Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Amy L. Upton"'
Autor:
Sophie Nolivos, Amy L. Upton, Anjana Badrinarayanan, Julius Müller, Katarzyna Zawadzka, Jakub Wiktor, Amber Gill, Lidia Arciszewska, Emilien Nicolas, David Sherratt
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
MukBEF, the bacterial structural maintenance of chromosomes complex, is known to associate with origins of replication and topoisomerase IV. Here the authors show an association of MukBEF with MatP and replication termination regions, important for p
Externí odkaz:
https://doaj.org/article/6b716d9d024e400391d3e0c707f7608d
Autor:
Juachi U. Dimude, Anna Stockum, Sarah L. Midgley-Smith, Amy L. Upton, Helen A. Foster, Arshad Khan, Nigel J. Saunders, Renata Retkute, Christian J. Rudolph
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT Chromosome replication is regulated in all organisms at the assembly stage of the replication machinery at specific origins. In Escherichia coli, the DnaA initiator protein regulates the assembly of replication forks at oriC. This regulation
Externí odkaz:
https://doaj.org/article/79b4d77668a248bfa16f07df16ae890e
Autor:
Emilien Nicolas, Amy L. Upton, Stephan Uphoff, Olivia Henry, Anjana Badrinarayanan, David Sherratt
Publikováno v:
mBio, Vol 5, Iss 1 (2014)
ABSTRACT The Escherichia coli structural maintenance of chromosome (SMC) complex, MukBEF, and topoisomerase IV (TopoIV) interact in vitro through a direct contact between the MukB dimerization hinge and the C-terminal domain of ParC, the catalytic su
Externí odkaz:
https://doaj.org/article/108c324e4f974d9c96c399b1d02fe71c
Autor:
Toni Taylor, Amy L. Upton, Robert G. Lloyd, Christian J. Rudolph, Juachi U. Dimude, Sarah L Midgley-Smith, Nicole M Forrester
Publikováno v:
Nucleic Acids Research
Chromosome duplication initiates via the assembly of replication forks at defined origins. Forks proceed in opposite directions until they fuse with a converging fork. Recent work highlights that fork fusions are highly choreographed both in pro- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e503b473647e0ec9d6675500447b017
http://bura.brunel.ac.uk/handle/2438/16361
http://bura.brunel.ac.uk/handle/2438/16361
Autor:
David S. Milner, Akeel A. Mahdi, Geoffrey S. Briggs, Amy L. Upton, Jane I. Grove, Robert G. Lloyd, Christian J. Rudolph
Publikováno v:
Nucleic Acids Research
RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands. Its ability to remodel replication forks and to genetically interact wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1868e3833a9bd1b9c9148d5034e7ae7
http://europepmc.org/articles/PMC4027168
http://europepmc.org/articles/PMC4027168
Publikováno v:
Nature
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Macmillan Publishers Limited. Chromosome duplication normally initiates through the assembly of replication fork complexes at def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5a4415034f48ef3e1d21ae839be4c3
https://doi.org/10.1038/nature12312
https://doi.org/10.1038/nature12312
Autor:
Amy L. Upton, David J. Sherratt
Publikováno v:
Nature Structural & Molecular Biology. 20:246-249
SMC (structural maintenance of chromosomes) protein complexes act in chromosome processing in all domains of life. In this issue, a study of the prokaryotic SMC complex Smc–ScpAB reveals an unanticipated asymmetry despite Smc forming a symmetric ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069eebb1852c3dabff7ef15483f55449
https://doi.org/10.1038/nsmb.2525
https://doi.org/10.1038/nsmb.2525
Publikováno v:
DNA Repair. 9:210-223
The RecG protein of Escherichia coli is a double-stranded DNA translocase that unwinds a variety of branched DNAs in vitro, including Holliday junctions, replication forks, D-loops and R-loops. Coupled with the reported pleiotropy of recG mutations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07313d7da2fb35a4761dda16ef071d5e
https://doi.org/10.1016/j.dnarep.2009.12.014
https://doi.org/10.1016/j.dnarep.2009.12.014
Publikováno v:
Molecular Microbiology
This is an open access article, shared under a Creative Commons licence. Copyright © 2009 The Authors. Little is known about what happens when forks meet to complete DNA replication in any organism. In this study we present data suggesting that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f1ab80c1b9d42987f96fc8608ef3c9
https://doi.org/10.1111/j.1365-2958.2009.06773.x
https://doi.org/10.1111/j.1365-2958.2009.06773.x
Publikováno v:
DNA Repair. 7:1589-1602
In dividing cells, the stalling of replication fork complexes by impediments to DNA unwinding or by template imperfections that block synthesis by the polymerase subunits is a serious threat to genomic integrity and cell viability. What happens to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fe2587ddea70f0318ebe9c5355d872
https://doi.org/10.1016/j.dnarep.2008.06.012
https://doi.org/10.1016/j.dnarep.2008.06.012