Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Amy L. Milton"'
Autor:
Amy L. Milton
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Since its rediscovery at the beginning of the 21st Century, memory reconsolidation has been proposed to be a therapeutic target for reducing the impact of emotional memories that can go awry in mental health disorders such as drug addiction
Externí odkaz:
https://doaj.org/article/7f39c41493df40e895239079cf4f8b06
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2024)
Externí odkaz:
https://doaj.org/article/d2db47ef1689430e943bb9c7041f5c19
Autor:
Ethan G. Dutcher, Laura Lopez-Cruz, E. A. Claudia Pama, Mary-Ellen Lynall, Iris C. R. Bevers, Jolyon A. Jones, Shahid Khan, Stephen J. Sawiak, Amy L. Milton, Menna R. Clatworthy, Trevor W. Robbins, Edward T. Bullmore, Jeffrey W. Dalley
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Early-life stress (ELS) or adversity, particularly in the form of childhood neglect and abuse, is associated with poor mental and physical health outcomes in adulthood. However, whether these relationships are mediated by the consequences of
Externí odkaz:
https://doaj.org/article/fd561f9d616d4904bddd36a9d6dd5cec
Autor:
Katharina Zühlsdorff, Laura López-Cruz, Ethan G. Dutcher, Jolyon A. Jones, Claudia Pama, Stephen Sawiak, Shahid Khan, Amy L. Milton, Trevor W. Robbins, Edward T. Bullmore, Jeffrey W. Dalley
Publikováno v:
Neurobiology of Stress, Vol 22, Iss , Pp 100507- (2023)
Major depressive disorder (MDD) is a stress-related condition hypothesized to involve aberrant reinforcement learning (RL) with positive and negative stimuli. The present study investigated whether repeated early maternal separation (REMS) stress, a
Externí odkaz:
https://doaj.org/article/5a22d5be03f24cbcabfa849082431ca6
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Maladaptive emotional memories contribute to the persistence of many mental health disorders, and therefore the prospect of disrupting these memories to produce long-term reductions in relapse is of great clinical appeal. Reducing the impact of malad
Externí odkaz:
https://doaj.org/article/25a7d03ac1424910bdad108eee44f1f3
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
Addicted individuals are highly susceptible to relapse when exposed to drug-associated conditioned stimuli (CSs; “drug cues”) even after extensive periods of abstinence. Until recently, these maladaptive emotional drug memories were believed to b
Externí odkaz:
https://doaj.org/article/d22015609bb9427b80e72d196438c163
Autor:
Amy L. Milton
Publikováno v:
F1000Research, Vol 8 (2019)
Fear is a highly adaptive emotion that has evolved to promote survival and reproductive fitness. However, maladaptive expression of fear can lead to debilitating stressor-related and anxiety disorders such as post-traumatic stress disorder. Although
Externí odkaz:
https://doaj.org/article/02e703b51e574d958c8e827c5e4b5f94
Autor:
Uyen T.D. Bui, Amy L Milton
Reconsolidation results in the restabilisation, and thus persistence, of a memory made labile by retrieval, and interfering with this process is thought to enable modification or weakening of the original trace. As such, reconsolidation-blockade has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd30cf011d6987b931812e3b1792a1a
https://www.repository.cam.ac.uk/handle/1810/348584
https://www.repository.cam.ac.uk/handle/1810/348584
Autor:
Amy L. Milton, Josh Ferencik, John Chen, Federico Rotondo, Kathryn Biddle, Mathilde d'Esneval
Publikováno v:
Neuroscience. 480:9-18
The prospect of exploiting memory reconsolidation to treat mental health disorders has received great research interest, particularly following demonstrations that the β-adrenergic receptor antagonist propranolol, which is safe for use in humans, ca
Autor:
Katharina Zühlsdorff, Laura López-Cruz, Ethan G. Dutcher, Jolyon A. Jones, Claudia Pama, Stephen Sawiak, Shahid Khan, Amy L. Milton, Trevor W. Robbins, Edward T. Bullmore, Jeffrey W. Dalley
Publikováno v:
Neurobiology of stress. 22
Major depressive disorder (MDD) is a stress-related condition hypothesized to involve aberrant reinforcement learning (RL) with positive and negative stimuli. The present study investigated whether repeated early maternal separation (REMS) stress, a