Výsledky vyhledávání - "Amy L. Dugan"

Mice Treated With a Benzodiazepine Had an Improved Survival Rate Following Pseudomonas aeruginosa Infection

Autor: George F. Babcock, Alice N. Neely, Karen A. Gregerson, Amy L. Dugan, Nelson D. Horseman, Greg Noel, Jason D. Gardner

Publikováno v: Journal of Burn Care & Research. 31:1-12

Psychological stress has a high incidence after burn injury, therefore, anxiolytic drugs are often prescribed. Unfortunately, to date, no burn study has investigated the effects of anxiolytic drugs on the ability to fight infection. This study was un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb3c506ab5ac3e873d454357e66ec8e
https://doi.org/10.1097/bcr.0b013e3181cb8e82

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Stress and Prolactin Effects on Bone Marrow Myeloid Cells, Serum Chemokine and Serum Glucocorticoid Levels in Mice

Autor: Karen A. Gregerson, Donna J. Buckley, Greg Noel, Cora K. Ogle, Amy L. Dugan, Sandy Schwemberger, George F. Babcock, Nelson D. Horseman

Publikováno v: Neuroimmunomodulation. 14:287-296

Objective: Current evidence supports the conclusion that prolactin (PRL) is not an obligate immunoregulatory hormone and influences the immune system predominantly during stress conditions. In this study, we examined the impact of PRL on the psychoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7cac6d10fb92424ac6f9d6c86debd67
https://doi.org/10.1159/000117810

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Serum Levels of Prolactin, Growth Hormone, and Cortisol in Burn Patients: Correlations with Severity of Burn, Serum Cytokine Levels, and Fatality

Autor: Cora K. Ogle, W. B. Malarkey, Amy L. Dugan, Edward C. Jauch, Sandy Schwemberger, Nelson D. Horseman

Publikováno v: The Journal of Burn Care & Rehabilitation. 25:306-313

In this study, we measured serum prolactin (PRL), cortisol, growth hormone, interleukin (IL)-1β, IL-6, IL-8, IL-10, IL-12, and tumor necrosis factor-α in patients admitted with small-to-moderate burn injuries. Serum samples were obtained at the tim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c888bdf98f92182f950f6a36f1476107
https://doi.org/10.1097/01.bcr.0000124785.32516.cb

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Effects of Prolactin Deficiency on Myelopoiesis and Splenic T Lymphocyte Proliferation in Thermally Injured Mice

Autor: Olivier Thellin, Donna J. Buckley, Nelson D. Horseman, Amy L. Dugan, Cora K. Ogle, Arthur R. Buckley

Publikováno v: Endocrinology. 143:4147-4151

The importance of prolactin (PRL) in mammopoiesis and milk production is undisputed. However, previous studies investigating the role of PRL in immune function have yielded inconsistencies. These inconsistencies have led to our hypothesis that the im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a8c09ff67e12fd9934afbb37bd9e62
https://doi.org/10.1210/en.2002-220515

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Direct Inhibition of in Vitro PLD Activity by 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride

Autor: Brooke J. Andrews, Jason A. Lehman, Kristina Bond, Julia Gomez-Cambronero, Jeffrey M. Horn, Amy L. Dugan

Publikováno v: Biochemical and Biophysical Research Communications. 273:302-311

While conducting a purification protocol of phospholipase D (PLD) from human granulocytes, we observed that PLD activity was inhibited by a commonly-used protease inhibitor cocktail. Of the six inhibitors present in the cocktail, the serine protease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e367fa7a37500ad973ace456f1fe03d
https://doi.org/10.1006/bbrc.2000.2938

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The burn wound inflammatory response is influenced by midazolam

Autor: Laura L. Hernandez, Amy L. Dugan, George F. Babcock, Sandy Schwemberger, Ekta Yadav

Publikováno v: Inflammation. 35(1)

Burn patients requiring hospitalization are often treated for anxiety with benzodiazepines (BDZs). Benzodiazepines are reported to influence immune system function. Immune system alterations are a major cause of burn-induced mortality. We wanted to d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557bdd5c578046f0792a237583993b6f
https://pubmed.ncbi.nlm.nih.gov/21400122

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Psychogenic stress prior to burn injury has differential effects on bone marrow and cytokine responses

Autor: Amy L, Dugan, Sandy, Schwemberger, Greg J, Noel, George, Babcock, Cora K, Ogle, Nelson D, Horseman

Publikováno v: Experimental biology and medicine (Maywood, N.J.). 232(2)

It is well known that many burn patients experience psychopathological disorders prior to burn injury. However, it is not known whether individuals that have been exposed to chronic psychological stresses will respond differently than unstressed indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cb3c95809e7432d75bdd6b161f3f10bb
https://pubmed.ncbi.nlm.nih.gov/17259333

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Effects of prolactin level on burn-induced aberrations in myelopoiesis

Autor: Donna J. Buckley, Sandy Schwemberger, Nelson D. Horseman, Amy L. Dugan, Cora K. Ogle, George F. Babcock, Arthur R. Buckley

Publikováno v: Shock (Augusta, Ga.). 21(2)

In this study, we sought to determine if prolactin (PRL) had any influence on burn-induced alterations in myelopoiesis and serum IL-6, IL-10, IL-12, IFN-gamma, TNF-alpha, and MCP-1 levels. To do this, we used mice that were PRL normal, PRL deficient,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6544991f9a94ef5436b60a6f51a9b77
https://pubmed.ncbi.nlm.nih.gov/14752289

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