturbances, though the molecular mechanisms remain poorly understood. In utero exposure to SSR
Externí odkaz:
https://doaj.org/article/4841774c776f47a5b193a94364b92dc0
Autor:
Chaini Konwar, Rebecca Asiimwe, Amy M. Inkster, Sarah M. Merrill, Gian L. Negri, Maria J. Aristizabal, Christopher F. Rider, Julie L. MacIsaac, Christopher Carlsten, Michael S. Kobor
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Background Understanding the molecular basis of susceptibility factors to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It is well-established that males are more likely to acquire
Externí odkaz:
https://doaj.org/article/eb8dddcdb6ed41d08f9b4f0c914873af
Autor:
Amy M. Inkster, Victor Yuan, Chaini Konwar, Allison M. Matthews, Carolyn J. Brown, Wendy P. Robinson
Publikováno v:
Biology of Sex Differences, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Background Human placental DNA methylation (DNAme) data is a valuable resource for studying sex differences during gestation, as DNAme profiles after delivery reflect the cumulative effects of gene expression patterns and exposures across ge
Externí odkaz:
https://doaj.org/article/25c373f01d994ea4bcce1f80dc0cfee0
Autor:
Yuyin Yi, Hua Zhu, Christian Klausen, Hsun-Ming Chang, Amy M. Inkster, Jefferson Terry, Peter C. K. Leung
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Many pregnancy disorders, including early-onset preeclampsia (EOPE), are associated with defects in placental trophoblast cell invasion and differentiation during early placental development. Bone morphogenetic protein 2 (BMP2) belongs to the TGF-β
Externí odkaz:
https://doaj.org/article/0617d09752c248fb95f50d1119cf54e0
Background A growing body of literature has reported molecular and histological changes in the human placenta in association with preeclampsia (PE). Placental DNA methylation (DNAme) and transcriptomic patterns have revealed molecular subgroups of PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d37a365ef67a7d0dd4d0119d1dae30f
https://doi.org/10.21203/rs.3.rs-2949161/v1
https://doi.org/10.21203/rs.3.rs-2949161/v1
Autor:
Christopher Carlsten, Maria J. Aristizabal, Michael S. Kobor, Christopher F. Rider, Sarah M. Merrill, Amy M. Inkster, Chaini Konwar, J.L. MacIsaac, Gian Luca Negri, Rebecca Asiimwe
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-18 (2021)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background Understanding the molecular basis of susceptibility factors to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It is well-established that males are more likely to acquire SARS-CoV-
Autor:
William Casazza, Amy M. Inkster, Giulia F. Del Gobbo, Victor Yuan, Fabien Delahaye, Carmen Marsit, Yongjin P. Park, Wendy P. Robinson, Sara Mostafavi, Jessica K Dennis
SummaryMolecular quantitative trait loci (QTL) allow us to understand the biology captured in genome-wide association studies (GWAS). The placenta regulates fetal development, and shows sex differences in DNA methylation. We therefore hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::790b02a466b211fff31af3e9b2a978c5
https://doi.org/10.1101/2022.10.04.22280695
https://doi.org/10.1101/2022.10.04.22280695
Publikováno v:
Epigeneticschromatin. 16(1)
Many human disease phenotypes manifest differently by sex, making the development of methods for incorporating X and Y-chromosome data into analyses vital. Unfortunately, X and Y chromosome data are frequently excluded from large-scale analyses of th