Výsledky vyhledávání - "Amy L. Stark"

Akademický článek

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

Autor: Michael T. Eadon, Ronald J. Hause, Amy L. Stark, Ying-Hua Cheng, Heather E. Wheeler, Kimberly S. Burgess, Eric A. Benson, Patrick N. Cunningham, Robert L. Bacallao, Pierre C. Dagher, Todd C. Skaar, M. Eileen Dolan

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 3, p 661 (2017)

Colistin sulfate (polymixin E) is an antibiotic prescribed with increasing frequency for severe Gram-negative bacterial infections. As nephrotoxicity is a common side effect, the discovery of pharmacogenomic markers associated with toxicity would ben

Externí odkaz: https://doaj.org/article/93de7be37c7a4ae99b01758f9019e3b6

Zobrazit plný text záznamu

Akademický článek

EPS8 inhibition increases cisplatin sensitivity in lung cancer cells.

Autor: Lidija K Gorsic, Amy L Stark, Heather E Wheeler, Shan S Wong, Hae K Im, M Eileen Dolan

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82220 (2013)

Cisplatin, a commonly used chemotherapeutic, is associated with ototoxicity, renal toxicity and neurotoxicity, thus identifying means to increase the therapeutic index of cisplatin may allow for improved outcomes. A SNP (rs4343077) within EPS8, disco

Externí odkaz: https://doaj.org/article/1f9bbadbb5ef4122a12673d49cc2f486

Zobrazit plný text záznamu

Rates of Burnout, Depression, Suicide, and Substance Use Disorders

Autor: Amy L. Stark, Katherine M. Moore, Elaine L. Stageberg

Publikováno v: Burnout in Women Physicians ISBN: 9783030444587

Knowing the epidemiological data regarding rates of burnout, depression, suicide, and substance use disorders in physicians – and specifically in women physicians – is a crucial first step in understanding and confronting this very important issu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aab36f4cfc5dd23b73468e36fd57b57
https://doi.org/10.1007/978-3-030-44459-4_3

Zobrazit plný text záznamu

Akademický článek

Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.

Autor: Hae Kyung Im, Eric R Gamazon, Amy L Stark, R Stephanie Huang, Nancy J Cox, M Eileen Dolan

Publikováno v: PLoS Genetics, Vol 8, Iss 2, p e1002525 (2012)

The International HapMap project has made publicly available extensive genotypic data on a number of lymphoblastoid cell lines (LCLs). Building on this resource, many research groups have generated a large amount of phenotypic data on these cell line

Externí odkaz: https://doaj.org/article/171a297623124dcdb540e3e8c08efc7e

Zobrazit plný text záznamu

Use of a Gabapentin Protocol for the Management of Alcohol Withdrawal: A Preliminary Experience Expanding From the Consultation-Liaison Psychiatry Service

Autor: Bruno A. Perossa, Nicholas D. Allen, Daniel K. Hosker, Daniela B. Rakocevic, Hannah K. Betcher, Ross A. Dierkhising, Jonathan G. Leung, Kristin L. Borreggine, Blaine A. Minton, Benjamin R. Braus, Elliot M. Handler, Amy L. Stark, Kemuel L. Philbrick

Publikováno v: Psychosomatics. 59:496-505

Background Benzodiazepines are the conventional mainstay to manage alcohol withdrawal; however, patients are subsequently at increased risk for poor sleep, cravings, and return to drinking. Research on alternative pharmacologic agents to facilitate s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a309558ca40aedef1f12437fcc0003e2
https://doi.org/10.1016/j.psym.2018.03.002

Zobrazit plný text záznamu

Cannabis abuse and dependence in kidney transplant candidates

Autor: Nuria J. Thusius, Daniel K. Hall-Flavin, Amy L. Stark, Terry D. Schneekloth, La Tonya J. Hickson, Victor M. Karpyak, Beth R. Larrabee

Publikováno v: J Psychosom Res

Objective Cannabis is the most commonly used non-alcohol intoxicant in the general population. There are no consistent guidelines on the implications of cannabis abuse and dependence (CAD) in kidney transplant candidates. The aims of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6bc15c84714a8675901868d39989d3
https://europepmc.org/articles/PMC6545133/

Zobrazit plný text záznamu

Identification of Novel Protein Expression Changes Following Cisplatin Treatment and Application to Combination Therapy

Autor: Ronald J. Hause, Amy L. Stark, Lidija K. Gorsic, Mark F. Ciaccio, Ashraf G. Madian, Vincent C. Chen, Amy L. Gill, Lida Anita To, M. Eileen Dolan, Sawyer W. Williams, Richard B. Jones, Claudia Wing, Kevin P. White, Jamie Myers

Publikováno v: Journal of proteome research. 16(11)

Determining the effect of chemotherapeutic treatment on changes in protein expression can provide important targets for overcoming resistance. Due to challenges in simultaneously measuring large numbers of proteins, a paucity of data exists on global

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f9342a0cf3aa09b5085c433793faf8
https://pubmed.ncbi.nlm.nih.gov/28902521

Zobrazit plný text záznamu

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

Autor: Ronald J. Hause, Pierre C. Dagher, Eric A. Benson, Kimberly S. Burgess, Robert L. Bacallao, Amy L. Stark, Heather E. Wheeler, Todd C. Skaar, Ying Hua Cheng, Michael T. Eadon, Patrick N. Cunningham, M. Eileen Dolan

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 3; Pages: 661
International Journal of Molecular Sciences, Vol 18, Iss 3, p 661 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e2d8bdcff7fc274a5a46ffd2abd1bd
http://europepmc.org/articles/PMC5372673

Zobrazit plný text záznamu

Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels

Autor: Nirav N. Antao, Sophie H. Chung, Lidija K. Gorsic, Kevin P. White, M. Eileen Dolan, Christopher D. Brown, Amy L. Stark, Lida Anita To, Daniel F. Gill, Ronald J. Hause, Shan S. Wong, Jamie Myers, Richard B. Jones

Publikováno v: The American Journal of Human Genetics. 95(2):194-208

Many genetic variants associated with human disease have been found to be associated with alterations in mRNA expression. Although it is commonly assumed that mRNA expression changes will lead to consequent changes in protein levels, methodological c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5581be26eade9521ca1c5ee02441fc

Zobrazit plný text záznamu

The Role of Gene Body Cytosine Modifications in MGMT Expression and Sensitivity to Temozolomide

Autor: Lucy A. Godley, M. Eileen Dolan, Amy L. Stark, Erika L. Moen, Wei Zhang

Publikováno v: Molecular Cancer Therapeutics. 13:1334-1344

The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) is known to play a role in sensitivity to temozolomide. Promoter hypermethylation of MGMT is commonly used to predict low expression levels of MGMT in gliomas, despite observed disc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9450f5ca5d9e1ab43c7a3515e65ea814
https://doi.org/10.1158/1535-7163.mct-13-0924

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání