Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.

Autor: Amy L Stark, Ronald J Hause, Lidija K Gorsic, Nirav N Antao, Shan S Wong, Sophie H Chung, Daniel F Gill, Hae K Im, Jamie L Myers, Kevin P White, Richard Baker Jones, M Eileen Dolan

Publikováno v: PLoS Genetics, Vol 10, Iss 4, p e1004192 (2014)

Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as expression quantitative trait loci is an expanding and useful approach, but focuses exclusively on mRNA r

Externí odkaz: https://doaj.org/article/d70e8f5d77ad47efb599e099fdb8de61

Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.

Autor: Hae Kyung Im, Eric R Gamazon, Amy L Stark, R Stephanie Huang, Nancy J Cox, M Eileen Dolan

Publikováno v: PLoS Genetics, Vol 8, Iss 2, p e1002525 (2012)

The International HapMap project has made publicly available extensive genotypic data on a number of lymphoblastoid cell lines (LCLs). Building on this resource, many research groups have generated a large amount of phenotypic data on these cell line

Externí odkaz: https://doaj.org/article/171a297623124dcdb540e3e8c08efc7e

Rates of Burnout, Depression, Suicide, and Substance Use Disorders

Autor: Amy L. Stark, Katherine M. Moore, Elaine L. Stageberg

Publikováno v: Burnout in Women Physicians ISBN: 9783030444587

Knowing the epidemiological data regarding rates of burnout, depression, suicide, and substance use disorders in physicians – and specifically in women physicians – is a crucial first step in understanding and confronting this very important issu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aab36f4cfc5dd23b73468e36fd57b57
https://doi.org/10.1007/978-3-030-44459-4_3

Cannabis abuse and dependence in kidney transplant candidates

Autor: Nuria J. Thusius, Daniel K. Hall-Flavin, Amy L. Stark, Terry D. Schneekloth, La Tonya J. Hickson, Victor M. Karpyak, Beth R. Larrabee

Publikováno v: J Psychosom Res

Objective Cannabis is the most commonly used non-alcohol intoxicant in the general population. There are no consistent guidelines on the implications of cannabis abuse and dependence (CAD) in kidney transplant candidates. The aims of this study were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6bc15c84714a8675901868d39989d3
https://europepmc.org/articles/PMC6545133/

Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach

Autor: Ronald J. Hause, Pierre C. Dagher, Eric A. Benson, Kimberly S. Burgess, Robert L. Bacallao, Amy L. Stark, Heather E. Wheeler, Todd C. Skaar, Ying Hua Cheng, Michael T. Eadon, Patrick N. Cunningham, M. Eileen Dolan

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 3; Pages: 661
International Journal of Molecular Sciences, Vol 18, Iss 3, p 661 (2017)

Colistin sulfate (polymixin E) is an antibiotic prescribed with increasing frequency for severe Gram-negative bacterial infections. As nephrotoxicity is a common side effect, the discovery of pharmacogenomic markers associated with toxicity would ben

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e2d8bdcff7fc274a5a46ffd2abd1bd
http://europepmc.org/articles/PMC5372673